Results 41 to 50 of about 36,930 (233)

Criteria for the diagnosis of corticobasal degeneration [PDF]

, 2013
Current criteria for the clinical diagnosis of pathologically confirmed corticobasal degeneration (CBD) no longer reflect the expanding understanding of this disease and its clinicopathologic correlations.
Armstrong, Melissa J, Bak, Thomas H, Bhatia, Kailash P, Borroni, Barbara, Boxer, Adam L, Dickson, Dennis W, Grossman, Murray, Hallett, Mark, Josephs, Keith A, Kertesz, Andrew, Lang, Anthony E, Lee, Suzee E, Litvan, Irene, Miller, Bruce L, Reich, Stephen G, Riley, David E, Tolosa, Eduardo, Tröster, Alexander I, Vidailhet, Marie, Weiner, William J   +19 more
core   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Spelling Intervention in Post-Stroke Aphasia and Primary Progressive Aphasia

Behavioural Neurology, 2013
Spelling–a core language skill–is commonly affected in neurological diseases such as stroke and Primary Progressive Aphasia (PPA). We present two case studies of the same spelling therapy (learning of phoneme-to-grapheme correspondences with help from ...
Kyrana Tsapkini, Argye E. Hillis
doaj   +1 more source

A presumptive association between obsessive compulsions and asymmetric temporal lobe atrophy: a case report

Journal of Medical Case Reports, 2022
Background The relatively isolated atrophy of the temporal lobes leads to a clinical radiological pattern, referred to as the temporal variant of frontotemporal dementia.
Thiago Paranhos, Tiago Lucas, Antonio de Salles, Jorge Moll, Ricardo de Oliveira-Souza   +4 more
doaj   +1 more source

Eligibility for Anti‐Amyloid‐β Monoclonal Antibodies in Patients With Primary Progressive Aphasia due to Alzheimer's Disease in Japan [PDF]

Psychogeriatrics
ABSTRACT Background Primary progressive aphasia (PPA) is a clinical syndrome characterized by progressive language impairment. The logopenic variant (lvPPA) is frequently associated with Alzheimer's disease (AD) pathology. With the approval of anti‐amyloid‐β monoclonal antibodies, such as lecanemab and donanemab, for the treatment of AD, accurately ...
Inagawa S, Inagawa Y, Tsugawa A, Takenoshita N, Saito K, Ishii K, Kasuga K, Ikeuchi T, Shimizu S.   +8 more
europepmc   +2 more sources

Progressive Apraxia of Speech: Might There Be Subtypes? [PDF]

, 2013
This study examined speech and language characteristics of three groups of individuals with neurodegenerative disease: (1) primary progressive apraxia of speech (AOS) without aphasia (N=18), (2) agrammatic primary progressive aphasia (agPPA) less severe ...
Duffy, Joseph R., Josephs, Keith A., Strand, Edythe E., Whitwell, Jennifer L.   +3 more
core  

Divergent longitudinal propagation of white matter degradation in logopenic and semantic variants of primary progressive aphasia [PDF]

, 2015
Background: Clinico-pathological distinction of primary progressive aphasia (PPA) can be challenging at clinic presentation. In particular, cross-sectional neuroimaging signatures across the logopenic (lvPPA) and semantic (svPPA) variants are difficult ...
Agosta, Bach, Brambati, Chare, Deramecourt, Fletcher, Galantucci, Gorno-Tempini, Gorno-Tempini, Heim, Hickok, Keihaninejad, Lam, Mackenzie, Mahoney, Mesulam, Mesulam, Mioshi, Mioshi, Nichols, Powers, Rohrer, Rohrer, Saur, Savage, Smith, Smith, Smith, Varentsova, Wicklund, Zhang   +30 more
core   +1 more source

Postictal self‐removal of intracerebral electrodes during stereoelectroencephalography monitoring: A case series

Epileptic Disorders, EarlyView.
Abstract Epilepsy surgery remains the most effective treatment for focal drug‐resistant epilepsy, and stereoelectroencephalography (SEEG) is increasingly used to define the epileptogenic‐zone network (EZN) and guide curative or palliative interventions.
Ionuț‐Flavius Bratu, Romain Carron, Julia Makhalova, Stanislas Lagarde, Fabrice Bartolomei   +4 more
wiley   +1 more source

Primary progressive aphasia.

Cleveland Clinic Journal of Medicine, 2007
The diagnosis of primary progressive aphasia (PPA) is made in any patient in whom a language impairment (aphasia), caused by a neurodegenerative disease (progressive), constitutes the most salient aspect of the clinical picture (primary). The language impairment can be fluent or nonfluent and may or may not interfere with word comprehension. Memory for
openaire   +4 more sources

Comprehension of wh-questions in a case of mixed dementia [PDF]

, 2011
We investigated processing of wh-questions and declarative sentences with differing syntactic complexity in a case of mixed dementia (FA). FA was impaired in her ability to understand syntactically complex declarative sentences and syntactically complex
Saddy, J. Doug, Salis, Chris
core   +4 more sources