Results 41 to 50 of about 381,033 (292)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

The BSD Socket API for Simulator [PDF]

open access: yes, 2007
BSD Socket API for Simulator is a project to run untouched Real World Application (RWA) binaries on the powerful modern general-purpose network simulators.
Liu, Zhiwei
core  

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

A security analysis of authentication and authorization implemented in web applications based on the REST architecture

open access: yesJournal of Computer Sciences Institute, 2020
The purpose of this article is to prepare a security analysis of authentication and authorization mechanisms in web applications based on the REST architecture. The article analyzes the problems encountered during the implementation of the JSON Web Token
Tomasz Muszyński, Grzegorz Koziel
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Métricas de APIs: Catálogo y Herramienta OMA

open access: yesInformes Científicos y Técnicos (Universidad Nacional de la Patagonia Austral), 2023
En la actualidad, las APIs web tienen un gran valor para el desarrollo de aplicaciones, ya sean web, cloud, móvil, u otras. Cumplen un papel de suma importancia, y son utilizadas ampliamente por grandes empresas alrededor del mundo, tales como Google o ...
Uriel Paredes   +2 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

APIE DENOTACIJĄ

open access: yesProblemos, 2012
Bertrando Russello "On Denoting" vertimas į lietuvių kalbą. Vertė Jonas Dagys. 
openaire   +4 more sources

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Malware detection based on visualization of recombined API instruction sequence

open access: yesConnection Science, 2022
This paper introduces a malware detection method based on the reorganisation of API instruction sequence and image representation in an effort to address the challenges posed by current methods of malware detection in terms of feature extraction and ...
Hongyu Yang   +3 more
doaj   +1 more source

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