Results 41 to 50 of about 381,033 (292)
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
The BSD Socket API for Simulator [PDF]
BSD Socket API for Simulator is a project to run untouched Real World Application (RWA) binaries on the powerful modern general-purpose network simulators.
Liu, Zhiwei
core
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
The purpose of this article is to prepare a security analysis of authentication and authorization mechanisms in web applications based on the REST architecture. The article analyzes the problems encountered during the implementation of the JSON Web Token
Tomasz Muszyński, Grzegorz Koziel
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Métricas de APIs: Catálogo y Herramienta OMA
En la actualidad, las APIs web tienen un gran valor para el desarrollo de aplicaciones, ya sean web, cloud, móvil, u otras. Cumplen un papel de suma importancia, y son utilizadas ampliamente por grandes empresas alrededor del mundo, tales como Google o ...
Uriel Paredes +2 more
doaj +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Bertrando Russello "On Denoting" vertimas į lietuvių kalbą. Vertė Jonas Dagys.
openaire +4 more sources
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Malware detection based on visualization of recombined API instruction sequence
This paper introduces a malware detection method based on the reorganisation of API instruction sequence and image representation in an effort to address the challenges posed by current methods of malware detection in terms of feature extraction and ...
Hongyu Yang +3 more
doaj +1 more source

