Results 41 to 50 of about 3,530,570 (320)
Endomyocardial fibrosis presenting as apical calcification and infective endocarditis [PDF]
European Heart Journal, 2019 A 46-year-old woman was admitted for suspected infective endocarditis. Echocardiography showed a mobile mass attached to the thickened endocardium of the left ventricular apex. Histological examination showed extensive endomyocardial fibrosis.
Aikawa, Tadao +3 more
openaire +3 more sources
The binding of a monoclonal antibody to the apical region of SCARB2 blocks EV71 infection
Protein & Cell, 2017 Entero virus 71 (EV71) causes hand, foot, and mouth disease (HFMD) and occasionally leads to severe neurological complications and even death. Scavenger receptor class B member 2 (SCARB2) is a functional receptor for EV71, that mediates viral attachment,
Xuyuan Zhang +9 more
semanticscholar +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Root Microbiota in Primary and Secondary Apical Periodontitis
Frontiers in Microbiology, 2018 Apical periodontitis is an inflammatory disease of the dental periradicular tissues triggered by bacteria colonizing necrotic root canals. Primary apical periodontitis results from the microbial colonization of necrotic pulp tissues.
Serge Bouillaguet +7 more
doaj +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Journal of Applied Oral Science, 2006 Evidence suggests that diabetic patients are more significantly affected by problems of endodontic origin. This study sought to radiographically and histologically examine the development of periradicular inflammation in control and in diabetic rats ...
Luci Armada-Dias +6 more
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Pyrosequencing analysis of apical microbiota of teeth with persistent apical periodontitis
Journal of Dental Sciences, 2015 Background/purpose: Bacteria inside and outside the root canal at the apical area are crucial for persistent periapical infection. Thus, we aimed to investigate the composition and diversity of apical microbiota in persistent apical periodontitis lesions.
Yifan Ping, Juan Wang, Jingping Liang
doaj +1 more source
Gut Microbes, 2021 Salmonella pathogenicity island (SPI) 2 type three secretion system (T3SS)-mediated effector molecules facilitate bacterial survival in phagocytes but their role in the intestinal epithelium in vivo remains ill-defined.
Marcus Fulde +17 more
doaj +1 more source
Surface Hydration Protects Cystic Fibrosis Airways from Infection by Restoring Junctional Networks
Cells, 2022 Defective hydration of airway surface mucosa is associated with recurrent lung infection in cystic fibrosis (CF), a disease caused by CF transmembrane conductance regulator (CFTR) gene mutations.
Juliette L. Simonin +6 more
doaj +1 more source