Results 51 to 60 of about 263,028 (274)

API-Miner: an API-to-API Specification Recommendation Engine

Proceedings of the 1st IEEE/ACM Workshop on Software Engineering Challenges in Financial Firms
When designing a new API for a large project, developers need to make smart design choices so that their code base can grow sustainably. To ensure that new API components are well designed, developers can learn from existing API components. However, the lack of standardized methods for comparing API designs makes this learning process time-consuming ...
Sae Young Moon, Gregor Kerr, Fran Silavong, Sean Moran   +3 more
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Invisibility as a structural determinant: Mortality outcomes of Asians and Pacific Islanders experiencing homelessness

Frontiers in Public Health, 2023
IntroductionAsians and Pacific Islanders (APIs) who are experiencing homelessness are situated in a social intersection that has rendered them unrecognized and therefore vulnerable.
Jamie Suki Chang, Katherine Saxton, Georgia Bright, Maya S. Ryan, E. Francis Lai, Michelle A. Jorden, Andy Gutierrez   +6 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

INFORMACIJA APIE AUTORIUS

Acta Paedagogica Vilnensia, 2013
ZITA ABRAMAVIČIŪTĖ – muzikos magistrė, Lietuvos edukologijos universiteto Sociali­nės edukacijos fakulteto socialinių mokslų (edukologijos) doktorantė, Lietuvos mu­zikos ir teatro akademijos Mokslo centro jaunesnioji mokslo darbuotoja. Mokslinių interesų sritys: muzikos terapija / muzikos terapija neuroreabilitacijoje, neįgaliųjų so­cialinė integracija.
openaire   +21 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Comprehensive and Accurate Molecular Profiling of Breast Cancer through mRNA Expression of ESR1, PGR, ERBB2, MKI67, and a Novel Proliferation Signature

Diagnostics
Background: An accurate status determination of breast cancer biomarkers (ER, PR, HER2, Ki67) is crucial for guiding patient management. The “gold standard” for assessing these biomarkers in FFPE tissue is IHC, which faces challenges in standardization ...
Anne-Sophie Wegscheider, Joanna Gorniak, Sara Rollinson, Leanne Gough, Navdeep Dhaliwal, Agustin Guardiola, Anna Gasior, Denise Helmer, Zoe Pounce, Axel Niendorf   +9 more
doaj   +1 more source

Changes in Antioxidant Enzymes Activity and Metabolomic Profiles in the Guts of Honey Bee (Apis mellifera) Larvae Infected with Ascosphaera apis

Insects, 2020
The fungus Ascosphaera apis, an obligate fungal pathogen of honey bee brood, causes chalkbrood disease in honey bee larvae worldwide. Biological characteristics of the fungal pathogen and the molecular interactions between A.
Zhiguo Li, Mengshang Hou, Yuanmei Qiu, Bian Zhao, Hongyi Nie, Songkun Su   +5 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Novel active pharmaceutical ingredients from India: The actors-Part-I

MGM Journal of Medical Sciences, 2021
Sixteen novel active pharmaceutical ingredients, namely Urea stibamine, Methaqualone, Enfenamic acid, Hamycin, Centimizole, Centbutindole, Ormiloxifene, Centpropazine, Centbucridine, Alpha-beta-arteether, Bulaquine, Chandonium Iodide, Sintamil ...
Prasanta Kumar Ghosh
doaj   +1 more source