Results 71 to 80 of about 111,354 (312)

Varroasis y mécanismos de defensa de la abeja melífera (Apis mellifera)

Revista de Producción Animal, 2019
Antecedentes: La abeja melífera se encuentra amenazada por varios factores que provocan lo que hoy en día se conoce a nivel mundial como el Síndrome de Colapso de las colmenas, entre los cuales destaca la presencia del ácaro Varroa destructor.
Diego Armando Masaquiza Moposita , Lino Miguel Curbelo , Byron Leoncio Díaz Monroy , Amílcar Arenal Cruz   +3 more
doaj  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Evaluating an RNA-based test for proliferation assessment and recurrence prediction in early HR+/HER2− breast cancer

Pathology and Oncology Research
Multigene signatures like Oncotype DX and Prosigna Prediction Analysis of Microarray 50 (PAM50) help estimate distant recurrence risk in patients with luminal breast cancer receiving endocrine therapy.
Marcus Vetter, Marcus Vetter, Elena Diana Chiru, Anna Gasior, Joanna Gorniak, Sara Rollinson, Leanne Gough, Mathew Harrison, Martina Sonderegger-Stalder, Martina Sonderegger-Stalder, Matthias Matter, Matthias Matter, Simone Muenst, Simone Muenst, Christian Kurzeder, Christian Kurzeder   +15 more
doaj   +1 more source

Apis iridescent virus and “clustering disease” of Apis cerana

Journal of Invertebrate Pathology, 1978
Abstract Apis iridescent virus was plentiful in each of several samples of adult individuals of Apis cerana from sick colonies in Kashmir and Northern India. Almost every bee, of those examined individually, was infected with the virus, which caused an easily detectable iridescence in the fat body and most other internal organs.
Bailey, L., Ball, B. V.
openaire   +2 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Personajes queer en la animación infantil: el caso de Boing

Anuario Electrónico de Estudios en Comunicación Social "Disertaciones"
El objetivo principal de este artículo es comprender cómo es la representación del colectivo LGTBQ+ en las series de animación de emisión en España. Para ello, se llevó a cabo un análisis de contenido sobre una muestra de 169 personajes, extraídos de ...
Apis Mediavilla-Lomas, Beatriz González de Garay   +1 more
doaj   +1 more source

Long-Term Temporal Trends of Nosema spp. Infection Prevalence in Northeast Germany: Continuous Spread of Nosema ceranae, an Emerging Pathogen of Honey Bees (Apis mellifera), but No General Replacement of Nosema apis

Frontiers in Cellular and Infection Microbiology, 2017
The Western honey bee (Apis mellifera) is widely used as commercial pollinator in worldwide agriculture and, therefore, plays an important role in global food security.
Sebastian Gisder, Vivian Schüler, Lennart L. Horchler, Detlef Groth, Elke Genersch, Elke Genersch   +5 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source