Results 91 to 100 of about 46,421 (267)
An API for Ontology Alignment [PDF]
, 2004 Ontologies are seen as the solution to data heterogeneity on the web. However, the available ontologies are themselves source of heterogeneity. This can be overcome by aligning ontologies, or finding the correspondence between their components. These alignments deserve to be treated as objects: they can be referenced on the web as such, be completed by
openaire +2 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
A honey bee fossil (Hymenoptera, Apidae) from the Late Pliocene to Early Pleistocene Teragi Group, Hyogo Prefecture, Japan: Bridging a gap in Apis evolutionary history [PDF]
ZooKeysA new fossil honey bee Apis (Apis) aibai sp. nov. was discovered in the Late Pliocene–Early Pleistocene lacustrine deposit in Hyogo Prefecture, Japan.
Yui Takahashi, Jun-ichi Takahashi
doaj +3 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Apis (Apis) mellifera Linnaeus 1758
, 2017 Published as part of Straka, Jakub, Batelka, Jan & Pauly, Alain, 2017, Bees of the Socotra Archipelago (Hymenoptera: Anthophila), their biogeography and association with parasites, pp. 183-219 in Acta Entomologica Musei Nationalis Pragae (Acta. Ent. Mus. Natl. Pragae) (Acta. Ent. Mus. Natl.
Straka, Jakub +2 more
openaire +2 more sources
Evolutionary trends in Bombella apis CRISPR-Cas systems
mSystemsBacteria and archaea employ a rudimentary immune system, CRISPR-Cas, to protect against foreign genetic elements such as bacteriophage. CRISPR-Cas systems are found in Bombella apis. B.
Carrie L. Ganote +4 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Apis (Apis) mellifera Linnaeus 1758
, 2008 Published as part of Genaro, Julio A. & Franz, Nico M., 2008, The bees of Greater Puerto Rico (Hymenoptera: Apoidea: Anthophila), pp.
Genaro, Julio A., Franz, Nico M.
openaire +2 more sources
Mitochondrial DNA. Part B. Resources, 2017 We sequenced almost complete mitochondrial genome of Apis florea (Insecta: Hymenoptera: Apocrita: Apidae) with length of 15,933 bp. The genome has similar codon usage and gene organization to those of mitogenome reported for other Hymenoptera.
Jie Yang, Jianxin Xu, Shaoyu He, Jie Wu
doaj +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source