Results 101 to 110 of about 111,354 (312)
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Knowledge discovery meets linked APIs
, 2013 Knowledge Discovery and Data Mining (KDD) is a very wellestablished research field with useful techniques that explore patterns and regularities in large relational, structured and unstructured datasets.
Hoxha, Julia +2 more
core +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Survival rate of honeybee (Apis mellifera) workers after exposure to sublethal concentrations of imidacloprid [PDF]
, 2010 Imidacloprid is a commonly used systemic insecticide which can induce several sublethal effects. Previous research has not shown any increased mortality in bees that were fed with sublethal doses. However, there is very little research conducted with the
Blacquiere, T.
core
Evolution of queen pheromone receptor tuning in four honeybee species (Hymenoptera, Apidae, Apis)
iScienceSummary: Honeybees (genus: Apis) use a plethora of pheromones for intraspecific communication. The primary compound produced by the queen’s mandibular glands, 9-ODA, is involved in mating in all Apis species. It is the ligand of the most highly expressed
Julia Mariette +10 more
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Pediatric blood culture: time to positivity
The Turkish Journal of Pediatrics, 2004 The aim of this study was to determine how long it takes blood culture to become positive using a blood culture system that can be monitored continuously in pediatric patients.
Ateş Kara +4 more
doaj
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
The fate of active pharmaceutical ingredients in a hydrothermal liquefaction process
Discover Applied SciencesSewage sludge contains active pharmaceutical ingredients (APIs) that persist after anaerobic digestion, posing challenges for its direct use as an organic amendment.
Stian Hersvik Hegdahl +5 more
doaj +1 more source
Genetic diversity of Apis cerana cerana based on mitochondrial DNA in Lishui, Zhejiang, China
浙江大学学报. 农业与生命科学版, 2017 Apis cerana cerana is a native honeybee species in China, which is widely distributed in all parts of the country, especially in the hills and mountains of the South China. Apis mellifera was introduced into China in the end of the 19th century.
CAO Lianfei, GU Peipei, LIN Yuqing
doaj +1 more source