Results 81 to 90 of about 263,028 (274)
City of Zagreb Spatial Data Infrastructure
Through the establishment of the Coordination Group for the City of Zagreb Spatial Management IT System, the City of Zagreb has become actively involved in the wider global community by setting up the Zagreb Spatial Data Infrastructure (ZSDI) service. In
Darko Šiško +3 more
doaj
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
A linked data-driven & service-oriented architecture for sharing educational resources [PDF]
The two fundamental aims of managing educational resources are to enable resources to be reusable and interoperable and to enable Web-scale sharing of resources across learning communities.
Dietze, Stefan +8 more
core
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Evolution of queen pheromone receptor tuning in four honeybee species (Hymenoptera, Apidae, Apis)
Summary: Honeybees (genus: Apis) use a plethora of pheromones for intraspecific communication. The primary compound produced by the queen’s mandibular glands, 9-ODA, is involved in mating in all Apis species. It is the ligand of the most highly expressed
Julia Mariette +10 more
doaj +1 more source
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Genetic diversity of Apis cerana cerana based on mitochondrial DNA in Lishui, Zhejiang, China
Apis cerana cerana is a native honeybee species in China, which is widely distributed in all parts of the country, especially in the hills and mountains of the South China. Apis mellifera was introduced into China in the end of the 19th century.
CAO Lianfei, GU Peipei, LIN Yuqing
doaj +1 more source
Asian/Pacific Islander Communities: An Agenda for Positive Action [PDF]
In June of 2001 the National Council on Crime and Delinquency, in cooperation with the John D. and Catherine T. MacArthur Foundation, convened a symposium to assess the current state of research, exchange information, and establish a tentative agenda for
core
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source

