Results 81 to 90 of about 46,421 (267)
Evolution of queen pheromone receptor tuning in four honeybee species (Hymenoptera, Apidae, Apis)
iScienceSummary: Honeybees (genus: Apis) use a plethora of pheromones for intraspecific communication. The primary compound produced by the queen’s mandibular glands, 9-ODA, is involved in mating in all Apis species. It is the ligand of the most highly expressed
Julia Mariette +10 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Genetic diversity of Apis cerana cerana based on mitochondrial DNA in Lishui, Zhejiang, China
浙江大学学报. 农业与生命科学版, 2017 Apis cerana cerana is a native honeybee species in China, which is widely distributed in all parts of the country, especially in the hills and mountains of the South China. Apis mellifera was introduced into China in the end of the 19th century.
CAO Lianfei, GU Peipei, LIN Yuqing
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Pediatric blood culture: time to positivity
The Turkish Journal of Pediatrics, 2004 The aim of this study was to determine how long it takes blood culture to become positive using a blood culture system that can be monitored continuously in pediatric patients.
Ateş Kara +4 more
doaj
Prioritisation of data-poor pharmaceuticals for empirical testing and environmental risk assessment
Environment InternationalThere are more than 3,500 active pharmaceutical ingredients (APIs) on the global market for human and veterinary use. Residues of these APIs eventually reach the aquatic environment.
Cristiana Cannata +7 more
doaj +1 more source
Mining Collaboration Patterns Between APIs for Mashup Creation in Web of Things
IEEE Access, 2019 The Web of Things (WoT) extends the concept of “Internet of Things (IoT)” in that smart devices in the physical world can be interacted with or integrated via popular web technologies (e.g., HTML, HTTP, and Web API).
Mingdong Tang +5 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source