Results 61 to 70 of about 46,421 (267)

Development of an electrochemical biosensor based on rGO/Ag₂S-Au nanocomposites and L-CHA dual signal amplification for miR-155 detection

open access: yesBiomedical Analysis
MicroRNA-155 (miR-155) is a critical biomarker implicated in various pathological processes, including cancer progression, immune response, and cardiovascular diseases.
Shan Ou   +5 more
doaj   +1 more source

Long-Term Temporal Trends of Nosema spp. Infection Prevalence in Northeast Germany: Continuous Spread of Nosema ceranae, an Emerging Pathogen of Honey Bees (Apis mellifera), but No General Replacement of Nosema apis

open access: yesFrontiers in Cellular and Infection Microbiology, 2017
The Western honey bee (Apis mellifera) is widely used as commercial pollinator in worldwide agriculture and, therefore, plays an important role in global food security.
Sebastian Gisder   +5 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Apis iridescent virus and “clustering disease” of Apis cerana

open access: yesJournal of Invertebrate Pathology, 1978
Abstract Apis iridescent virus was plentiful in each of several samples of adult individuals of Apis cerana from sick colonies in Kashmir and Northern India. Almost every bee, of those examined individually, was infected with the virus, which caused an easily detectable iridescence in the fat body and most other internal organs.
Bailey, L., Ball, B. V.
openaire   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Varroasis y mécanismos de defensa de la abeja melífera (Apis mellifera)

open access: yesRevista de Producción Animal, 2019
Antecedentes: La abeja melífera se encuentra amenazada por varios factores que provocan lo que hoy en día se conoce a nivel mundial como el Síndrome de Colapso de las colmenas, entre los cuales destaca la presencia del ácaro Varroa destructor.
Diego Armando Masaquiza Moposita   +3 more
doaj  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Governify for APIs: SLA-driven ecosystem for API governance

open access: yesProceedings of the 2019 27th ACM Joint Meeting on European Software Engineering Conference and Symposium on the Foundations of Software Engineering, 2019
As software architecture design is evolving to a microservice paradigm, RESTful APIs are being established as the preferred choice to build applications. In such a scenario, there is a shift towards a growing market of APIs where providers offer different service levels with tailored limitations typically based on the cost.
Antonio Gamez-Diaz   +2 more
openaire   +3 more sources

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