Results 61 to 70 of about 48,364 (325)

Unexpected excessive apixaban exposure: case report of a patient with polymorphisms of multiple apixaban elimination pathways

open access: yesBMC Pharmacology and Toxicology, 2019
Background Apixaban effectively lowers the risk of ischemic stroke and systemic embolism in patients with non-valvular atrial fibrillation. Systemic exposure to a given apixaban dose depends on multiple clearance pathways.
Andrea Huppertz   +9 more
doaj   +1 more source

Extended thromboprophylaxis with betrixaban in acutely ill medical patients [PDF]

open access: yes, 2016
BACKGROUND: Patients with acute medical illnesses are at prolonged risk for venous thrombosis. However, the appropriate duration of thromboprophylaxis remains unknown.
. Lodigiani, M   +18 more
core   +1 more source

Apixaban Versus Rivaroxaban in Patients With Atrial Fibrillation and Valvular Heart Disease

open access: yesAnnals of Internal Medicine, 2022
BACKGROUND Although apixaban and rivaroxaban are commonly used in patients with atrial fibrillation (AF) and valvular heart disease (VHD), there is limited evidence comparing the 2 drugs in these patients.
G. Dawwas   +4 more
semanticscholar   +1 more source

Mechanistic Basis for the Differential Effects of Rivaroxaban and Apixaban on Global Tests of Coagulation

open access: yesTH Open, 2018
Rivaroxaban and apixaban are both small molecules that reversibly inhibit factor Xa. Compared with rivaroxaban, apixaban has minimal effects on the prothrombin time and activated partial thromboplastin time.
Paul Y. Kim   +7 more
doaj   +1 more source

Carbamazepine Induction Impacting Apixaban Concentrations: A Case ReportNovel Teaching Points

open access: yesCJC Open, 2020
Avoidance of apixaban with carbamazepine (CBZ) is recommended owing to an anticipated reduction in apixaban concentration, although this drug interaction is poorly described. We report a case wherein apixaban concentration was measured before and 2 weeks
Tammy J. Bungard, BSP, PharmD   +1 more
doaj   +1 more source

Role of rivaroxaban in the management of atrial fibrillation: insights from clinical practice. [PDF]

open access: yes, 2018
© 2018 Vimalesvaran et al. This work is published and licensed by Dove Medical Press Limited.Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, and it leads to significant morbidity and mortality, predominantly from ischemic stroke.
Dockrill, Seth J   +2 more
core   +3 more sources

Anticoagulation in COVID-19: Effect of Enoxaparin, Heparin, and Apixaban on Mortality

open access: yesThrombosis and Haemostasis, 2020
Background Mortality in coronavirus disease of 2019 (COVID-19) is associated with increases in prothrombotic parameters, particularly D-dimer levels. Anticoagulation has been proposed as therapy to decrease mortality, often adjusted for illness severity.
H. Billett   +11 more
semanticscholar   +1 more source

Apixaban versus Warfarin for Treatment of Venous Thromboembolism in Patients Receiving Long-Term Dialysis

open access: yesAmerican Society of Nephrology. Clinical Journal, 2022
Visual Abstract Background and objectives The association of apixaban compared with warfarin for the treatment of venous thromboembolism in patients receiving maintenance dialysis is not well studied.
J. Wetmore   +5 more
semanticscholar   +1 more source

Coagulation and anticoagulation in idiopathic pulmonary fibrosis [PDF]

open access: yes, 2015
Idiopathic pulmonary fibrosis (IPF) is an incurable, progressive interstitial lung disease with a prognosis that is worse than that of many cancers. Epidemiological studies have demonstrated a link between IPF and thrombotic vascular events.
Crooks, Michael G., Hart, Simon P.
core   +3 more sources

D-dimer and reduced-dose apixaban for extended treatment after unprovoked venous thromboembolism: the Apidulcis study

open access: yesBlood Advances, 2022
Key Points • D-dimer testing may help to decide on extended treatment after VTE; this was never assessed since DOACs are available.• Exceedingly more outcomes in patients off anticoagulation for negative D-dimer than in those receiving apixaban for ...
G. Palareti   +24 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy