Results 61 to 70 of about 25,219 (211)

Accidental apixaban intoxication in a 23-month-old child: a case report

open access: yesBMC Pediatrics, 2020
Background Direct oral anticoagulants, such as apixaban, are increasingly used in everyday practice in order to treat or prevent thromboembolic diseases. To date, there is no available data about apixaban pharmacokinetics in children, and no intoxication
Manon Launay   +4 more
doaj   +1 more source

Anatomical Predictors of Optimal Cryoballoon Size Selection: A Prospective Comparison of 28 mm Versus 31 mm Size‐Adjustable Balloon Modes

open access: yesJournal of Arrhythmia, Volume 42, Issue 2, April 2026.
The 31 mm POLARx FIT cryoballoon achieves significantly higher complete pulmonary vein occlusion rates than the 28 mm mode, particularly in superior veins. Larger PV diameter and higher ovality index independently predict incomplete occlusion, supporting pre‐procedural CT‐based anatomical assessment for individualized balloon size selection.
Reisuke Yoshizawa   +12 more
wiley   +1 more source

Measuring Direct Oral Anticoagulant (DOAC) Levels: Applications, Limitations, and Future Directions

open access: yesInternational Journal of Laboratory Hematology, Volume 48, Issue 2, Page 250-258, April 2026.
ABSTRACT Introduction There are important challenges with the measurement and interpretation of direct oral anticoagulant (DOAC) anticoagulant effect including a lack of therapeutic ranges, inaccuracy of routinely available coagulation assays, lack of established thresholds for clinically significant effect, and uncertainty about how to apply the ...
Siraj Mithoowani   +2 more
wiley   +1 more source

A randomized direct comparison of the pharmacokinetics and pharmacodynamics of apixaban and rivaroxaban

open access: yesClinical Pharmacology: Advances and Applications, 2014
Charles Frost,1 Yan Song,1 Yu Chen Barrett,1 Jessie Wang,2 Janice Pursley,3 Rebecca A Boyd,4 Frank LaCreta1 1Exploratory Clinical and Translational Research, 2Exploratory Development Global Biometric Sciences, 3Analytical and Bioanalytical Development ...
Frost C   +6 more
doaj  

Acute severe renal failure in a patient receiving apixaban: a case report

open access: yesItalian Journal of Medicine
Because there is little clinical experience with apixaban in patients with severe renal impairment and non-valvular atrial fibrillation, the European Medicines Agency does not advise using it to prevent strokes in these patients.
Attilia Maria Pizzini   +3 more
doaj   +1 more source

A Delicate Balance

open access: yes
Journal of the American Geriatrics Society, EarlyView.
Ami Schattner
wiley   +1 more source

Risks of thrombosis and hemorrhage in concurrent use of anticoagulants and potential interacting prostate cancer agents

open access: yesCancer, Volume 132, Issue 6, 15 March 2026.
Abstract Background Pharmacokinetic studies suggest that specific prostate cancer therapies may alter the metabolism of direct oral anticoagulants (DOACs), leading to elevated risks of thrombosis or bleeding. Methods To assess the risk of thrombosis or bleeding, population‐based, retrospective, parallel analyses were conducted in Ontario and Alberta ...
Tzu‐Fei Wang   +10 more
wiley   +1 more source

Therapeutic Dilemmas in Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis: Diffuse Alveolar Hemorrhage and Venous Thromboembolism

open access: yesACR Open Rheumatology, Volume 8, Issue 3, March 2026.
Objective Diffuse alveolar hemorrhage (DAH) is a life‐threatening presentation of antineutrophil cytoplasmic antibody–associated vasculitis (AAV). Patients with AAV are at an increased risk of venous thromboembolic events (VTEs). These manifestations can co‐occur; however, the prognosis and management of these patients are poorly understood. Methods In
Elif D. Ediboglu   +5 more
wiley   +1 more source

Safety of anticoagulation with apixaban following acute traumatic brain injury: A case series

open access: yesWorld Neurosurgery: X
Background: The rise in traumatic brain injuries (TBI) among geriatric patients, often using direct oral anticoagulants (DOACs), underscores the urgency to explore safe resumption of these medications post-injury.
Abhishek R. Mogili   +8 more
doaj   +1 more source

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