Results 41 to 50 of about 345,333 (344)

Proposed protocol for treatment of severe periodontitis without platelet transfusion in patients with aplastic anemia: a case report

Journal of Medical Case Reports, 2021
Background Aplastic anemia is an intractable disease characterized by pancytopenia, susceptibility to infection, and difficulty in achieving hemostasis.
Satoru Morikawa, Kazuya Watanabe, Satoshi Usuda, Yoko Miyashita, Taneaki Nakagawa   +4 more
doaj   +1 more source

A plasma microRNA signature as a biomarker for acquired aplastic anemia

Haematologica, 2017
Aplastic anemia is an acquired bone marrow failure characterized by marrow hypoplasia, a paucity of hematopoietic stem and progenitor cells, and pancytopenia of the peripheral blood, due to immune attack on the bone marrow.
Kohei Hosokawa, Sachiko Kajigaya, Xingmin Feng, Marie J. Desierto, Maria del Pilar Fernandez Ibanez, Olga Rios, Barbara Weinstein, Phillip Scheinberg, Danielle M. Townsley, Neal S. Young   +9 more
doaj   +1 more source

Invasive bacterial infections in Gambians with sickle cell anaemia in an era of widespread Pneumococcal and Haemophilus influenzae type B vaccination [PDF]

, 2016
Background: There is relatively little data on the aetiology of bacterial infections in patients with sickle cell anaemia (SCA) in West Africa, and no data from countries that have implemented conjugate vaccines against both Streptococcus pneumoniae and ...
Anderson, ST, Bah, G, Cunnington, A, Darboe, S, Lawal, B, Soothill, G   +5 more
core   +1 more source

Aplastic anemia associated to systemic lupus erythematosus in an AIDS patient: a case report

Revista Brasileira de Hematologia e Hemoterapia, 2013
Aplastic anemia is a bone marrow failure syndrome characterized by peripheral cytopenias and hypocellular bone marrow. Although aplastic anemia is idiopathic in most cases, rheumatic diseases such as systemic lupus erythematosus are recognized as causes ...
Leonardo Rodrigues de Oliveira, Thais Camargos Ferreira, Fernando de Freitas Neves, Antonio Carlos de Oliveira Meneses   +3 more
doaj   +1 more source

Management of Aplastic Anemia in Pregnancy: A Case Report

Indonesian Journal of Obstetrics and Gynecology, 2020
Aplastic anemia was first recognized by Ehrlich in 1888, although the pathogenesis of aplastic anemia has remained elusive. Aplastic anemia is a subtype of anemia characterized by pancytopenia and a hypocellular bone marrow which are the risk factor can ...
Suskhan Djusad, Yoarva Malano
doaj   +1 more source

Treatment optimization and genomic outcomes in refractory severe aplastic anemia treated with eltrombopag.

Blood, 2019
Eltrombopag (EPAG) received approval from the US Food and Drug Administration for the treatment of refractory severe aplastic anemia (rSAA) based on treatment of 43 patients with doses escalating from 50 to 150 mg daily for 12 weeks.
T. Winkler, Xing Fan, J. Cooper, R. Desmond, David J. Young, D. Townsley, P. Scheinberg, Sophia Grasmeder, A. Larochelle, M. Desierto, Janet Valdez, J. Lotter, Colin O. Wu, R. Shalhoub, K. Calvo, N. Young, C. Dunbar   +16 more
semanticscholar   +1 more source

Myelodysplastic syndrome evolving from aplastic anemia treated with immunosuppressive therapy: efficacy of hematopoietic stem cell transplantation

Haematologica, 2014
A proportion of patients with aplastic anemia who are treated with immunosuppressive therapy develop clonal hematologic disorders, including post-aplastic anemia myelodysplastic syndrome.
Sung-Yong Kim, Jennifer Le Rademacher, Joseph H. Antin, Paolo Anderlini, Mouhab Ayas, Minoo Battiwalla, Jeanette Carreras, Joanne Kurtzberg, Ryotaro Nakamura, Mary Eapen, H. Joachim Deeg   +10 more
doaj   +1 more source

THPO gene variants in patients with acquired aplastic anemia

Hematology, Transfusion and Cell Therapy, 2018
Background: Human aplastic anemia is a hematologic disease characterized by low peripheral blood cell counts associated with reduced numbers of hematopoietic stem and progenitor cells and a hypocellular bone marrow.
Pedro Henrique Padilha, Gustavo Borges, Barbara Amélia Santana, Larissa Alessandra Medeiros, Samir Kanaan Nabhan, Ricardo Pasquini, Flavia Sacilotto Donaires, Rodrigo Tocantins Calado   +7 more
doaj   +1 more source

Severe retinal hemorrhages at various levels with a serous retinal detachment in a pediatric patient with aplastic anemia–A case report

Frontiers in Medicine, 2023
BackgroundAplastic anemia can cause ophthalmic abnormalities in patients. Vision loss in a child with aplastic anemia due to massive retinal hemorrhages at various levels is rare.Case presentationA pediatric patient with aplastic anemia presented with ...
Xiaoshuang Jiang, Mengxi Shen, Licong Liang, Philip J. Rosenfeld, Fang Lu   +4 more
doaj   +1 more source

Diagnosis and treatment of pediatric acquired aplastic anemia (AAA): An initial survey of the North American Pediatric Aplastic Anemia Consortium (NAPAAC) [PDF]

, 2013
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/106711/1/pbc24875 ...
Bennett, Carolyn, Bertuch, Alison, Bessler, Monica, Coates, Thomas, Corey, Seth, Dror, Yigal, Huang, James, Lipton, Jeffrey, Olson, Timothy S., Reiss, Ulrike M., Rogers, Zora R., Shimamura, Akiko, Sieff, Colin, Vlachos, Adrianna, Walkovich, Kelly, Wang, Winfred, Williams, David A.   +16 more
core   +1 more source