Results 61 to 70 of about 345,333 (344)

Hepatitis-associated aplastic anemia from workout supplement: Rare but potentially fatal entity

SAGE Open Medical Case Reports, 2020
Hepatitis-associated aplastic anemia (HAAA) is a rare clinical syndrome characterized by bone marrow failure 1–3 months after development of hepatitis. Untreated, hepatitis-associated aplastic anemia has poor outcome and the mainstay of treatment remains
Sanjog Bastola, Ojbindra Kc, Sumesh Khanal, Alexandra Halalau   +3 more
doaj   +1 more source

Aplastic anemia and severe pancytopenia during treatment with peg-interferon, ribavirin and telaprevir for chronic hepatitis C [PDF]

, 2016
Telaprevir and Boceprevir are the first direct acting antivirals approved for chronic hepatitis C in combination with peg-interferon alfa and ribavirin.
Broquetas, Teresa, Calleja Panero, José Luis, Campillo, Ana, Carrion, José A., Forns, Xavier, Lens Garcia, Sabela, Londoño Hurtado, María Carlota, Mariño, Zoe, Perello, Chrostoe, Revilla, Juan de la, Sánchez Tapias, José M. (José María), Urbano Ispizua, Álvaro   +11 more
core   +1 more source

Evolving Real‐World Data and Evidence Use for New Drugs and Regenerative Medical Products Approvals in Japan—An Analysis of the 6‐Year Trend

Clinical Pharmacology &Therapeutics, EarlyView.
Several regulatory initiatives have been made to clarify the acceptability and requirements of real‐world data and real‐world evidence (RWD/E) for the benefit/risk assessment of new medical products in Japan. The objectives of this review were to characterize the use of RWD/E in regulatory applications of new medical products and to describe the ...
Suguru Okami, Kako Shimotsumagari, Yasunari Sadatsuki   +2 more
wiley   +1 more source

Fatigue, symptom burden, and health‐related quality of life in patients with myelodysplastic syndrome, aplastic anemia, and paroxysmal nocturnal hemoglobinuria

Cancer Medicine, 2019
Fatigue is distressing and affects quality of life (QoL) among patients with myelodysplastic syndrome (MDS), aplastic anemia (AA), and paroxysmal nocturnal hemoglobinuria (PNH).
C. Escalante, Stephanie Chisolm, Juhee Song, Marsha N. Richardson, Ellen J Salkeld, E. Aoki, G. Garcia-Manero   +6 more
semanticscholar   +1 more source

FIGO good practice recommendations on anemia in pregnancy, to reduce the incidence and impact of postpartum hemorrhage (PPH)

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Anemia affects 32 million pregnant women globally, contributing annually to more than 115 000 maternal deaths and 591 000 perinatal deaths worldwide. Low‐ and middle‐income countries (LMICs) bear the highest burden of anemia in pregnancy, with nearly 50% of affected pregnant women. It is now 2025, which is WHO's target year for a 50% reduction
Akaninyene E. Ubom, Ferdousi Begum, Diana Ramasauskaite, Albaro J. Nieto‐Calvache, Monica Oguttu, Inês Nunes, Zechariah J. Malel, Jolly Beyeza‐Kashesya, Alison Wright, on behalf of the FIGO Committee on Childbirth and Postpartum Hemorrhage   +9 more
wiley   +1 more source

Bone marrow mesenchymal stem cells from patients with aplastic anemia maintain functional and immune properties and do not contribute to the pathogenesis of the disease

Haematologica, 2014
Aplastic anemia is a life-threatening bone marrow failure disorder characterized by peripheral pancytopenia and marrow hypoplasia. The majority of cases of aplastic anemia remain idiopathic, although hematopoietic stem cell deficiency and impaired immune
Clara Bueno, Mar Roldan, Eduardo Anguita, Damia Romero-Moya, Beatriz Martín-Antonio, Michael Rosu-Myles, Consuelo del Cañizo, Francisco Campos, Regina García, Maite Gómez-Casares, Jose Luis Fuster, Manuel Jurado, Mario Delgado, Pablo Menendez   +13 more
doaj   +1 more source

Oncologic Emergencies: Immune-Based Cancer Therapies and Complications [PDF]

, 2020
Cancer therapies have undergone several recent advancements. Current cancer treatments include immune-based therapies comprised of checkpoint inhibitors, and adoptive immunotherapy; each treatment has the potential for complications that differ from ...
Brém, Elizabeth, Koyfman, Alex, Long, Brit Jeffrey   +2 more
core  

Hepatitis-Associated Aplastic Anemia

Hematology/Oncology and Stem Cell Therapy, 2022
Hepatitis-associated aplastic anemia (HAAA) is a rare illness, characterized by onset of pancytopenia with a hypoplastic bone marrow that traditionally occurs within 6 months of an increase in serum aminotransferases. HAAA is observed in 1% to 5% of all newly diagnosed cases of acquired aplastic anemia.
Alshaibani A., Dufour C., Risitano A., de Latour R., Aljurf M.   +4 more
openaire   +5 more sources

Electrochemical detection of chloramphenicol in feed and soil matrices using SPCE‐N‐GQD sensors for on‐site screening applications

Journal of the Chinese Chemical Society, EarlyView.
Nitrogen‐doped graphene quantum dots (N‐GQDs) were anchored onto screen‐printed carbon electrodes to selectively preconcentrate chloramphenicol (CAP). Enhanced electrochemical profiles and pH‐sensitive responses—highlight NGQD‐facilitated charge‐transfer behavior, reinforcing its potential in CAP monitoring within livestock feed and broader ...
Hwei‐yan Tsai, Chun‐Yen Liao, Yu‐Yun Cho, Chien‐Hong Chen, Jia‐Yun Lyu, Chwan‐Bor Fuh   +5 more
wiley   +1 more source

Improved Outcome of a Reduced Toxicity-Fludarabine, Cyclophosphamide, plus Antithymocyte Globulin Conditioning Regimen for Unrelated Donor Transplantation in Severe Aplastic Anemia: Comparison of 2 Multicenter Prospective Studies [PDF]

, 2016
Hematopoietic stem cell transplantation (HSCT) is a curative therapy for severe aplastic anemia (SAA); however, the optimal conditioning regimen for HSCT with an unrelated donor has not yet been defined.
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core   +1 more source