Results 71 to 80 of about 339,316 (310)
Diagnosis of leukemia and aplastic anemia by the bone marrow culture [PDF]
, 1956 1) As the boundary of the outgrowth zone of the bone marrow culture is sharply defined from the surrounding area and the cellular density becomes very high in leukemia, diagnosis can be made with ease and certainty.
Hattori, Yoshiyuki +2 more
core +1 more source
Aplastic anemia: Etiology, molecular pathogenesis, and emerging concepts
European Journal of Haematology, 2018 Aplastic anemia (AA) is rare disorder of bone marrow failure which if severe and not appropriately treated is highly fatal. AA is characterized by morphologic marrow features, namely hypocellularity, and resultant peripheral cytopenias.
R. Shallis, R. Ahmad, A. Zeidan
semanticscholar +1 more source
Med Research, EarlyView.ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin +8 more
wiley +1 more source
Improved Outcome of a Reduced Toxicity-Fludarabine, Cyclophosphamide, plus Antithymocyte Globulin Conditioning Regimen for Unrelated Donor Transplantation in Severe Aplastic Anemia: Comparison of 2 Multicenter Prospective Studies [PDF]
, 2016 Hematopoietic stem cell transplantation (HSCT) is a curative therapy for severe aplastic anemia (SAA); however, the optimal conditioning regimen for HSCT with an unrelated donor has not yet been defined.
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Food safety practices are widely recommended for pediatric patients with cancer or undergoing hematopoietic stem cell transplantation (HCT) to mitigate foodborne infectious risks. However, specific measures, such as the neutropenic diet (ND) or low‐microbial diet, lack robust evidence and are inconsistently implemented across ...
Davide Leardini +28 more
wiley +1 more source
Anemia in Antiretroviral Naïve HIV/AIDS Patients: A Study from Eastern India [PDF]
, 2012 Background: Hematological manifestations are common throughout the course of HIV infection. Impact of anemia is the most significant among them. The present study was undertaken to evaluate the etiologies underlying anemia in HIV/AIDS. Methods This was a
Banerjee, A +6 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Endothelial damage may play a key role in several non‐infectious toxicities following hematopoietic stem cell transplantation (HSCT). We explored damage to the endothelial glycocalyx in 113 children undergoing HSCT by measuring syndecan‐1 plasma levels.
Denise Elbæk Horan +6 more
wiley +1 more source
Health Science Reports, 2023 Scurvy is a rare nutritional deficiency disease which is less likely to be suspected and it mostly lead to delayed diagnosis. It can present with features which can mislead clinicians to misdiagnose the condition as leukemia or aplastic anemia.
Harold L. Mashauri
doaj +1 more source
Current Treatment Patterns of Aplastic Anemia in China: A Prospective Cohort Registry Study
Acta Haematologica, 2019 Aplastic anemia (AA) is a hematologic disease characterized by pancytopenia and hypocellular bone marrow, potentially leading to chronic anemia, hemorrhage, and infection.
Xiao-Fan Zhu +21 more
semanticscholar +1 more source
hTERT Increases TRF2 to Induce Telomere Compaction and Extend Cell Replicative Lifespan
Aging Cell, EarlyView.In contrast to the dogma that a subset of short telomeres initiates senescence, hTERT variants unable to maintain telomere length block senescence by stabilizing TRF2 via inhibiting upstream E3 ubiquitin ligases. This noncanonical hTERT function also compacts telomeres and blocks senescence‐associated DNA damage signaling. Cancer cells expressing hTERT
Nancy Adam +15 more
wiley +1 more source