Results 111 to 120 of about 114,772,772 (250)

Butyrate stimulates the secretion of apolipoprotein (apo) A-I and apo B100 by the human hepatoma cell line Hep G2. Induction of apo A-I mRNA with no change of apo B100 mRNA

, 1991
Addition of sodium butyrate to the culture medium of the human hepatoma cell line Hep G2 resulted in a time- and dose-dependent increase in the secretion of apolipoprotein A-I (apo A-I) and apolipoprotein B100 (apo B100).
Kaptein, A., Roodenburg, L., Princen, H.M.G.   +2 more
core  

Caspase 8 activation independent of Fas (CD95/APO-1) signaling may mediate killing of B-chronic lymphocytic leukemia cells by cytotoxic drugs or gamma radiation. [PDF]

, 2001
Ligation of the cell-surface Fas molecule by its ligand (Fas-L) or agonistic anti-Fas monoclonal antibodies results in the cleavage and activation of the cysteine protease procaspase 8 followed by the activation of procaspase 3 and by apoptosis.
Jones, DT, Ganeshaguru, K, Mehta, AB, Prentice, HG, Virchis, AE, Lowdell, MW, Wickremasinghe, RG, Hoffbrand, AV, Folarin, NI   +8 more
core  

Modulation of the TGF‐β/Smad Signaling Pathway by a Bioactive Oxidized Polygonati Rhizoma Polysaccharide Crosslinked Chitosan Hydrogel as Therapeutic Carrier for Parkinson's Disease Treatment

Advanced Science, EarlyView.
An injectable, self‐healing COPRP hydrogel integrates structurally defined oxidized Polygonati rhizoma polysaccharide with carboxymethyl chitosan through dynamic Schiff‐base crosslinking. The bioactive matrix scavenges reactive oxygen species, suppresses neuroinflammation, protects dopaminergic neurons, and supports sustained levodopa release.
Peng Dai, Jikuang Zhao, Chang Xue, Kailei Xu, Liang Yong, Zhuangwei Zhang, Yi Huang, Jianwei Shuai, Xianzhen Chen, Sheng Nie, Junpeng Xu   +10 more
wiley   +1 more source

Índice apo B/apo A-I e predição de risco cardiovascular Apo B/apo A-I ratio and cardiovascular risk prediction

Arquivos Brasileiros de Cardiologia, 2007
Luciana Moreira Lima, Maria das Graças Carvalho, Marinez Oliveira Sousa   +2 more
doaj   +1 more source

Characterization of apo(a) polymorphism by a modified immunoblotting technique in an italian population sample

, 1993
Apo(a), the specific lipoprotein(a) (Lp(a)) apolipoprotein, is characterized by different isoforms (from 6 to 11 on SDS-PAGE) encoded by a system of autosomal codominant alleles.
Geroldi D., Fratino P., Bonetti G., Gazzaruso C., Caprioli A., Buscaglia P., Bellotti V.   +6 more
core   +1 more source

Astrocytes Coordinate Neurovascular Coupling During Prolonged Sensory Demand via AQP4/TRPA1/BEST1/D‐Serine Signaling

Advanced Science, EarlyView.
Neuronal activation leads to astrocytic transient volume changes, activating transient receptor potential ankyrin 1 (TRPA1) channels, leading to Ca2+ influx. Activation of TRPA1 causes the release of D‐serine through BEST1. Finally, the augmented extracellular levels of D‐serine boost neuronal activity by binding GluN1‐containing NMDARs, leading to CBV
Kayoung Han, Minwoo Wendy Jang, Taeyoung Park, Ki Jung Kim, Victor James Drew, Sunpil Kim, Tai Young Kim, Mingu Gordon Park, Myeongju Kim, Seung Won Chung, Minah Suh, C. Justin Lee   +11 more
wiley   +1 more source

Rapport annuel /

, 2002
2001/2002-Titre de ...
Vitrine APO
core   +1 more source

Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states.

, 2013
ABCB10 is one of the three ATP-binding cassette (ABC) transporters found in the inner membrane of mitochondria. In mammals ABCB10 is essential for erythropoiesis, and for protection of mitochondria against oxidative stress.
Sansom, MS, Gileadi, O., Li, Q., Yang, J., von Delft, F., Bullock, A.N., Barr, A. J., Shrestha, L, Marsden, BD, Ross, J, Ross, J., Sansom, M. S. P., Shintre, CA, Yang, J, Carpenter, E. P., Carpenter, E.P., Kim, J-I., Barr, A.J., Burgess-Brown, N.A., Burgess-Brown, Nicola, Berridge, G, von Delft, Frank, Goubin, S, Shintre, C. A., Berridge, G., Marsden, B., Edwards, AM, Stansfeld, P.J., Sansom, M.S.P., Burgess-Brown, N. A., Bullock, Alexander, Bountra, C., Gileadi, Opher, Shrestha, L., Shintre, C.A., Pike, AC, Goubin, S., Barr, AJ, Kim, JI, Bullock, A. N., Pike, A. C. W., Kim, J.I., Pike, A.C.W., Bountra, Charanjit, Edwards, A.M., Carpenter, Elizabeth, Stansfeld, PJ, Stansfeld, Phillip J., Edwards, A. M., Marsden, B. D., Li, Q   +50 more
core   +1 more source

Zinc Fingers as Programmable Metalloprotein Scaffolds for Altering Pathogenic Biomolecular Phase Transitions

Advanced Science, EarlyView.
Modular zinc finger (ZF) metalloproteins function as programmable biomolecular scaffolds that modulate pathogenic amyloid assembly. Through direct protein–protein interactions, ZF arrays alter amyloid phase behavior and redirect β‐sheet fibrillization toward nontoxic aggregates.
Seongmin Park, Yunha Hwang, Jimin Kwak, Yuxi Lin, Hye‐Yeon Park, Eunju Nam, Jiyeon Han, Soyeon Park, Hyunyong Kim, Ju‐Eun Kim, Hyun Goo Kang, Jiyong Park, Young‐Ho Lee, Kyoung‐Shim Kim, Chul‐Ho Lee, Seung Jae Lee, Mi Hee Lim   +16 more
wiley   +1 more source

Role of vitamin D3 level and Apo-B/Apo-A1 ratio in patients with unstable angina in Kerbala province, Iraq

Journal of Contemporary Medical Sciences, 2017
Objectives Vitamin D deficiency may be responsible for endothelial dysfunction which in turn affects the onset and progression of coronary artery disease and its risk factors.
Fadhil Jawad Al-Tu’ma, Zahraa Mohsen Mohammed, Haidar Hussein Al-Sarraf   +2 more
doaj