Results 21 to 30 of about 95,854 (268)

A PANEL OF GENETIC MARKERS FOR ANALYZING THE RISK OF LONG-TERM ADVERSE PROGNOSIS OF CARDIOVASCULAR DISEASES

open access: yesАтеросклероз, 2018
Aim: to form a panel of genetic markers for analyzing the risk of long-term adverse prognosis of cardiovascular diseases in Russia population. Material and methods.
E. V. Shakhtshneider   +7 more
doaj   +1 more source

RNA-Seq Mouse Brain Regions Expression Data Analysis: Focus on ApoE Functional Network

open access: yesJournal of Integrative Bioinformatics, 2017
ApoE expression status was proved to be a highly specific marker of energy metabolism rate in the brain. Along with its neighbor, Translocase of Outer Mitochondrial Membrane 40 kDa (TOMM40) which is involved in mitochondrial metabolism, the corresponding
Babenko Vladimir N.   +2 more
doaj   +1 more source

Microbiota and Alzheimer's disease: Toward new clinical approaches [PDF]

open access: yesMedicinski Podmladak
Alzheimer’s disease (AD) is now viewed as a systemic disorder in which genetics, the gut microbiome and immune dysregulation converge to accelerate amyloid-β (Aβ) and tau pathology. Genetic studies have identified 70 risk loci. The strongest AD risk loci
Đokić Jelena, Dinić Miroslav
doaj   +1 more source

APOE4 Status and cognitive function in middle-aged and elderly people

open access: yesBalkan Journal of Medical Genetics, 2023
APOE is one of the prominent genes involved in the increased risk of developing Alzheimer’s disease, but its effect on cognition in patients who are not yet diagnosed with dementia or mild cognitive impairment is relatively understudied.
Pavel N.A.   +4 more
doaj   +1 more source

Association Analysis of Polymorphisms in BIN1, MC1R, STARD6 and PVRL2 with Mild Cognitive Impairment in Elderly Carrying APOE ϵ4 Allele

open access: yesNeuropsychiatric Disease and Treatment, 2021
Yue Wu,1,* Jiajun Yin,2,* Bixiu Yang,3 Li Tang,4 Wei Feng,5 Xiaowei Liu,1 Xingfu Zhao,1 Zaohuo Cheng1 1Department of Geriatric Psychiatry, The Affiliated Wuxi Mental Health Center with Nanjing Medical University, Wuxi, Jiangsu Province, People’s ...
Wu Y   +7 more
doaj  

Giresun İlinde FV, FXIII, ACE, ApoE Gen Varyantlarının Prevelansı ve Koroner Arter Hastalığı Profiline Etkilerinin Araştırılması

open access: yesİstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi, 2019
Amaç: Ateroskleroz kaynaklı Koroner Arter Hastalığı (KAH), multifaktöriyel ve poligenik kompleks bir hastalıktır. Son yıllarda yapılan çalışmalarda KAH ile ilişkili bazı genetik varyantlar öne çıkmıştır.
Erhan Teker   +3 more
doaj   +1 more source

APOE genetic variants and apoE, miR-107 and miR-650 levels in Alzheimer’s disease

open access: yesFolia Neuropathologica, 2019
Alzheimer’s disease (AD) is a progressive neurodegenerative dementia in adults. Pathogenesis of AD depends on various factors, including APOE genetic variants, apolipoprotein E (apoE) phenotype and oxidative stress, which may promote both DNA and RNA ...
Michal Prendecki   +7 more
doaj   +1 more source

The role of the KIBRA and APOE genes in developing spatial abilities in humans

open access: yesВавиловский журнал генетики и селекции, 2022
In the contemporary high-tech society, spatial abilities predict individual life and professional success, especially in the STEM (Science, Technology, Engineering, and Mathematics) disciplines.
A. V. Kazantseva   +8 more
doaj   +1 more source

Ferroptosis-Related APOE, BCL3 and ALOX5AP Gene Polymorphisms are Associated with the Risk of Thyroid Cancer

open access: yesPharmacogenomics and Personalized Medicine, 2022
Zhifu Xiao,1,* Haixia Zhao2,* 1Department of Thyroid Surgery, Shanxi Provincial People’s Hospital, Taiyuan, Shanxi, 030012, People’s Republic of China; 2Central Lab, General Hospital of Taiyuan Iron and Steel Group, Taiyuan, Shanxi, 030003 ...
Xiao Z, Zhao H
doaj  

Polymorphism of PPARG (P12A), APOA1 (G75A), and APOE (C112A and A158C) Genes in Children with Obesity and Arterial Hypertension: A Case-Control Study

open access: yesВопросы современной педиатрии, 2018
Background. The genetic nature of a comorbid development of obesity and arterial hypertension (AH) in children is poorly studied. In this regard, it is important to study genes, the polymorphism of which is associated with disturbances in both metabolic ...
Olga P. Kovtun   +1 more
doaj   +1 more source

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