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Scientific Reports, 2023 Although beta-amyloid (Aβ) and phosphorylated tau remain the preferred targets for disease-modifying treatments (DMT) against Alzheimer’s disease (AD), part of the pathophysiological mechanisms of cognitive impairment are related to neuroinflammation and
Xavier Morató +46 more
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Alzheimer’s Research & Therapy, 2022 Background FACEmemory® is the first computerized, self-administered verbal episodic memory test with voice recognition. It can be conducted under minimal supervision and contains an automatic scoring system to avoid administrator errors.
Montserrat Alegret +24 more
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ACE2 and Diabetes: ACE of ACEs? [PDF]
Diabetes, 2010 The mechanisms involved in the development of diabetes and its complications are complex, with a long list of potential derangements on different pathways (1,2). In this commentary, we discuss angiotensin converting enzyme 2 (ACE2) as a potential participant in the development of both islet β-cell insufficiency early on and in the development of ...
Batlle, Daniel +2 more
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Scientific Reports, 2022 Optical coherence tomography angiography (OCT-A) allows the detection of retinal vessel density (VD) loss, which is a reflection of brain vascular pathology. We aimed to investigate differences in macular VD in the superficial plexus in a large cohort of
Marta Marquié +25 more
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Effects of Sub therapeutic Doses of ACE-I in Improving insulin sensitivity in Type II DM Patients [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2014 Diabetes mellitus (DM) is a complex, multifactorial and heterogeneous group of disorders characterized by endogenous insulin deficiency and/or insulin resistance.
Nesren Sh. Mohammed +2 more
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Baltic Journal of Health and Physical Activity, 2023 Introduction: This study investigated the differences in ACTN3, ACE and ADRB3 variants in top-level soccer players who entered the Croatian National Team and the ones who did not but played for two best Croatian teams.
Lana Ruzic +2 more
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Interactions of the eNOS and ACE genes and cigarette smoking in chronic obstructive pulmonary disease [PDF]
Journal of Medical Biochemistry, 2023 Background: Chronic obstructive pulmonary disease (COPD) is a complex disorder with unexplained heritability. Interactions of genetic and environmental factors are thought to be crucial in COPD.
Stanković Marija +6 more
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Pharmaceutical Biology, 2020 Context Fruit of Avicennia marina (Forsk.) Vierh. (Acanthaceae) is used as a Chinese herb. Studies have found that it contains marinoid J, a novel phenylethanoid glycoside (PG) compound, but its neuroprotective functions are largely unknown.
Xiang-xi Yi +6 more
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Frontiers in Computational Neuroscience, 2016 Good metaphors can help understanding complex systems. The brain-computer metaphor arguably started when McCulloch and Pitts (1943) put together the idea of an artificial computational neuron with multiple inputs, either inhibitory or excitatory, a single branching output and a threshold for firing, proving that in principle a neural network made of ...
Zanin M. +3 more
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Vitamin D is a strategic blow to coronavirus infection
Медицинский совет, 2021 The world is in the grip of the pandemic of the new viral infection COVID-19. The number of patients around the world is not only not decreasing, but also progressively increasing.
V. V. Salukhov, E. A. Kovalevskaya
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