Results 11 to 20 of about 280,695 (304)

A randomized, open-label clinical trial in mild cognitive impairment with EGb 761 examining blood markers of inflammation and oxidative stress

Scientific Reports, 2023
Although beta-amyloid (Aβ) and phosphorylated tau remain the preferred targets for disease-modifying treatments (DMT) against Alzheimer’s disease (AD), part of the pathophysiological mechanisms of cognitive impairment are related to neuroinflammation and
Xavier Morató, Marta Marquié, Juan Pablo Tartari, Asunción Lafuente, Carla Abdelnour, Montserrat Alegret, Sara Jofresa, Mar Buendía, Ana Pancho, Núria Aguilera, Marta Ibarria, Susana Diego, Rosario Cuevas, Laia Cañada, Anna Calvet, Ester Esteban-De Antonio, Alba Pérez-Cordón, Ángela Sanabria, Itziar de Rojas, Raúl Nuñez-Llaves, Amanda Cano, Adelina Orellana, Laura Montrreal, Pilar Cañabate, Maitée Rosende-Roca, Liliana Vargas, Urszula Bojaryn, Mario Ricciardi, Diana M. Ariton, Ana Espinosa, Gemma Ortega, Nathalia Muñoz, Núria Lleonart, Emilio Alarcón-Martín, Mariola Moreno, Silvia Preckler, Natalia Tantinya, Maribel Ramis, Ana Belen Nogales, Susanna Seguer, Elvira Martín, Vanesa Pytel, Sergi Valero, Miren Gurruchaga, Lluís Tárraga, Agustín Ruiz, Mercè Boada   +46 more
doaj   +1 more source

Differences in macular vessel density in the superficial plexus across cognitive impairment: the NORFACE cohort

Scientific Reports, 2022
Optical coherence tomography angiography (OCT-A) allows the detection of retinal vessel density (VD) loss, which is a reflection of brain vascular pathology. We aimed to investigate differences in macular VD in the superficial plexus in a large cohort of
Marta Marquié, Sergi Valero, Joan Martínez, Emilio Alarcón-Martín, Ainhoa García-Sánchez, Itziar de Rojas, Miguel Castilla-Martí, Luis Castilla-Martí, Isabel Hernández, Maitée Rosende-Roca, Liliana Vargas, Juan Pablo Tartari, Ester Esteban-De Antonio, Urszula Bojaryn, Vanesa Pytel, Leire Narvaiza, Montserrat Alegret, Gemma Ortega, Ana Espinosa, Ángela Sanabria, Alba Pérez-Cordón, Núria Lleonart, Nathalia Muñoz, Lluís Tárraga, Agustín Ruiz, Mercè Boada   +25 more
doaj   +1 more source

ACE2 and Diabetes: ACE of ACEs? [PDF]

Diabetes, 2010
The mechanisms involved in the development of diabetes and its complications are complex, with a long list of potential derangements on different pathways (1,2). In this commentary, we discuss angiotensin converting enzyme 2 (ACE2) as a potential participant in the development of both islet β-cell insufficiency early on and in the development of ...
Batlle, Daniel, Jose Soler, Maria, Ye, Minghao   +2 more
openaire   +2 more sources

Automatized FACEmemory® scoring is related to Alzheimer’s disease phenotype and biomarkers in early-onset mild cognitive impairment: the BIOFACE cohort

Alzheimer’s Research & Therapy, 2022
Background FACEmemory® is the first computerized, self-administered verbal episodic memory test with voice recognition. It can be conducted under minimal supervision and contains an automatic scoring system to avoid administrator errors.
Montserrat Alegret, Oscar Sotolongo-Grau, Ester Esteban de Antonio, Alba Pérez-Cordón, Adelina Orellana, Ana Espinosa, Silvia Gil, Daniel Jiménez, Gemma Ortega, Angela Sanabria, Natalia Roberto, Isabel Hernández, Maitee Rosende-Roca, Juan Pablo Tartari, Emilio Alarcon-Martin, Itziar de Rojas, Laura Montrreal, Xavier Morató, Amanda Cano, Dorene M. Rentz, Lluís Tárraga, Agustín Ruiz, Sergi Valero, Marta Marquié, Mercè Boada   +24 more
doaj   +1 more source

Effects of Sub therapeutic Doses of ACE-I in Improving insulin sensitivity in Type II DM Patients [PDF]

مجلة جامعة الانبار للعلوم الصرفة, 2014
Diabetes mellitus (DM) is a complex, multifactorial and heterogeneous group of disorders characterized by endogenous insulin deficiency and/or insulin resistance.
Nesren Sh. Mohammed, Saad A. Hussain, Isam Noori Ai-Karwi   +2 more
doaj   +1 more source

Differences in ACTN3, ACE, and ADBR3 polymorphisms between Croatian National Team and non-national team elite soccer players

Baltic Journal of Health and Physical Activity, 2023
Introduction: This study investigated the differences in ACTN3, ACE and ADRB3 variants in top-level soccer players who entered the Croatian National Team and the ones who did not but played for two best Croatian teams.
Lana Ruzic , Ivan Radman, Branka R. Matkovic   +2 more
doaj   +1 more source

Interactions of the eNOS and ACE genes and cigarette smoking in chronic obstructive pulmonary disease [PDF]

Journal of Medical Biochemistry, 2023
Background: Chronic obstructive pulmonary disease (COPD) is a complex disorder with unexplained heritability. Interactions of genetic and environmental factors are thought to be crucial in COPD.
Stanković Marija, Đorđević Valentina, Tomović Andrija, Nagorni-Obradović Ljudmila, Petrović-Stanojević Nataša, Kovač Mirjana, Radojković Dragica   +6 more
doaj   +1 more source

EGI-ACE Impact report

, 2023
<p>Discover the profound impact of the project through our comprehensive EGI-ACE Impact Report, showcasing the Key Exploitable Results, Success stories and Impacts on different areas.</p ...
EGI-ACE Consortium
core   +1 more source

A genome-wide search replicates evidence of a quantitative trait locus for circulating angiotensisn l-converting enzyme (ACE) unlinked to the ACE gene [PDF]

, 2008
Background: angiotensin I-converting enzyme (ACE) plays an important role in cardiovascular homeostasis. There is evidence from different ethnic groups that circulating ACE levels are influenced by a quantitative trait locus (QTL) at the ACE gene on ...
Amy Luke, Zhu, Xiaofeng, Xiaofeng Zhu, Terrence E Forrester, Forrester, Terrence E., Nourdine Bouzekri, Cooper, Richard S., Bouzekri Nourdine, Colin A McKenzie, McKenzie, Coiln A., Forrester Terrence E, Zhu Xiaofeng, McKenzie Colin A, Adeyemo, Adebowale A., Luke Amy, Bouzekri, Nourdine, Cooper Richard S, Richard S Cooper, Luke, Amy, Adebowale A Adeyemo, Adeyemo Adebowale A   +20 more
core   +1 more source

Homogeneous assay of rs4343, an ACE I/D proxy, and an analysis in the British Women's Heart and Health Study (BWHHS). [PDF]

, 2008
Current literature suggests that ACE SNP rs4343, ACE 2350A>G in exon 17, T202T, may be the best proxy for the ACE Alu I/D whereas rs4363 and rs4362 may be slightly stronger predictors of ACE levels. Considering reported difficulties in genotyping ACE I/D
Day, Ian N M, Rodriguez, Santiago, Gaunt, Tom R, Gaunt, TR, Huang, S, Lawlor, D, Guthrie, Philip Alexander Isles, Smith, George Davey, Abdollahi, Mohammad Reza, Lawlor, Debbie A, Abdollahi, MR, Ebrahim, S, Guthrie, PAI, Huang, Shuwen, Rodríguez, S, Day, INM, Day, Ian NM, Davey Smith, G, Ebrahim, Shah   +18 more
core   +1 more source