Results 91 to 100 of about 95,854 (268)

Sex Differences in the Association of Simultaneous Decline in Blood Pressure and Decline in Cognition during Aging

open access: yesAnnals of Neurology, EarlyView.
Objective Both high and declining blood pressure (BP) are associated with risk of cognitive decline in older adults, and women have higher rates of hypertension and faster cognitive decline in late‐life. In old age, the relationship between changes in BP and changes in cognition is complex, and although sex differences in cognitive function and decline
Nicholas W. Baumgartner   +4 more
wiley   +1 more source

Diabetes and the Metabolic Syndrome as Drivers of Neurodegeneration: Convergent Mechanisms Linking Peripheral Neuropathy and Dementia

open access: yesAnnals of Neurology, EarlyView.
The metabolic syndrome, a state of progressive metabolic dysfunction, injures the peripheral and central nervous systems, promoting peripheral neuropathy (PN) and cognitive impairment (CI), respectively. We posit PN and CI are connected in the metabolic syndrome framework, built on the premise that neurons, whether in the peripheral or central nervous ...
Masha G. Savelieff   +3 more
wiley   +1 more source

MOLECULAR-GENETICAL MARKERS OF LIPID ABNORMALITIES AND SUDDEN CARDIAC DEATH

open access: yesАтеросклероз, 2017
Sudden cardiac death is one of main problem of modern medicine. Sudden cardiac death is about 50 % of all cardiac deaths. The main part of people who died of sudden cardiac death didn’t have any cardiac illnesses.
A. A. Ivanova
doaj  

Perivascular Spaces as Determinants of Amyloid, Tau, and Vascular Biomarker Progression

open access: yesAnnals of Neurology, EarlyView.
Objective Magnetic resonance imaging (MRI)‐visible enlarged perivascular spaces (PVS) are markers of cerebral small vessel disease (SVD) and aging, processes implicated in both neurodegenerative and cerebrovascular pathologies. However, longitudinal positron emission tomography (PET) studies examining PVS as a mechanism underlying Alzheimer's disease ...
Audrey Low   +11 more
wiley   +1 more source

Some common candidate genes in arterial hypertension and gallstlone disease pathogenesis

open access: yesАтеросклероз, 2014
Gallstone disease (GSD) and arterial hypertension (AH) have many common risk factors – age, overweight, dyslipidemia, low physical activity, diabetes mellitus, in addition, the presence of AH is considered by many authors as a risk factor for GSD ...
M. S. Lebedeva   +3 more
doaj  

Corpus-based analysis on the use of 'this' and 'it'

open access: yes, 2018
Käesoleva bakalaurusetöö “Korpuseanalüüs asesõnade this ja it kasutamisest” teemaks on inglise keelt õppivate eestlaste asesõnade this ja it kasutamist. Analüüsiks oli võetud 2014. aasta Tartu Ülikooli õppijakeele korpus, mis koosnes 127-st tekstist, mis olid inglise keele ja kirjanduse õppe sisseastumiseksami kolmanda küsimuse vastused. Töö eesmärgiks
openaire   +1 more source

Genetic Modifiers of ABCA1 Activity Interact with APOE Isoforms to Mediate Alzheimer's Disease Risk

open access: yesAnnals of Neurology, EarlyView.
Objective ATP‐binding cassette transporter A1 (ABCA1) has been associated with Alzheimer's disease (AD), but the mechanisms by which it impacts disease risk are unknown. ABCA1 is known to bind apolipoprotein E (ApoE) and catalyze apolipoprotein lipidation.
Andrés Peña‐Tauber   +24 more
wiley   +1 more source

Blood Biomarkers of Alzheimer's Disease and Patterns of Structural Brain Changes in the Community

open access: yesAnnals of Neurology, EarlyView.
Objective We aimed to investigate the associations between Alzheimer's disease (AD)‐related blood biomarkers and changes in brain volumes and cerebrovascular burden in community‐dwelling older adults. Methods We included 361 dementia‐free participants with a Mini‐Mental State Examination (MMSE) score ≥ 27 and without prior cerebrovascular events from a
Martina Valletta   +11 more
wiley   +1 more source

''Wist U ervan?''

open access: yes, 2007
De vuurwerkramp in Enschede, de ingestorte grachttrap in Utrecht, de moord op Theo van Gogh, de aanslagen van 11 september, de Bijlmerramp, de verspreiding van de SARS-pandemie, de Bijlmerramp ... Welke ramp er ook geschiedt, welke fouten er ook worden gemaakt, steevast wordt de vraag gesteld: waren de betrokken autoriteiten op de hoogte en zo ja, had ...
openaire   +1 more source

'Good' platform-political reasons for 'bad' platform data. Zur sozio-technischen Geschichte der Plattformaktivitäten 'Fav', 'Retweet' und 'Like'

open access: yes, 2014
In this article, we explore the relation between platform activities and their usage practices. Taking departure from predefined activities offered by social media platforms, this paper inquires into what may happen if platform features cater to opposing user practices.
Paßmann, Johannes, Gerlitz, Carolin
openaire   +1 more source

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