Results 151 to 160 of about 174,340 (311)

Targeting MGAT4A‐Mediated N‐Glycosylation as a Therapeutic Strategy to Inhibit Glioblastoma Stem Cell Invasion

Exploration, EarlyView.
ABSTRACT Glioblastoma (GBM) is the most aggressive type of primary brain tumor, and its invasive properties contribute significantly to incomplete surgical resection and tumor recurrence. Despite extensive clinical efforts to mitigate GBM invasion, targeted therapies against GBM stem cells (GSCs), which drive invasion, remain incompletely understood ...
Rui Niu, Meichen Liu, Qingshan Yang, Jinlong Yin   +3 more
wiley   +1 more source

Peach Kernel Oil Modulates Lipid Metabolism Disorder in ApoEa CRISPR/Cas9 Gene‐Disrupted Zebrafish

Food Frontiers, EarlyView.
In this study, we used CRISPR/Cas9 gene editing technology to establish a lipid metabolism disorder model of ApoEa mutant zebrafish. We applied peach kernel oil to this model and studied the mechanism of peach kernel oil regulating lipid disorder in combination with transcriptomics.
Lei Xia, Yuemi Mo, Yuntian Duan, Hu Liang, Yulu Li, Wanruo Wan, Minghuang Luo, Qianhua Li, Xueni Wang, Qing Chen, Zhengcai Du, Xiaotao Hou, Fan Zhang, Jiagang Deng, Erwei Hao   +14 more
wiley   +1 more source

Apolipoprotein E Gene ϵ4 Allele is Associated with Atherosclerosis in Multiple Vascular Beds

International Journal of General Medicine
Youni Lin, Min Yang, Qifeng Liu, Yufu Cai, Zhouhua Zhang, Chongfei Xu, Ming Luo Center for Cardiovascular Diseases, Meizhou People’s Hospital, Meizhou, People’s Republic of ChinaCorrespondence: Youni Lin, Center for Cardiovascular Diseases, Meizhou ...
Lin Y, Yang M, Liu Q, Cai Y, Zhang Z, Xu C, Luo M   +6 more
doaj  

Apolipoprotein E knockout attenuates vascular graft fibrosis by reducing profibrotic macrophage formation through low-density lipoprotein receptor related protein 1. [PDF]

Bioact Mater
Fu J, Zhao M, Zhao J, Wu S, Wu J, Hong X, Huang H, Fu G, Xu S.   +8 more
europepmc   +1 more source

APOE4 and cognition in intracranial atherosclerosis: beyond Alzheimer's pathology. [PDF]

Alzheimers Dement
Cheng A, Zou Y, Liu L, Wang H, Ai Z, Wu S, Si Q, Liu Y, Zhou H, Guo H, Yu Q, Wang Z, Li M, Liu C, Xu W.   +14 more
europepmc   +1 more source

'Struggle, not destiny': Introduction to Pierre Raymond, 'Althusser's materialism'

, 2015
On the occasion of the publication of the translation of Pierre Raymond's text on Althusser's materialism, we attempt an introduction to his theoretical trajectory. We begin with his conception of the conflict between materialism and idealism in Le passage au matérialisme in 1973 and his thinking on the question of the history of sciences in ...
openaire   +1 more source

Διοικητική μεταρρύθμιση ''Το σύστημα κινητικότητας των δημοσίων υπαλλήλων''

, 2019
The first part of the paper attempts to analyze the status of civil servants post-war and after the rehabilitation of the Republic, through the only tool that the Government had until that time and which was the Civil Service Code and as it was in force until the crisis period.
openaire   +1 more source

Neutralizing hepatic apolipoprotein E enhances aged bone fracture healing. [PDF]

Bone Res
Huang M, Balu AR, Molitoris KH, Bareja A, Baht GS.   +4 more
europepmc   +1 more source

Erythrokeratoderma ''en cocardes'' [PDF]

, 2020
openaire   +1 more source

Molecular imprinting for neurology: Materials, applications, and limitations

Ibrain, EarlyView.
Molecularly imprinted materials: diagnostic, therapeutic and research applications in neurology. Molecularly imprinted materials offer high specificity and affinity for target molecules in neurological applications. This review highlights their synthesis, characterisation, and use in diagnostics, research and therapeutics.
Xiaohan Ma, Yingqi Ma, Claudia Marino, Alessandro Poma   +3 more
wiley   +1 more source