Results 161 to 170 of about 174,900 (290)

Effects of Changes in Metabolic Syndrome Status on Cognitive Function: A 10‐Year Study in a Middle‐Aged Population

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The long‐term cumulative impact of metabolic syndrome (MS) on cognitive decline remains uncertain. This study investigated how changes in MS status over 10 years relate to cognition and whether sex modifies this relationship. A total of 766 participants (mean baseline age: 54 years) from the Kaohsiung Atherosclerosis Longitudinal Study were ...
Kelly Lim   +6 more
wiley   +1 more source

An automated plasma-based proteotyping immunoassay for APOE ε4 zygosity classification in Alzheimer's disease. [PDF]

open access: yesAlzheimers Dement
Levin S   +15 more
europepmc   +1 more source

Proteomics‐Based Identification of the Pyroptosis‐Related Biomarker PCSK9 and Its Association With the Pathogenesis of Rheumatoid Arthritis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Rheumatoid arthritis (RA) is a common autoimmune disease, and early diagnosis is critical for effective treatment. This study aims to identify potential biomarkers related to pyroptosis through serum proteomics analysis, offering new insights for the early diagnosis of RA.
Lei Wang   +10 more
wiley   +1 more source

Is there a role for apolipoprotein E in perinatal brain injury? [PDF]

open access: yesMol Cell Pediatr
Abraham-Pol S, Mayatepek E, Dzietko M.
europepmc   +1 more source

Chronic, Environmentally Relevant PM2.5 Exposure Exacerbates Metabolic Dysfunction‐Associated Steatotic Liver Disease and Early‐Stage Renal Dysfunction in a Rodent Model

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT While epidemiological studies link fine particulate matter (PM2.5) exposure to metabolic dysfunction‐associated steatotic liver disease (MASLD) and renal dysfunction, a translational gap exists, as most animal models utilize acute, high‐dose exposures that poorly reflect chronic, moderate‐level human scenarios.
Yi‐Siao Chen   +11 more
wiley   +1 more source

Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu   +4 more
wiley   +1 more source

ACE I/D polymorphism in Alzheimer’s disease

open access: yesOpen Life Sciences, 2008
Trebunova Marianna   +3 more
doaj   +1 more source

Age at natural menopause, reproductive lifespan and Alzheimer's disease in females: is APOE ε4 the missing link? [PDF]

open access: yesFront Genet
Bruno F   +15 more
europepmc   +1 more source

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