Results 111 to 120 of about 95,854 (268)

Causal correlations between inflammatory proteins and heart failure: A two‐sample Mendelian randomization analysis

ESC Heart Failure, Volume 12, Issue 2, Page 1374-1385, April 2025.
Abstract Aims Inflammation plays a critical role in both the development and progression of heart failure (HF), which is a leading cause of morbidity and mortality worldwide. However, the causality between specific inflammation‐related proteins and HF risk remains unclear.
Xian‐Guan Zhu, Gui‐Qin Liu, Ya‐Ping Peng, Li‐Ling Zhang, Xian‐Jin Wang, Liang‐Chuan Chen, Yuan‐Xi Zheng, Xue‐Jun Xiang, Rui Qiao, Xian‐He Lin   +9 more
wiley   +1 more source

Exercise‐specific plasma proteomic signatures in racehorses: Candidates for training adaptation and peak load monitoring

Equine Veterinary Journal, EarlyView.
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka, Bianka Świderska, Ewa Sitkiewicz, Izabela Dąbrowska, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Differential course of HIV-1 infection and apolipoprotein E polymorphism

Open Medicine, 2007
Corder Elizabeth, Galeazzi Luciano, Franceschi Claudio, Cossarizza Andrea, Paganelli Roberto, Pinti Marcello, Mussini Cristina, Borghi Vanni, Pinter Elena, Cristofaro Rita, Galeazzi Roberta, Perini Marino, Aiuti Fernando, Giunta Sergio   +13 more
doaj   +1 more source

'Career preference', 'transients' and 'converts': A study of social workers' retention in child protection and welfare

, 2011
Both domestically and internationally, retaining social workers in statutory child protection and welfare work has been identified as a problem. However, this issue appears to receive only modest attention from researchers. This paper reports on the findings of a study that examined the retention of ‘front line’ child protection and welfare social ...
openaire   +1 more source

What's in a name? The value of 'Entrepreneurs' compared to 'Self-Employed'...but what about 'Freelancing' or 'IPro'?

This paper is concerned with those individuals who do not fit easily or comfortably into traditional notions of employment. Variously described as 'self-employed', 'sole traders', 'own account workers,' 'freelancers,' 'independent contractors' - or more accurately, as independent professionals (IPros ...
openaire   +1 more source

Synthesis of the WXYZA'B'C'D'E'F' Ring of Maitotoxin

Journal of Synthetic Organic Chemistry, Japan, 2023
Umeno, Keitaro, Oishi, Tohru
openaire   +1 more source

Gut microbiota‐mediated immune and metabolic dysregulation in coronary artery disease progression and prognosis

iMeta, EarlyView.
The gut microbiota has emerged as a metabolically active endocrine‐like organ with a crucial role in coronary artery disease (CAD), yet its contribution to adverse clinical outcomes remains incompletely understood. In this prospective cohort of 319 participants, we integrated metagenomic and metabolomic profiling with longitudinal follow‐up over a ...
Honghong Liu, Siqin Feng, Lifeng Liang, Muyun Tang, Yifei Wang, Yiyang Wang, Zhiyu Zhang, Haiping Xing, Chenhong Zhang, Ran Tian, Shuyang Zhang   +10 more
wiley   +1 more source

Non‐Nutritive Artificial Sweeteners Aspartame and Acesulfame‐K Ameliorate Metabolic Dysfunction‐Associated Steatotic Liver Disease in Male Ldlr−/− Mice

iNew Medicine, EarlyView.
ABSTRACT Aspartame and acesulfame‐K are commonly used non‐nutritive artificial sweeteners, but their impacts on cardiovascular disease and metabolic dysfunction‐associated fatty liver disease (MASLD) are unclear. In this study, we evaluated the impacts of aspartame and acesulfame‐K on MASLD and atherosclerosis in male Ldlr−/− mice fed an AMLN diet ...
Jingjing Xu, Xiaohua Jiang, Jianping Weng, Suowen Xu   +3 more
wiley   +1 more source

Haplotype-resolved DNA methylation at the <i>APOE</i> locus identifies allele-specific epigenetic signatures relevant to Alzheimer's disease risk. [PDF]

NPJ Dement
Genner RM, Meredith M, Daida K, Moller A, Weller C, Ayuketah A, Jerez PA, Akeson S, Malik L, Baker B, Kouam C, Paquette K, Catching A, Bromberek S, Hu F, Reed X, Marenco S, Auluck P, Mandal A, Paten B, Gibbs JR, Jain M, Cookson MR, Singleton AB, Nalls M, Blauwendraat C, Billingsley KJ.   +26 more
europepmc   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source