Results 141 to 150 of about 92,484 (303)

Apolipoprotein C-III [PDF]

, 2018
K. J. Lackner, D. Peetz
openaire   +4 more sources

A review of the role of apolipoprotein C-II in lipoprotein metabolism and cardiovascular disease

, 2012
The focus of this review is on the role of apolipoprotein C-II (apoC-II) in lipoprotein metabolism and the potential effects on the risk of cardiovascular disease (CVD). We searched PubMed/Scopus for articles regarding apoC-II and its role in lipoprotein
Elisaf, M. S., Tsimihodimos, V., Kei, A. A., Filippatos, T. D.   +3 more
core  

A dual apolipoprotein C-II mimetic-apolipoprotein C-III antagonist peptide lowers plasma triglycerides. [PDF]

Sci Transl Med, 2020
Wolska A, Lo L, Sviridov DO, Pourmousa M, Pryor M, Ghosh SS, Kakkar R, Davidson M, Wilson S, Pastor RW, Goldberg IJ, Basu D, Drake SK, Cougnoux A, Wu MJ, Neher SB, Freeman LA, Tang J, Amar M, Devalaraja M, Remaley AT.   +20 more
europepmc   +1 more source

Delivery of human apolipoprotein (apo) E to liver by an [E1(-), E3(-), polymerase(-), pTP(-)] adenovirus vector containing a liver-specific promoter inhibits atherogenesis in immunocompetent apoE-deficient mice

, 2006
Recombinant adenovirus (rAd)-mediated apoE gene transfer to the liver of apoE(-/-) mice is anti-atherogenic. However, first generation rAd vectors were associated with immune clearance of transduced hepatocytes, while an improved [E1(-), E3(-) polymerase(
Amalfitano, A, Owen, JS, Dickson, G, Graham, IR, Harris, JD   +4 more
core  

Localization of apolipoprotein A-I and apolipoprotein A-II in human atherosclerotic arteries.

Archives of pathology & laboratory medicine, 1989
Apolipoprotein A-I and apolipoprotein A-II, the two major protein components of the high-density lipoproteins, were visualized in human arteries using an immunofluorescence technique. Apolipoprotein A-I and apolipoprotein A-II were codeposited into the intima and upper media of normal arteries of atherosclerotic patients.
P, Bedossa, T, Poynard, A, Abella, F, Paraf, G, Lemaigre, E, Martin   +5 more
openaire   +1 more source

Uptake mechanism of ApoE-modified nanoparticles on brain capillary endothelial cells as a blood-brain barrier model

, 2012
Background: The blood-brain barrier (BBB) represents an insurmountable obstacle for most drugs thus obstructing an effective treatment of many brain diseases.
Tikva Vogel, Zensi, Anja, von Briesen Hagen, Kreuter Jörg, Worek Franz, Tschickardt, Sabrina E., Sascha L Wien, Jörg Kreuter, Wien Sascha L., Vogel Tikva, Sabrina E Tschickardt, Wladislaw Maier, Vogel, Tikva, Sylvia Wagner, Claus U Pietrzik, Maier Wladislaw, Zensi Anja, Wien, Sascha L., Maier, Wladislaw, Tschickardt Sabrina E., Wagner, Sylvia, Pietrzik Claus U., Anja Zensi, Kreuter, Jörg, Worek, Franz, Hagen von Briesen, Pietrzik, Claus Ulrich, Briesen, Hagen von, Wagner Sylvia, Franz Worek   +29 more
core   +1 more source

The activation of lipoprotein lipase by apolipoprotein C-II

Abnormalities in blood lipid levels are common in our society. Treatment of these conditions adds a heavy burden to national health-care costs. Lipoprotein lipase is a plasma enzyme that plays a central role in maintaining safe blood lipid levels.

core  

Proposed folding pattern for apolipoprotein A-II based on a structural analogy with uteroglobin.

, 1988
The tertiary structure observed in the crystalline state for uteroglobin, a small steroid binding protein, is used as a template to build an approximated model for apolipoprotein A-II.
De Coen, Jean-Louis, Delcroix, Claude, Lontie, Jean-Francois, Malmendier, Claude, Deboeck, M.   +4 more
core  

Apolipoprotein A-II Production Rate Is a Major Factor Regulating the Distribution of Apolipoprotein A-I Among HDL Subclasses LpA-I and LpA-I:A-II in Normolipidemic Humans

, 1995
HDLs are heterogeneous in their apolipoprotein composition. Apolipoprotein (apo) A-I and apoA-II are the major proteins found in HDL and form the two major HDL subclasses: those that contain only apoA-I (LpA-I) and those that contain both apoA-I and apoA-
Katsunori Ikewaki, Daniel J. Rader, Loren A. Zech, H. Bryan Brewer, Marie Kindt   +4 more
core   +1 more source

Rethinking apolipoprotein A-II in lipid metabolism [PDF]

The American Journal of Clinical Nutrition, 2018
openaire   +2 more sources