Results 1 to 10 of about 125,098 (310)

On the Aggregation of Apolipoprotein A-I. [PDF]

Int J Mol Sci, 2022
In vivo, apolipoprotein A-I (ApoA-I) is commonly found together with lipids in so-called lipoprotein particles. The protein has also been associated with several diseases—such as atherosclerosis and amyloidosis—where insoluble aggregates containing ApoA-I are deposited in various organs or arteries.
Frankel R, Sparr E, Linse S.
europepmc   +3 more sources

Apolipoprotein A-I mimetics [PDF]

Current Opinion in Lipidology, 2014
To summarize recent publications in the field of apolipoprotein mimetics.Apolipoprotein mimetic peptides continue to show efficacy in a number of animal models of disease and demonstrate properties that make them attractive as potential therapeutic agents. A number of new apolipoprotein mimetics have been described recently.
Reddy, Srinivasa T, Navab, Mohamad, Anantharamaiah, Gattadahalli M, Fogelman, Alan M   +3 more
openaire   +6 more sources

Apolipoprotein A-I and A-I mimetic peptides: a role in atherosclerosis

Journal of Inflammation Research, 2011
Godfrey S Getz, Catherine A ReardonThe University of Chicago, Department of Pathology, Chicago, IL, USAAbstract: Cardiovascular disease remains a major cause of morbidity and mortality in the westernized world.
Getz GS, Reardon CA
doaj   +1 more source

Impact of Glucose Metabolism Status on the Association between Apolipoprotein A-I and Ischemic Risk in Patients with Coronary Artery Disease: A Large-Sample Cohort Study [PDF]

Endocrinology and Metabolism
Background Apolipoprotein A-I (ApoA-I) is a key cardioprotective lipoprotein. Nevertheless, it remains unclear how ApoA-I relates to ischemic risk across glucose metabolism statuses in patients with coronary artery disease (CAD).
Kailun Yan, Jiawen Li, Kexin Zhang, Menglu Liu, Pei Zhu, Xiaofang Tang, Deshan Yuan, Yuejin Yang, Runlin Gao, Jinqing Yuan, Xueyan Zhao   +10 more
doaj   +2 more sources

Autoantibodies to apolipoprotein A-I in hepatitis C virus infection: a role in disease progression? [PDF]

Front Immunol
Background: Chronic HCV (CHC) infection is associated with autoimmunity. IgG autoantibodies to apolipoprotein A-I (AAA-I) predict all-cause mortality. We evaluated AAA-I in CHC patients and in those who were not viraemic, either because of spontaneous ...
Bridge SH, Pagano S, Lodge JK, Shawa IT, Marin-Crespo P, Cramp ME, Sheridan DA, Taylor-Robinson SD, Vuilleumier N, Neely RDG, Bassendine MF.   +10 more
europepmc   +2 more sources

The Level of Apolipoprotein A-I Is Associated with a Prognosis in Patients with Chronic Heart Failure Especially in HFmrEF and HFpEF: A Retrospective Cohort Study. [PDF]

Int J Gen Med
XueChun He,1,* FaPeng Li,2,* Jian Zhang,1 ZhiYing Wen,1 YanXiao Li,3 WeiTong Gao,1 HongXia Chen,1 YangGuang Yu,1 YingYing Zheng,1 Xiang Xie1 1Department of Cardiology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi ...
He X, Li F, Zhang J, Wen Z, Li Y, Gao W, Chen H, Yu Y, Zheng Y, Xie X.   +9 more
europepmc   +2 more sources

Apolipoprotein A-I and Cancer [PDF]

Frontiers in Pharmacology, 2015
High-density lipoprotein (HDL) and apolipoprotein A-I (apoA-I), the predominant protein in plasma HDL, have long been the focus of intense studies in the field of atherosclerosis and cardiovascular disease. ApoA-I, in large part, is responsible for HDL assembly and its main atheroprotective function, that of shuttling excess cholesterol from peripheral
Zamanian-Daryoush, Maryam, DiDonato, Joseph A.   +1 more
openaire   +2 more sources

Apolipoprotein A-I: Potential Protection Against Intestinal Injury Induced by Dietary Lipid. [PDF]

J Inflamm Res
Jue-Xin Wang,1– 3,* Shi-Jia Yu,4,* Gang Huang,1,2 Yan-Bo Yu,1,2 Yan-Qing Li1,2 1Department of Gastroenterology, Qilu Hospital of Shandong University, Jinan, Shandong Province, 250012, People’s Republic of China; 2Laboratory of Translational ...
Wang JX, Yu SJ, Huang G, Yu YB, Li YQ.
europepmc   +2 more sources

Apolipoprotein A‐I induced amyloidosis [PDF]

FEBS Letters, 1998
Amyloidosis is characterized by extracellular deposits of protein fibrils with a high content of β‐sheets in secondary structure. The protein forms together with proteoglycans amyloid fibrils causing organ damage and serious morbidity. Intact apolipoprotein A‐I (apoA‐I) is an important protein in lipid metabolism regulating the synthesis and catabolism
Genschel, Janine, Haas, Regina, Pröpsting, Marcus J, Schmidt, Hartmut H.-J   +3 more
openaire   +2 more sources

The apolipoprotein B and apolipoprotein A-I Ratio serves as a strong prognostic factor for the overall survival of patients with colorectal cancer

Frontiers in Oncology, 2023
BackgroundThe lipid metabolism status of patients with colorectal cancer (CRC) has not been understood comprehensively. The present study investigated the characteristics of lipid metabolism parameters in CRC patients with or without metastases and ...
Yangxun Pan, Yangxun Pan, Yangxun Pan, Zhiwei Ye, Zhiwei Ye, Yihong Ling, Yihong Ling, Lingheng Kong, Lingheng Kong, Chenwei Wang, Chenwei Wang, Gong Chen, Gong Chen, Desen Wan, Desen Wan, Minshan Chen, Minshan Chen, Dandan Hu, Dandan Hu   +18 more
doaj   +1 more source