Results 31 to 40 of about 125,098 (310)

Volumetric determination of apolipoprotein stoichiometry of circulating HDL subspecies1[S]

Journal of Lipid Research, 2013
Although HDL is inversely correlated with coronary heart disease, elevated HDL-cholesterol is not always protective. Additionally, HDL has biological functions that transcend any antiatherogenic role: shotgun proteomics show that HDL particles contain 84
Jere P. Segrest, Marian C. Cheung, Martin K. Jones   +2 more
doaj   +1 more source

Apolipoprotein A-I Deficiency [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 1995
Abstract Familial HDL deficiencies are associated with variable susceptibility to premature coronary heart disease, but the mechanism underlying this association remains poorly understood. Three homozygotes with isolated complete apo A-I deficiency caused by an autosomal codominant apo A-I Q[−2]X mutation and one heterozygote ...
D S, Ng, C, Vezina, T S, Wolever, A, Kuksis, R A, Hegele, P W, Connelly   +5 more
openaire   +2 more sources

Serum apolipoproteins in relation to intakes of fish in population of Arkhangelsk County

Nutrition & Metabolism, 2012
Background Diets rich in omega-3 fatty acids and low in saturated fat were found beneficially associated with blood lipids and cardio-vascular health. Lean reindeer meet and local cold water white-fish species high in omega-3 are among the main sources ...
Petrenya Natalia, Brustad Magritt, Cooper Marie, Dobrodeeva Liliya, Bichkaeva Fatima, Lutfalieva Gulnara, Odland Jon   +6 more
doaj   +1 more source

Genetic variants in Apolipoprotein AV alter triglyceride concentrations in pregnancy. [PDF]

, 2003
BACKGROUND: Triglyceride concentrations are raised in pregnancy and are considered a key fetal fuel. Several gene variants are known to alter triglyceride concentrations, including those in the Apolipoprotein E (ApoE), Lipoprotein Lipase (LPL), and most ...
Andrew T Hattersley, Beatrice Knight, Kirsten J Ward, Ward Kirsten J, Knight Beatrice, Hattersley, Andrew T, Ward, Kirsten J, Maurice B Salzmann, Timothy M Frayling, Frayling, Timothy M, Beverley Shields, Shields, Beverley, Salzmann Maurice B, Hattersley Andrew T, Shields Beverley, Frayling Timothy M, Knight, Beatrice, Salzmann, Maurice B   +17 more
core   +1 more source

ApoA-I cleaved by transthyretin has reduced ability to promote cholesterol efflux and increased amyloidogenicity

Journal of Lipid Research, 2007
A fraction of plasma transthyretin (TTR) circulates in HDL through binding to apolipoprotein A-I (apoA-I). Moreover, TTR is able to cleave the C terminus of lipid-free apoA-I.
Márcia Almeida Liz, Cláudio M. Gomes, Maria João Saraiva, Mónica Mendes Sousa   +3 more
doaj   +1 more source

Evaluation of Lipid Profile, Apo B/ Apo A Ratio and Lpa and its Relationship with Cognitive Disorders in the Older Adults: Birjand Longitudinal Aging Study

Archives of Advances in Biosciences, 2023
Introduction: Accurate and timely diagnosis of mild cognitive disorders is essential to prevent their progression to dementia. This study aimed to determine the relationship among the serum levels of lipid markers of cognitive disorders in older adults ...
Sara Hamdamian, Asghar Zarban , Mitra Moodi, Farshad Sharifi, rasoul raesi, Mohammad Dehghani Firoozabadi   +5 more
doaj   +1 more source

The age-related paraoxonase 1 response is altered by long-term caloric restriction in male and female rats

Journal of Lipid Research, 2006
Caloric restriction (CR) has been shown to attenuate age-related oxidative damage and to improve major atherosclerotic risk factors. Paraoxonase 1 (PON1), an enzyme specifically associated with HDL containing apolipoproteins A-I and J, has been reported ...
Elena Thomàs-Moyà, Magdalena Gianotti, Ana M. Proenza, Isabel Lladó   +3 more
doaj   +1 more source

Effect of urotensin II on apolipoprotein B 100 and apolipoprotein A-I expression in HepG2 cell line

Advanced Biomedical Research, 2014
Background: Increased apolipoprotein B100 (apo B) and decreased apolipoprotein A-I (apo A-I) production are important risk factors in atherosclerosis.
Abbas Mohammadi, Ahmad Gholamhoseinian Najar, Amirhosein Khoshi   +2 more
doaj   +1 more source

Characterization of four lipoprotein classes in human cerebrospinal fluid

Journal of Lipid Research, 2001
Lipoprotein metabolism in brain has not yet been fully elucidated, although there are a few reports concerning lipids in the brain and lipoproteins and apolipoproteins in the cerebrospinal fluid (CSF).
Stefanie Koch, Nicolette Donarski, Kathrin Goetze, Miriam Kreckel, Hans-Joerg Stuerenburg, Carsten Buhmann, Ulrike Beisiegel   +6 more
doaj   +1 more source

Endothelial lipase is less effective at influencing HDL metabolism in vivo in mice expressing apoA-II

Journal of Lipid Research, 2006
Endothelial lipase (EL) plays an important physiological role in modulating HDL metabolism. Data suggest that plasma contains an inhibitor of EL, and previous studies have suggested that apolipoprotein A-II (apoA-II) inhibits the activity of several ...
Uli C. Broedl, Weijun Jin, Ilia V. Fuki, John S. Millar, Daniel J. Rader   +4 more
doaj   +1 more source