Results 1 to 10 of about 698,194 (130)

Apolipoprotein A-I modulates HDL particle size in the absence of apolipoprotein A-II [PDF]

Journal of Lipid Research, 2021
Human high-density lipoproteins (HDLs) are a complex mixture of structurally related nanoparticles that perform distinct physiological functions. We previously showed that human HDL containing apolipoprotein A-I (APOA1) but not apolipoprotein A-II (APOA2)
John T. Melchior, Scott E. Street, Tomas Vaisar, Rachel Hart, Jay Jerome, Zsuzsanna Kuklenyik, Noemie Clouet-Foraison, Carissa Thornock, Shimpi Bedi, Amy S. Shah, Jere P. Segrest, Jay W. Heinecke, W. Sean Davidson   +12 more
doaj   +4 more sources

Apolipoprotein A-II, a Player in Multiple Processes and Diseases

Biomedicines, 2022
Apolipoprotein A-II (apoA-II) is the second most abundant apolipoprotein in high-density lipoprotein (HDL) particles, playing an important role in lipid metabolism.
Gabriela Florea, Irina Florina Tudorache, Elena Valeria Fuior, Radu Ionita, Madalina Dumitrescu, Ioana Madalina Fenyo, Violeta Georgeta Bivol, Anca Violeta Gafencu   +7 more
doaj   +2 more sources

Radioimmunoassay of Apolipoprotein A‐II [PDF]

Arteriosclerosis: An Official Journal of the American Heart Association, Inc., 1982
A double antibody radioimmunoassay was developed for apolipoprotein A-II (apo A-II), one of the two major apoproteins of human high density lipoproteins (HDL). Apo A-II contains two identical polypeptide chains linked by a disulfide bond. A specific antiserum was raised in sheep. Tracer apo A-II was radiolabeled with 125I by the Bolton-Hunter technique.
T. Musliner, P. A. Garner, L. Henderson, P. Herbert   +3 more
semanticscholar   +3 more sources

Influence of apolipoprotein A-I and apolipoprotein A-II availability on nascent HDL heterogeneity [PDF]

Journal of Lipid Research, 2013
It is important to understand HDL heterogeneity because various subspecies possess different functionalities. To understand the origins of HDL heterogeneity arising from the existence of particles containing only apoA-I (LpA-I) and particles containing ...
Eric T. Alexander, Michael C. Phillips
doaj   +3 more sources

Protein heterogeneity of lipoprotein particles containing apolipoprotein A-I without apolipoprotein A-II and apolipoprotein A-I with apolipoprotein A-II isolated from human plasma.

Journal of Lipid Research, 1988
The protein heterogeneity of fractions isolated by immunoaffinity chromatography on anti-apolipoprotein A-I and anti-apolipoprotein A-II affinity columns was analyzed by high resolution two-dimensional gel electrophoresis.
R W James, D Hochstrasser, J D Tissot, M Funk, R Appel, F Barja, C Pellegrini, A F Muller, D Pometta   +8 more
doaj   +3 more sources

Low apolipoprotein A-II levels causally contribute to increased mortality in septic shock

Journal of Intensive Care
Background Lipoproteins and their component apolipoproteins play an important role in sepsis. However, little is known with regard to the association and causal contribution of these proteins to mortality in patients of different ancestries following ...
Nozomi Takahashi, Kyle R. Campbell, Tadanaga Shimada, Taka-aki Nakada, James A. Russell, Keith R. Walley   +5 more
doaj   +2 more sources

Human apolipoprotein A-I and A-II metabolism

Journal of Lipid Research, 1982
The kinetics of the major apolipoproteins (apo) of plasma high density lipoproteins (HDL), apoA-I and apoA-II, were examined in a total of 44 individual tracer studies in 22 normal male and female subjects.
E J Schaefer, L A Zech, L L Jenkins, T J Bronzert, E A Rubalcaba, F T Lindgren, R L Aamodt, H B Brewer, Jr   +7 more
doaj   +3 more sources

Immunonephelometry of apolipoprotein A-II in plasma.

Clinical Chemistry, 1984
Abstract A quantitative assay based on endpoint immunonephelometry was developed for human apolipoprotein A-II (apoA-II) in plasma or serum. Dilution of plasma samples with a 0.1 mol/L solution of sodium cholate enhanced the quantification. We used either purified apoA-II as the primary standard or plasma as a secondary standard. Results
M. Rosseneu, N. Vinaimont, T. Musliner, D. Bernier, P. Herbert, F. Belpaire   +5 more
semanticscholar   +3 more sources

Turbidimetric Assay of Apolipoprotein A-II [PDF]

Clinical Chemistry and Laboratory Medicine, 1985
A turbidimetric assay for the quantification of apolipoprotein A-II in serum is described. Its adaptation for the Cobas Bio Analyser (Hoffmann La Roche) is reported. Regression analysis of apolipoprotein A-II values measured by turbidimetry revealed a good measure of agreement with the data obtained by radial immunodiffusion (RID) (r = 0.90, y = 0.97x +
Schriewer, H., Emke, F., Assmann, G.
openaire   +3 more sources

Immunonephelometric Determination of the Apolipoprotein A-II [PDF]

Clinical Chemistry and Laboratory Medicine, 1989
A fully mechanized immunonephelometric method is described for the rapid and specific determination of apolipoprotein A-II in serum. The method utilizes commercially available sheep antiserum against human apolipoprotein A-II. Nephelometry was performed with the Behring Nephelometer Analyzer (BNA). A single determination can be performed in 12 minutes,
Hafner, G., Luley, C., Prellwitz, W.
openaire   +2 more sources