Results 21 to 30 of about 97,019 (266)
Biochemistry and Biophysics Reports, 2020 Background: Apolipoprotein A-I (apoA-I) protects against atherosclerosis and participates in the removal of excess cellular cholesterol from peripheral organs. Several naturally occurring apoA-I mutations are associated with familial systemic amyloidosis,
Farah Ma'arfi +5 more
doaj +1 more source
Journal of Lipid Research, 2005 The exchangeable apolipoproteins present in small, dense LDL (sdLDL) and large, buoyant LDL subclasses were evaluated with a quantitative proteomic approach in patients with the metabolic syndrome and with type 2 diabetes, both with subclinical ...
Pia Davidsson +6 more
doaj +1 more source
Apolipoprotein A‐I: the dual face of a protein [PDF]
FEBS Letters, 2016 Conformational plasticity and flexibility are key structural features of ApoAI in lipid metabolism. Amyloidogenic single point mutations, associated with incurable familial amyloidosis with fibril deposition in peripheral organs, may have a dramatic impact on the structural and functional features of ApoAI.
ARCIELLO, ANGELA +2 more
openaire +3 more sources
Serum apolipoproteins in relation to intakes of fish in population of Arkhangelsk County
Nutrition & Metabolism, 2012 Background Diets rich in omega-3 fatty acids and low in saturated fat were found beneficially associated with blood lipids and cardio-vascular health. Lean reindeer meet and local cold water white-fish species high in omega-3 are among the main sources ...
Petrenya Natalia +6 more
doaj +1 more source
Importance of Apolipoprotein A-I in Multiple Sclerosis [PDF]
Frontiers in Pharmacology, 2015 Jean-Martin Charcot has first described multiple sclerosis (MS) as a disease of the central nervous system (CNS) over a century ago. MS remains incurable today, and treatment options are limited to disease modifying drugs. Over the years, significant advances in understanding disease pathology have been made in autoimmune and neurodegenerative ...
Lidia A Gardner +4 more
openaire +5 more sources
Journal of Lipid Research, 2007 A fraction of plasma transthyretin (TTR) circulates in HDL through binding to apolipoprotein A-I (apoA-I). Moreover, TTR is able to cleave the C terminus of lipid-free apoA-I.
Márcia Almeida Liz +3 more
doaj +1 more source
Apolipoprotein A-I Deficiency [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 1995 Abstract Familial HDL deficiencies are associated with variable susceptibility to premature coronary heart disease, but the mechanism underlying this association remains poorly understood. Three homozygotes with isolated complete apo A-I deficiency caused by an autosomal codominant apo A-I Q[−2]X mutation and one heterozygote ...
D S, Ng +5 more
openaire +2 more sources
Archives of Advances in Biosciences, 2023 Introduction: Accurate and timely diagnosis of mild cognitive disorders is essential to prevent their progression to dementia. This study aimed to determine the relationship among the serum levels of lipid markers of cognitive disorders in older adults ...
Sara Hamdamian +5 more
doaj +1 more source
Journal of Lipid Research, 2006 Caloric restriction (CR) has been shown to attenuate age-related oxidative damage and to improve major atherosclerotic risk factors. Paraoxonase 1 (PON1), an enzyme specifically associated with HDL containing apolipoproteins A-I and J, has been reported ...
Elena Thomàs-Moyà +3 more
doaj +1 more source
Effect of urotensin II on apolipoprotein B 100 and apolipoprotein A-I expression in HepG2 cell line
Advanced Biomedical Research, 2014 Background: Increased apolipoprotein B100 (apo B) and decreased apolipoprotein A-I (apo A-I) production are important risk factors in atherosclerosis.
Abbas Mohammadi +2 more
doaj +1 more source