Results 111 to 120 of about 280,160 (254)
Apolipoprotein A1 (apoA1) is the major protein component of high-density lipoprotein (HDL) and has well documented anti-inflammatory properties. To better understand the cellular and molecular basis of the anti-inflammatory actions of apoA1, we explored ...
A. Iqbal +15 more
semanticscholar +1 more source
Gene structure of human apolipoprotein A1.
Apolipoprotein A1 is the major polypeptide of the human plasma high density lipoprotein (HDL). The structure and function of the apo A1 gene are of interest because of the inverse correlation shown between HDL levels and coronary heart disease. We have determined the nucleotide sequence of the apo A1 gene previously isolated.
C C, Shoulders +3 more
openaire +1 more source
ABSTRACT Purpose Metabolic syndrome (MetS) is a common complication in survivors of childhood acute lymphoblastic and myeloid leukemia (AL), and a major risk factor for premature cardiovascular disease, type‐2‐diabetes, and metabolic dysfunction‐associated steatotic liver disease (MASLD).
Visentin Sandrine +10 more
wiley +1 more source
A high‐throughput in vivo mRNA LNP screening platform is developed and employed to screen a large library of 122 mRNA LNPs in vivo for delivery to immune, stromal, and parenchymal cells, identifying promising LNP candidates. A novel small particle flow cytometry‐based protein adsorption analysis method is utilized to interrogate protein corona ...
Alex G. Hamilton +17 more
wiley +1 more source
Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du +5 more
wiley +1 more source
Serum apolipoprotein A1: a predictor and prognostic biomarker in acute ischemic stroke
Background The apolipoprotein A1 level is recognized as a better indicator of cardiovascular disease than other cholesterol measures. Objectives To assess the serum level of ApoA1 in acute stroke patients and correlate it with the degree of vessel ...
Mai A. Eldeeb +5 more
doaj +1 more source
Aim. To study influence of coronary heart disease (CHD) in family history on distribution of polymorphism apolipoprotein A1, В and E genes of the lipidtransport systems and major adverse cardiac events (MACE) in patients of Uzbek nationality with ...
F. M. Bekmetova +5 more
doaj +1 more source
Abstract Emerging evidence highlights the central role of peripheral immune–metabolic regulation in the pathogenesis of Alzheimer's disease and related dementias (ADRD). Among peripheral organs, the spleen has gained increasing attention as a critical immune–metabolic hub linking systemic homeostasis to central neurodegeneration.
Jingsi Yan +7 more
wiley +1 more source
Background Physical activity has long been associated with reduced risk of coronary heart disease (CHD). In this work we evaluated the effect of physical activity on lipid levels, in a sample of cardiovascular disease free people.
Papaioannou Ioanna +8 more
doaj +1 more source
Abstract INTRODUCTION We aimed to define the genetic architecture and regulatory mechanisms of Alzheimer's disease (AD) ‐related plasma biomarkers in an East Asian population. METHODS Genome‐wide association studies (GWAS) of plasma phosphorylated tau at threonine 217 (pTau217), pTau181, neurofilament light chain (NfL), and glial fibrillary acidic ...
Jun Pyo Kim +22 more
wiley +1 more source

