Comparative proteome analysis of the ligamentum flavum of patients with lumbar spinal canal stenosis
JOR SPINE, Volume 5, Issue 4, December 2022., 2022 This study investigated the pathology of thickened ligamentum flavum in patients with lumbar spinal canal stenosis (LSCS) based on protein expression levels using shotgun proteome analysis. The results showed that tissue repair via fibrosis, chondrometaplasia, and amyloid deposits may be important pathologies that occur in the thickened ligamentum ...
Yutaka Yabe +8 more
wiley +1 more source
Sharp two parameter bounds for logarithmic and arithmetic-geometric means [PDF]
arXiv, 2012 For fixed $s\geq 1$ and $t_{1},t_{2}\in(0,1/2)$ we prove that the inequalities $G^{s}(t_{1}a+(1-t_{1})b,t_{1}b+(1-t_{1})a)A^{1-s}(a,b)>AG(a,b)$ and $G^{s}(t_{2}a+(1-t_{2})b,t_{2}b+(1-t_{2})a)A^{1-s}(a,b)>L(a,b)$ hold for all $a,b>0$ with $a\neq b$ if and only if $t_{1}\geq 1/2-\sqrt{2s}/(4s)$ and $t_{2}\geq 1/2-\sqrt{6s}/(6s)$. Here $G(a,b)$, $L(a,b)$,
arxiv
Analysis of the apolipoprotein B gene and messenger ribonucleic acid in abetalipoproteinemia. [PDF]
, 1986 Karl J. Lackner +6 more
openalex +1 more source
Copper in cancer: friend or foe? Metabolism, dysregulation, and therapeutic opportunities
Cancer Communications, EarlyView.Abstract Copper, one of the essential nutrients for the human body, acts as an electron relay in multiple pathways due to its redox properties. Both deficiencies and excesses of copper lead to cellular fragility. Therefore, it can manifest pro‐ and anti‐cancer properties in tumors. Therefore, it is crucial to clarify the copper activity within the cell.
Dan Shan +13 more
wiley +1 more source
Asian Journal of Medical SciencesSir, Dyslipidemia is one of the important risk factors for cardiovascular (CV) diseases. As per the current consensus, we assess lipid-derived risk by looking at traditional lipid parameters.
Avijit Saha
doaj +1 more source
Impact of maternal high fat on neurovascular unit of adult offspring [PDF]
arXivMaternal obesity is associated with increased risk of diabetes, cardiovascular disease and hypertension in adult offspring. Midlife hypercholesterolemia and hypertension are risk factors for Alzheimer's disease, suggesting that the ageing brain may be impacted by early life environment.
arxiv
Genetic evidence from two families that the apolipoprotein B gene is not involved in abetalipoproteinemia. [PDF]
, 1988 Philippa J. Talmud +5 more
openalex +1 more source
Serotonergic modulators in Alzheimer's disease: a hope in the hopeless condition
Chemistry &Biodiversity, Accepted Article.Alzheimer disease (AD) is the main cause of dementia worldwide. AD is a progressive brain neurodegenerative disease due to genetic and environmental factors that induce a progressive accumulation of intracellular hyperphosphorylated tau protein and extracellular amyloid protein (Aβ).
Ali I. Al-Gareeb +5 more
wiley +1 more source
Apolipoprotein B in cardiovascular risk assessment. [PDF]
CMAJ, 2023 Ahmad M, Sniderman AD, Hegele RA.
europepmc +1 more source
Modeling Interconnected Modules in Multivariate Outcomes: Evaluating the Impact of Alcohol Intake on Plasma Metabolomics [PDF]
arXivAlcohol consumption has been shown to influence cardiovascular mechanisms in humans, leading to observable alterations in the plasma metabolomic profile. Regression models are commonly employed to investigate these effects, treating metabolomics features as the outcomes and alcohol intake as the exposure. Given the latent dependence structure among the
arxiv