Results 161 to 170 of about 381,163 (319)

Utility of apolipoprotein measurements in predicting incident type 2 diabetes: A Chinese cohort study

Journal of the Formosan Medical Association, 2020
Background/purpose: There is conflicting data regarding the utility of measuring apolipoproteins in addition to traditional lipid measures in risk assessment of cardiometabolic diseases.
Yu-Ching Chou, San-Lin You, Chyi-Huey Bai, Yu-Chan Liao, Cheng-Yu Wei, Chien-An Sun   +5 more
doaj  

Measurement of Plasma Apolipoprotein A-I and B in Hyperlipidemic Subjects

, 1976
Shunichi KOGA, Kenjiro IKEDA, Hiroshi Ibayashi   +2 more
openalex   +2 more sources

Amyloid‐Related Imaging Abnormality (ARIA) Beyond the APOE‐ε4 Allele

Chronic Diseases and Translational Medicine, EarlyView.
Mechanism of action of monoclonal antibodies targeting Aβ in the treatment of AD. (A) Targets of various mAbs. (B) Mechanism of monoclonal antibody‐mediated clearance of Aβ. mAbs facilitate the clearance of Aβ by enhancing microglial‐mediated phagocytosis through the upregulation of TREM2 expression.
Valentinus Besin, Farizky Martriano Humardani, Fenny Lanawati Yudiarto, Paulus Anam Ong, Sulistyo Emantoko Dwi Putra, Ratih Asmana Ningrum   +5 more
wiley   +1 more source

Apolipoprotein E polymorphism alters the association between body fatness and plasma lipoproteins in women.

Journal of Lipid Research, 1990
The aim of the present study was to investigate the associations between total adiposity, body fat distribution, and plasma lipoprotein levels within groups of women defined on the basis of apolipoprotein E phenotypes, in order to verify whether apoE ...
MC Pouliot, JP Després, S Moorjani, PJ Lupien, A Tremblay, C Bouchard   +5 more
doaj  

Standardization of Apolipoprotein B, LDL-Cholesterol, and Non-HDL-Cholesterol. [PDF]

J Am Heart Assoc, 2023
Contois JH, Langlois MR, Cobbaert C, Sniderman AD.   +3 more
europepmc   +1 more source

Concentrations of Lipids and Apolipoprotein B in Plasma and Lipoprotein Density Classes from Japanese Umbilical Cord Blood

, 1979
Toshitaka TAMAI, Tsuguhiko NAKAI, Shiro YAMADA, Takeshi Kobayashi, Takio YAYASHI, Hasunori KUTSUMI, Ryoyu Takeda   +6 more
openalex   +2 more sources

Model‐Informed Drug Development Applications and Opportunities in mRNA‐LNP Therapeutics

Clinical Pharmacology &Therapeutics, EarlyView.
The utilization of lipid nanoparticles (LNP) for encapsulating mRNA has revolutionized the field of therapeutics, enabling the rapid development of COVID‐19 vaccines and cancer vaccines. However, the clinical development of mRNA‐LNP therapeutics faces numerous challenges due to their complex mechanisms of action and limited clinical experience.
Jiawei Zhou, Rohit Rao, Monica E. Shapiro, Nessy Tania, Cody Herron, Cynthia J. Musante, Jim H. Hughes   +6 more
wiley   +1 more source

Findings of 18F‐PI‐2620 tau PET imaging in patients with Alzheimer’s disease and healthy controls in relation to the plasma P‐tau181 levels in a Japanese sample

Neuropsychopharmacology Reports, Volume 42, Issue 4, Page 437-448, December 2022., 2022
The present pilot study examined the ability of 18F‐PI‐2620 tau PET tracer to distinguish between healthy control and Alzheimer's disease, as well as correlations with plasma p‐tau181 and cognitive test results. Though the sample size was small, seven for each group, its SUVR in the target brain regions showed distinct differences between them and high
Shogyoku Bun, Sho Moriguchi, Toshiki Tezuka, Yoshiaki Sato, Keisuke Takahata, Morinobu Seki, Shinichiro Nakajima, Yasuharu Yamamoto, Yasunori Sano, Natsumi Suzuki, Ayaka Morimoto, Ryo Ueda, Hajime Tabuchi, Daisuke Ito, Masaru Mimura   +14 more
wiley   +1 more source

The association between blood lipids and cognitive impairment in type 2 diabetes mellitus

European Journal of Medical Research
Objective The study was performed to explore the association between blood lipids and cognitive impairment in patients with type 2 diabetes mellitus (T2DM). Methods This study included 336 patients with T2DM.
Li Ma, Yue-Xing Yuan, Feng-Jin Cheng, Yan Liu, Qiong Wei, You-Fan Peng, Yao Wang   +6 more
doaj   +1 more source

Use of Apolipoprotein B in the Era of Precision Medicine: Time for a Paradigm Change? [PDF]

J Clin Med, 2023
Cole J, Zubirán R, Wolska A, Jialal I, Remaley AT.   +4 more
europepmc   +1 more source