Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease
Abstract Objective Endothelial dysfunction is an early and prevalent pathology in Alzheimer disease (AD). We here investigate the value of vascular endothelial‐cadherin (VEC) as a cerebrospinal fluid (CSF) marker of endothelial injury in preclinical AD.
Rawan Tarawneh+5 more
wiley +1 more source
Dabigatran and apolipoprotein B [PDF]
Dabigatran is the first of a series of new direct acting oral anticoagulants that was clinically introduced for the prevention of ischaemic stroke in patients with atrial fibrillation (AF). In the randomized evaluation of long-term anticoagulation therapy (RE-LY) study, dabigatran was shown to be superior or non-inferior to warfarin in preventing ...
openaire +3 more sources
The association between the apolipoprotein B/A-I ratio and coronary calcification may differ depending on kidney function in a healthy population. [PDF]
The apolipoprotein B/A-1 ratio has been reported to be one of the strongest risk predictors of cardiovascular events. However, its prognostic value for cardiovascular disease is still uncertain, especially in patients with chronic kidney disease.
Seok-Hyung Kim+9 more
doaj +1 more source
Degradation of human apolipoprotein B‐100 by apolipoprotein(a)
Human plasma low density lipoproteine (LDL) contain a very high molecular weight protein termed apoB‐100 (M r = 550,000). In many samples of LDL, minor components designated as apoB‐74 (M r = 407,000) and apoB‐26 (M r = 145,000) are present. It has been shown that they can arise as a result of proteolytic degradation of apoB‐100.
V.V. Tertov, T.M. Chulkova
openaire +3 more sources
Apolipoprotein B Is Associated With the Microenvironment of Cholangiocarcinoma [PDF]
BackgroundCholangiocarcinoma (CCA) is a kind of devastating malignancy, which is correlated with the extremely high mortality. Due to the occult pathogenesis of CCA, most patients are diagnosed in the advanced stage. However, the efficacy of chemotherapy and immunotherapy is limited for these patients.
Xiaofeng Xu+17 more
openaire +3 more sources
Apolipoprotein[a] is not associated with apolipoprotein B in human liver
The aim of this research was to determine whether apolipoprotein[a] (apo[a]) is linked to apolipoprotein B (apoB) in human liver. Four ELISAs were developed: 1) a competition assay that measures apoB; 2) a competition assay that measures apo[a]; 3) a capture assay based on capture of apo[a] by a polyclonal antibody and detection of co-immobilized apoB ...
Lisa H. Munro+2 more
openaire +3 more sources
Background The apolipoprotein E (ApoE) gene polymorphisms are correlated with blood lipid levels and several neuropsychiatric symptoms. Therefore, this study aimed to examine whether the ApoE rs429358 affected the development and clinical symptoms of ...
Wenwang Rao+4 more
doaj +1 more source
The role of APOBEC3-induced mutations in the differential evolution of monkeypox virus [PDF]
Recent studies show that newly sampled monkeypox virus (MPXV) genomes exhibit mutations consistent with Apolipoprotein B mRNA Editing Catalytic Polypeptide-like3 (APOBEC3)-mediated editing, compared to MPXV genomes collected earlier. It is unclear whether these single nucleotide polymorphisms (SNPs) result from APOBEC3-induced editing or are a ...
arxiv
KADAR APOLIPOPROTEIN B 100 SERUM PADA PENDERITA NEFROPATI DIABETIKUM
AbstrakPenelitian ini bertujuan untuk mengetahui kadar Apolipoprotein B 100 serum pada penderita nefropati diabetikum. Metode penelitian ini dengan desain cross sectional yang bersifat deskriptif analitik.
Eva Decroli
doaj +1 more source
Clinical significance of fasting and postprandial lipemia in obese and non-obese subjects [PDF]
Background and objective: Postprandial lipemia is a risk marker for the presence or progression of cardiovascular disease. Identifying factors affecting lipoprotein metabolism in postprandial state is of interest in order to find ways for prevention of ...
Muzha M. Baqi+1 more
doaj +1 more source