Results 11 to 20 of about 13,105,697 (337)

Familial defective apolipoprotein B-100: a mutation of apolipoprotein B that causes hypercholesterolemia.

Journal of Lipid Research, 1990
Familial defective apolipoprotein B-100 is a genetic disorder of apolipoprotein B-100 that causes moderate to severe hypercholesterolemia. A single amino acid mutation in apolipoprotein B diminishes the ability of low density lipoproteins to bind to the ...
TL Innerarity, RW Mahley, KH Weisgraber, TP Bersot, RM Krauss, GL Vega, SM Grundy, W Friedl, J Davignon, BJ McCarthy   +9 more
doaj   +4 more sources

The correlation of apolipoprotein B, apolipoprotein B/apolipoprotein A-I ratio and lipoprotein(a) with myocardial infarction

Open Medicine, 2008
Abstract Recent evidence shows that apolipoprotein (apo) B, apoB/apoA-I ratio and lipoprotein(a) are better indicators of coronary risk than the conventional lipid profile. The aim of this study was to evaluate the correlation of apoA-I and B, and lipoprotein(a) with myocardial infarction (MI).
Agoston-Coldea Lucia, Mocan Teodora, Gatfossé Marc, Dumitrascu Dan   +3 more
doaj   +3 more sources

Effects of overexpression of the amino-terminal fragment of apolipoprotein B on apolipoprotein B and lipoprotein production [PDF]

Journal of Lipid Research, 2000
In vitro studies have shown that the binding site for microsomal triglyceride transfer protein (MTP) is within the first 17% of apoB (apoB-17). Expression of apoB-48 in McArdle cells decreases endogenous lipoprotein production; however, overexpression of
Zhaohui Li, Yuko Kako, Ling Pang, Mason W. Freeman, Jane M. Glick, Xinzhong Wang, Ira J. Goldberg   +6 more
doaj   +4 more sources

Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B.

New England Journal of Medicine, 1990
BACKGROUND AND METHODS The effect of intensive lipid-lowering therapy on coronary atherosclerosis among men at high risk for cardiovascular events was assessed by quantitative arteriography.
Greg B. Brown, J. Albers, L. Fisher, Susan M. Schaefer, Jiin-Tarng Lin, Cheryl Kaplan, X. Zhao, Brad D. Bisson, V. Fitzpatrick, H. Dodge   +9 more
semanticscholar   +1 more source

Apolipoprotein B Particles and Cardiovascular Disease: A Narrative Review.

JAMA cardiology, 2019
Importance The conventional model of atherosclerosis presumes that the mass of cholesterol within very low-density lipoprotein particles, low-density lipoprotein particles, chylomicron, and lipoprotein (a) particles in plasma is the principal determinant
A. Sniderman, G. Thanassoulis, Tamara Glavinovic, A. Navar, M. Pencina, A. Catapano, B. Ference   +6 more
semanticscholar   +1 more source

Dabigatran and apolipoprotein B [PDF]

Heart, 2015
Dabigatran is the first of a series of new direct acting oral anticoagulants that was clinically introduced for the prevention of ischaemic stroke in patients with atrial fibrillation (AF). In the randomized evaluation of long-term anticoagulation therapy (RE-LY) study, dabigatran was shown to be superior or non-inferior to warfarin in preventing ...
openaire   +3 more sources

Association of Apolipoprotein B and Triglyceride Levels with Coronary Artery Disease

Pakistan Armed Forces Medical Journal, 2022
Objective: To find the association of Apolipoprotein B and triglycerides with coronary artery disease. Study Design: Cross-sectional study. Place and Duration of Study: Department of Chemical Pathology and Endocrinology, Armed Forces Institute of ...
Hunain Habib, Zujaja Hina Haroon, Muhammad Aamir, Afshan Bibi, Haroon Javed, Syed Raza Jaffer   +5 more
doaj   +1 more source

Association between clinical symptoms and apolipoprotein A1 or apolipoprotein B levels is regulated by apolipoprotein E variant rs429358 in patients with chronic schizophrenia

Annals of General Psychiatry, 2021
Background The apolipoprotein E (ApoE) gene polymorphisms are correlated with blood lipid levels and several neuropsychiatric symptoms. Therefore, this study aimed to examine whether the ApoE rs429358 affected the development and clinical symptoms of ...
Wenwang Rao, Xiangfei Meng, Keqing Li, Yunshu Zhang, Xiang Yang Zhang   +4 more
doaj   +1 more source

Trends in Levels of Lipids and Apolipoprotein B in US Youths Aged 6 to 19 Years, 1999-2016.

Journal of the American Medical Association (JAMA), 2019
Importance Favorable trends occurred in the lipid levels of US youths through 2010, but these trends may be altered by ongoing changes in the food supply, obesity prevalence, and other factors.
Amanda M. Perak, Hongyan Ning, Brian K. Kit, S. D. de Ferranti, L. V. Van Horn, J. Wilkins, D. Lloyd‐Jones   +6 more
semanticscholar   +1 more source

The association between the apolipoprotein B/A-I ratio and coronary calcification may differ depending on kidney function in a healthy population. [PDF]

PLoS ONE, 2017
The apolipoprotein B/A-1 ratio has been reported to be one of the strongest risk predictors of cardiovascular events. However, its prognostic value for cardiovascular disease is still uncertain, especially in patients with chronic kidney disease.
Seok-Hyung Kim, Donghwan Oh, Kwon Soo Jung, Jung Eun Lee, Hyunwook Kim, Hyung Jong Kim, Beom Seok Kim, Hyeong Cheon Park, Byoung Kwon Lee, Hoon Young Choi   +9 more
doaj   +1 more source