Results 31 to 40 of about 123,719 (312)

Heterogeneous Apolipoprotein B Response to the Paleolithic Diet in South Asian Adults: A Novel Phenotypic Pattern

Journal of Health Science and Medical Research (JHSMR)
Objective: While European-ancestry populations demonstrate consistent apolipoprotein B elevation on low-carbohydrate diets, South Asian responses remain unexplored.
Vijayasamundeeswari Chinnathambipalayam Kandaswamy, Hariharan Venkatasubramanian   +1 more
doaj   +1 more source

Familial defective apolipoprotein B-100: a mutation of apolipoprotein B that causes hypercholesterolemia.

Journal of Lipid Research, 1990
Familial defective apolipoprotein B-100 is a genetic disorder of apolipoprotein B-100 that causes moderate to severe hypercholesterolemia. A single amino acid mutation in apolipoprotein B diminishes the ability of low density lipoproteins to bind to the ...
TL Innerarity, RW Mahley, KH Weisgraber, TP Bersot, RM Krauss, GL Vega, SM Grundy, W Friedl, J Davignon, BJ McCarthy   +9 more
doaj   +1 more source

Selection on Alleles Affecting Human Longevity and Late-Life Disease: The Example of Apolipoprotein E

, 2010
It is often claimed that genes affecting health in old age, such as cardiovascular and Alzheimer diseases, are beyond the reach of natural selection. We show in a simulation study based on known genetic (apolipoprotein E) and non-genetic risk factors ...
Kirkwood Thomas B. L., Drenos Fotios, Drenos, F, Kirkwood, TBL, Fotios Drenos, Thomas B L Kirkwood   +5 more
core   +1 more source

Lipid transfer proteins in the assembly of apoB-containing lipoproteins

Journal of Lipid Research, 2018
A better understanding of intracellular lipoprotein assembly may help identify proteins with important roles in lipid disorders. apoB-containing lipoproteins (B-lps) are macromolecular lipid and protein micelles that act as specialized transport vehicles
Alaa Sirwi, M.Mahmood Hussain
doaj   +1 more source

Lumican silencing ameliorates β-glycerophosphate-mediated vascular smooth muscle cell calcification by attenuating the inhibition of APOB on KIF2C activity

Open Medicine, 2023
Adverse cardiovascular events are associated with vascular calcification (VC) process, where vascular smooth muscle cells (VSMCs) differentiate into osteoblastic phenotype and deposit hydroxyapatite crystals. Microtubule-associated protein kinesin family
Li Haibin, Zhang Chunyan, Liu Qiang
doaj   +1 more source

Effects of inhibiting cholesterol absorption and synthesis on cholesterol and lipoprotein metabolism in hypercholesterolemic non-insulin-dependent diabetic men.

Journal of Lipid Research, 1996
Effectiveness of a simultaneous inhibition of cholesterol absorption and synthesis, caused by sitostanol ester margarine and pravastatin, was studied to control mild hypercholesterolemia in men with non-insulin-dependent diabetes mellitus (NIDDM) (n = 8).
H Gylling, T A Miettinen
doaj   +1 more source

Association of Early Renal Dysfunction with Lipid Profile Parameters among Hypertensives in Kazakhstan

Diagnostics, 2021
Dyslipidemia plays an essential role in chronic kidney disease (CKD). The role of lipids and lipoproteins in the early pre-disease state of CKD in hypertensive patients is still unclear.
Alma Nurtazina, Dana Kozhakhmetova, Daulet Dautov, Nurzhanat Khaidarova, Vijay Kumar Chattu   +4 more
doaj   +1 more source

Apolipoprotein-B effects on hematological indices (per 10-mg/dL increment).

, 2018
Apolipoprotein-B effects on hematological indices (per 10-mg/dL increment).
Chang-Hsien Lu (5587577), Chih-Cheng Chen (261490), Ming-Chung Wang (5587571), Hsing-Yi Tsou (5587586), Meng-Hung Lin (1894504), Ping-Tsung Chen (5587580), Chia-Chen Hsu (438579), Cih-En Huang (5587574), Yao-Hsu Yang (441809), Yu-Ying Wu (5587583)   +9 more
core   +1 more source

Evidence based diabetology : strategies to prevent macrovascular disease and to reduce mortality [PDF]

, 2006
Diabetes mellitus (DM) is the most common metabolic disease worldwide and the number of newly diagnosed cases is increasing. DM is strongly associated with a number of devastating chronic late complications, including retinopathy, nephropathy and ...
Allemann, Sabin Liliane
core   +1 more source

Quantification of apolipoprotein E receptors in human brain-derived cell lines by real-time polymerase chain reaction

, 2004
Apolipoprotein (apo) E4 is a risk factor for Alzheimer's disease (AD) and other neurodegenerative diseases, compared to wild-type apoE3. The mechanism(s) is unknown.
Owen, JS, Everett, D M, Murdock, P R, Everett, DM, Murdock, PR, Owen, J S, Dingwall, C, Thilakawardhana, S   +7 more
core   +1 more source