Results 271 to 280 of about 13,195,946 (379)

Proteomic Insight Into Alzheimer's Disease Pathogenesis Pathways

PROTEOMICS, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a leading cause of dementia, but the pathogenesis mechanism is still elusive. Advances in proteomics have uncovered key molecular mechanisms underlying AD, revealing a complex network of dysregulated pathways, including amyloid metabolism, tau pathology, apolipoprotein E (APOE), protein degradation ...
Taekyung Ryu, Kyungdo Kim, Nicholas Asiimwe, Chan Hyun Na   +3 more
wiley   +1 more source

Apolipoprotein-B mRNA-editing complex 3B could be a new potential therapeutic target in endometriosis. [PDF]

Sci Rep
Vu TH, Nakamura K, Shigeyasu K, Kashino C, Okamoto K, Kubo K, Kamada Y, Masuyama H.   +7 more
europepmc   +1 more source

Structural organization of apolipoprotein B-100 of human plasma low density lipoproteins. Comparison to B-48 of chylomicrons and very low density lipoproteins.

, 1986
A D Cardin, Christopher A. Price, Nobuyoshi Hirose, Michèle A. KRIVANEK, Dale T. Blankenship, Julie Chao, Shuqi Mao   +6 more
openalex   +1 more source

Influence of apolipoprotein E polymorphism on apolipoprotein B-100 metabolism in normolipemic subjects. [PDF]

, 1991
Thomas Demant, Dorothy Bedford, Chris J. Packard, J Shepherd   +3 more
openalex   +1 more source

Plasma Proteomic Profiling of a Group of Anxious Dogs by LC‐MS/MS: A Case–Control Study

PROTEOMICS – Clinical Applications, EarlyView.
ABSTRACT Purpose Anxiety is the most common underlying cause of behavioral problems in dogs, which remain a top reason for relinquishment and euthanasia. Despite its high prevalence, anxiety is often underdiagnosed, partly due to a limited understanding of biological processes and absence of diagnostic biomarkers.
Claudia Gaither, Robert Popp, Christoph H. Borchers, Francis Beaudry, Marion Desmarchelier   +4 more
wiley   +1 more source

Longitudinal analysis of adiponectin to leptin and apolipoprotein B to A1 ratios as markers of future airflow obstruction and lung function decline. [PDF]

Sci Rep
Kim S, Rhee CK, Jo YS, Lim JU, Kim SH, Yoo J, Choi JY.   +6 more
europepmc   +1 more source

A Multimarker Model for Prostate Cancer Risk Assessment: Improving Diagnostic Accuracy Beyond PSA

The Prostate, EarlyView.
ABSTRACT Objective This study aimed to evaluate the association between biochemical markers and prostate cancer (PCa) risk by analyzing patients with benign prostatic hyperplasia (BPH) and PCa. Additionally, the study sought to assess the diagnostic accuracy of a multimarker model compared to prostate‐specific antigen (PSA) alone.
Penglu Yang, Bin Yang
wiley   +1 more source

Apolipoprotein B and Lipid Profile in Italian Children and Adolescents. [PDF]

J Cardiovasc Dev Dis
Martino F, Niglio T, Martino E, Paravati V, de Sanctis L, Guardamagna O.   +5 more
europepmc   +1 more source

Apolipoprotein B-100 of plasma low density lipoproteins undergoes proteolysis by contact activation factors when plasma is treated with dextran sulfate-500-MgCl2.

, 1989
R E Byrne, A M Scanu
openalex   +1 more source

Population Pharmacokinetics and Exposure‐Response Modeling for Evinacumab in Children, Adolescents, and Adults With Homozygous Familial Hypercholesterolemia

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Evinacumab, an angiopoietin‐like 3 (ANGPTL3) inhibitor, significantly reduces low‐density lipoprotein cholesterol (LDL‐C), independent of low‐density lipoprotein receptor, in patients with homozygous familial hypercholesterolemia (HoFH). A population pharmacokinetic (PK)/pharmacodynamic (PD) model was previously developed to characterize ...
Sébastien Bihorel, Robert Dingman, Jeanne Mendell, Yuhuan Wang, Poulabi Banerjee, Robert Pordy, John D. Davis, A. Thomas DiCioccio, Lutz Harnisch   +8 more
wiley   +1 more source