Results 221 to 230 of about 73,331 (301)

Therapeutic Potential of Berberis vulgaris in Modulating Metabolic Syndrome Biomarkers: Mechanistic Insights and Functional Food Implications

Food Frontiers, Volume 7, Issue 4, July 2026.
ABSTRACT Barberry (Berberis vulgaris) has emerged as a promising functional food candidate for the management of metabolic syndrome due to its diverse bioactive constituents, particularly berberine. This review synthesizes current experimental and clinical evidence regarding its effects on glycemic control, lipid metabolism, blood pressure regulation ...
Fakhar Shahid, Ifrah Jabeen, Muhammad Inam‐ur‐Raheem, Amin Mousavi Khaneghah, Muhammad Abid, Rana Muhammad Aadil   +5 more
wiley   +1 more source

Apolipoprotein A-I (CSL112) and Cardiovascular Outcomes in Atherosclerotic Cardiovascular Disease: A Scoping Review. [PDF]

Clin Cardiol
Habib A, Khan MSM, Aneeq A, Tahir HMT, Mehmoodi A, Malik J, Perveen A.   +6 more
europepmc   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, Volume 46, Issue 4, Page 1173-1229, July 2026.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Fecal Proteomics Suggest Potential Biomarkers for Non‐Alcoholic Fatty Liver Disease and Steatohepatitis

PROTEOMICS – Clinical Applications, Volume 20, Issue 4, July 2026.
ABSTRACT Background and aims Non‐alcoholic Fatty Liver Disease (NAFLD) affects about a quarter of the world's population. Liver biopsy remains the gold standard for diagnosing the progressive form of NAFLD called Non‐alcoholic Steatohepatitis (NASH) but it is invasive, prone to sampling errors and observer variability, and impractical for widespread ...
Anna Negroni, Luisa Pieroni, Noemi Fiaschini, Francesca Palone, Mariateresa Mancuso, Roberta Vitali   +5 more
wiley   +1 more source

Updates on Mediterranean diet and health status: active ingredients and pharmacological mechanisms

British Journal of Pharmacology, Volume 183, Issue 13, Page 3484-3502, July 2026.
The Mediterranean diet (MedDiet) is among the most extensively studied dietary patterns and has been consistently associated with reduced risk of all‐cause mortality, cardiovascular disease, metabolic disorders, cognitive decline and several types of cancers.
Lukas Schwingshackl, Jakub Morze, Sabina Wallerer, Georg Hoffmann   +3 more
wiley   +1 more source

Dynamics of Apolipoprotein J Levels and Metabolic Parameters Following Bariatric Surgery

Clinical Endocrinology, Volume 105, Issue 1, Page 42-50, July 2026.
ABSTRACT Objective Bariatric surgery has emerged as a potent intervention for ameliorating insulin resistance and its associated comorbidities in obese patients. Apolipoprotein J (ApoJ) and adiponectin are closely associated with insulin resistance and sensitivity, respectively.
Kellen Cristina da Cruz Rodrigues, Minjin Lee, Yejee Lim, Jennie Young, Brendon Chung, Susan Phillips, Theodore P. Ciaraldi, Young‐Bum Kim   +7 more
wiley   +1 more source

Baseline NMR lipoprotein profiles in lithium-naïve bipolar disorder patients who later showed weight gain during lithium therapy: a pilot study. [PDF]

Int J Bipolar Disord
Schönthaler E, Fellendorf FT, Madl T, Habisch H, Bengesser S, Dalkner N, Fleischmann E, Georgi J, Häussl A, Hasic D, Ilic J, Lässer A, Lenger M, Maget A, Mittmannsgruber C, Popkova D, Queissner R, Ramirez-Obermayer A, Smolle S, Stross T, Tmava-Berisha A, Reininghaus EZ.   +21 more
europepmc   +1 more source

Cold‐Induced Lipidomic Remodelling Is Associated With Brown Adipose Tissue Mean Radiodensity in Humans

Diabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5810-5826, July 2026.
ABSTRACT Aims Cold exposure activates brown adipose tissue (BAT) and promotes thermogenic and metabolic adaptations. While BAT activation has been linked to improved cardiometabolic health, how acute cold exposure reshapes the circulating lipidome in humans remains incompletely understood.
Yu Zhang, Borja Martinez‐Tellez, Alida Kindt, Nicolas Drouin, Amy Harms, Thomas Hankemeier, Jonatan R. Ruiz, Lucas Jurado‐Fasoli   +7 more
wiley   +1 more source

Cerebrospinal fluid CEFA composition is enriched in saturated fatty acids and it is altered in Alzheimer's disease. [PDF]

J Lipid Res
Pavanello C, Ossoli A, Comi C, Turri M, Tremolizzo L, Conti E, D'Incecco P, Barbiroli A, Parini P, Mitro N, Caruso D, Sierri G, Re F, Chinello C, Fumagalli C, Magni F, Fernandes K, Calabresi L.   +17 more
europepmc   +1 more source

Blood biomarkers of Alzheimer's disease and 15‐year decline in cognitive and motor functions in older adults

Journal of Internal Medicine, Volume 300, Issue 1, Page 64-77, July 2026.
Abstract Background Individuals showing concurrent and rapid declines in cognitive and motor performance (i.e., dual decliners) are at increased risk of faster progression to dementia. Still, the role of Alzheimer's disease (AD) pathology in motor/cognitive joint trajectories remains poorly understood.
Elena Pinardi, Giulia Grande, Alice Margherita Ornago, Martina Valletta, Debora Rizzuto, Claudia Fredolini, Matilda Dale, Erika J. Laukka, Patrizia Mecocci, Bengt Winblad, Laura Fratiglioni, Giuseppe Bellelli, Davide Liborio Vetrano   +12 more
wiley   +1 more source