Results 291 to 300 of about 195,708 (344)

LJ-1888, a selective antagonist for the A3 adenosine receptor, ameliorates the development of atherosclerosis and hypercholesterolemia in apolipoprotein E knock-out mice [PDF]

, 2018
Jeong, Lak Shin, Jeong, Se-Jin, Kim, Gyudong, Oh, Goo Taeg, Park, Jong-Gil, Yu, Jinha   +5 more
core   +1 more source

Human amyotrophic lateral sclerosis/motor neuron disease: The disease‐associated microglial pathway is upregulated while APOE genotype governs risk and survival

Brain Pathology, EarlyView.
ALS/MND‐related inflammation is investigated in the motor cortex and spinal cord by both transcriptomics and immunohistochemistry. This reveals greater inflammation in the spinal cord and highlights the disease‐associated microglial (DAM) phenotype characterized by ApoE, TREM2, and TYROBP.
Bridget A. Ashford, Julie E. Simpson, Charlotte Dawson, Delphine Boche, Johnathan Cooper‐Knock, Paul R. Heath, Daniel Fillingham, Charlie Appleby‐Mallinder, Wenbin Wei, Mark Dunning, J. Robin Highley   +10 more
wiley   +1 more source

Apolipoprotein E-ε4 allele is associated with perihematomal brain edema and poor outcomes in patients with intracerebral hemorrhage. [PDF]

Sci Rep
Huang L, Wu Q, Ye F, Che W, Zhao X, Yang C, Ren S, Wu G, Wang L.   +8 more
europepmc   +1 more source

Independent associations of TOMM40 and APOE variants with body mass index [PDF]

, 2019
Arbeev, Konstantin G, Bagley, Olivia, Christensen, Kaare, Culminskaya, Irina, Feitosa, Mary F, Huang, Jian, Kulminski, Alexander M, Loika, Yury, Long Life Family Study Research Group,, Yashin, Anatoliy I, Zmuda, Joseph M   +10 more
core   +1 more source

Impact of Apolipoprotein E ε4 in Alzheimer's Disease: Insights From a Meta-Analysis. [PDF]

J Clin Neurol
Kwon HS, Koh SH.
europepmc   +1 more source

The First Japanese Case of Familial Hypercholesterolemia Caused by an apolipoprotein E (APOE) p.Leu167del Mutation. [PDF]

Intern Med
Tada H, Nomura A, Kawashiri MA, Takamura M.   +3 more
europepmc   +1 more source

Genome-wide association studies of Alzheimer's disease and related disorders stratified by sex, onset age, and Apolipoprotein E genotype reveal novel risk loci in African Americans. [PDF]

Alzheimers Res Ther
Sherva R, Zhu C, Zhang R, Mez J, Hauger R, Merritt VC, Panizzon M, Gaziano JM, Catanzaro V, Schellenberg GD, Pericak-Vance M, Haines JL, Wang LS, Mayeux R, VA Million Veteran Program, Farrer LA, Logue MW.   +16 more
europepmc   +1 more source