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Apolipoprotein E dysfunction in Alzheimer's disease: a study on miRNA regulation, glial markers, and amyloid pathology. [PDF]
Front Aging NeurosciWijesinghe P +7 more
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Apolipoprotein E--Correction [PDF]
Neurology, 1995 To the Editor: We made three major points in our paper [1] published in the August 1994 issue of Neurology. First, we found that two of 28 cognitively normal people over the age of 90 had inherited the apolipoprotein E (ApoE) epsilon4 allele (see table 1 in reference 1). This suggests that it is possible to …
G. William Rebeck, Bradley T. Hyman
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Apolipoprotein E and Atherosclerosis
Current Atherosclerosis Reports, 2021The functions, genetic variations and impact of apolipoprotein E on lipoprotein metabolism in general are placed in the context of clinical practice dealing with moderate dyslipidaemia as well as dysbetalipoproteinemia, a highly atherogenic disorder and lipoprotein glomerulopathy.Additional variants of apolipoprotein E and participation of ...
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Apolipoprotein E and the Apolipoprotein E-Deficient Mouse
Annual Review of Nutrition, 1995Apolipoprotein E (apoE) is one of several lipoprotein transfer genes. A primary function of this protein is the mediation of receptor-mediated lipoprotein removal from the blood. Several studies have demonstrated that genetic variation at the apoE locus is associated with an increased risk of developing atherosclerosis, and recent studies implicate ...
Jan L. Breslow, Andrew S. Plump
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Apolipoprotein E and atherosclerosis
Current Opinion in Lipidology, 2000Apolipoprotein E plays a key protective role in atherosclerosis. Its capacity to safeguard against this disease can be attributed to at least three distinct functions. First, plasma apolipoprotein E maintains overall plasma cholesterol homeostasis by facilitating efficient hepatic uptake of lipoprotein remnants.
Linda K. Curtiss, William A. Boisvert
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Apolipoprotein E in Hyperlipidemia
Annals of Internal Medicine, 1994To review DNA analysis of apolipoprotein E used to assess patients with hyperlipidemia.44 basic science studies of molecular analysis; 42 basic science studies of the biochemical, cellular biological, and molecular biological features of apolipoprotein E; and 29 clinical investigational studies, meta-analyses, and case series of patients with mutations
Robert A. Hegele, Cristina C. Walden
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Apolipoprotein in E in Myasthenia Gravis
Annals of the New York Academy of Sciences, 1998It is believed that apo E may moderate T lymphocytes by activation of mitogens or antigens. In that way, it has an influence on immune processes and it is reasonable to study the relationship between apo E genotypes and myasthenia gravis phenotypes. We tried to find any feature connected to the development of a different intensity of myasthenia gravis.
Marija Šoštarko +5 more
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