Results 191 to 200 of about 40,273 (244)

Long‐term alcohol consumption and incident health risk conditions related to cardiometabolic risk markers: A 20‐year prospective cohort study

Addiction, EarlyView.
Abstract Background and aims Amid questions about a perceived association between low‐to‐moderate alcohol consumption and reduced cardiovascular risk from recent studies, research examining the impact of alcohol consumption on cardiometabolic risk markers has reported inconsistent results.
Sooyeun Choi, Taeyoung Park, Youjin Je
wiley   +1 more source

Effects of phytosterol supplementation on lipid profiles and apolipoproteins: A meta-analysis of randomized controlled trials. [PDF]

Medicine (Baltimore)
Zhang YF, Qiao W, Feng H, Jiang K, Yang J, Zhou T, Zhang Y.   +6 more
europepmc   +1 more source

Incorporating familial risk, lifestyle factors, and pharmacogenomic insights into personalized noncommunicable disease (NCD) reports for healthcare funder beneficiaries participating in the Open Genome Project

Annals of Human Genetics, EarlyView.
Abstract Introduction An ethics‐guided decision‐making framework was developed for applying pathology‐supported genetic testing, a multifaceted pharmacodiagnostic approach that translates population risk stratification into clinical utility. We introduce this service, supported by the Open Genome Project, which aligns with the beneficence principle in ...
Manie De Klerk, Nicole Van Der Merwe, Johny Erasmus, Lindiwe Whati, Kelebogile E. Moremi, Daniel W. Olivier, Maritha J. Kotze   +6 more
wiley   +1 more source

Divergent Roles of APOAI and APOM in the Identification of Alcohol Use Disorder and Their Association With Inflammation and Cognitive Decline: A Pilot Study. [PDF]

Int J Neuropsychopharmacol
Escudero B, López-Valencia L, Arias Horcajadas F, Orio L.   +3 more
europepmc   +1 more source

Genetic Determinants of the Familial Hypercholesterolaemia Phenotype

Annals of Human Genetics, EarlyView.
ABSTRACT Individuals with familial hypercholesterolaemia (FH) have severely elevated plasma concentrations of low‐density lipoprotein cholesterol (LDL‐C) from birth and as a consequence have an elevated morbidity and mortality due to the development of coronary heart disease (CHD).
Steve Eric Humphries, Marta Futema
wiley   +1 more source

Understanding the heterogeneity and dysfunction of HDL in chronic kidney disease: insights from recent reviews. [PDF]

BMC Nephrol
Xu Z, Yang S, Cui L.
europepmc   +1 more source

Systematic Review of Rare Major Adverse Cardiovascular Events Associated With the Treatment of Acne With Isotretinoin

Australasian Journal of Dermatology, Volume 66, Issue 3, Page e97-e108, May 2025.
ABSTRACT Acne vulgaris is a common inflammatory condition that is often treated by dermatologists with isotretinoin. Isotretinoin has a number of effects on inflammatory pathways, with clear efficacy in managing acne vulgaris. There are also well‐documented side effects of isotretinoin, including hyperlipidemia; however, the overall cardiovascular risk
Timothy L. Cowan, Madeleine Stark, Simona Sarmiento, Andrew Miller   +3 more
wiley   +1 more source

Challenges and opportunities for statistical power and biomarker identification arising from rhythmic variation in proteomics. [PDF]

NPJ Biol Timing Sleep
Spick M, Isherwood CM, Gethings LA, Hughes CJ, Daly ME, Hassanin H, van der Veen DR, Skene DJ, Johnston JD.   +8 more
europepmc   +1 more source

Engineered nanoparticles potentials in male reproduction

Andrology, Volume 13, Issue 4, Page 694-705, May 2025.
Abstract Background The escalating prevalence of fertility problems in the aging population necessitates a comprehensive exploration of contributing factors, extending beyond environmental concerns, work‐related stress, and unhealthy lifestyles. Among these, the rising incidence of testicular disorders emerges as a pivotal determinant of fertility ...
Feifei Zhao, Mengyu Fan, Zhiyang Jing, Yanxu Zhang, Yanlin Wang, Congli Zhou, Yang Liu, Robert John Aitken, Xue Xia   +8 more
wiley   +1 more source

Association between Apolipoprotein B and diabetic nephropathy: insights from the National Health and Nutrition Examination Survey 2007-2016 and Mendelian randomization analysis. [PDF]

Nutr Diabetes
Wang H, Wu S, Pan D, Ning Y, Fu Y, Feng C, Guo J, Liu Z, Gu Y.   +8 more
europepmc   +1 more source