Results 321 to 330 of about 18,826,161 (368)
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Apolipoprotein E in Hyperlipidemia
Annals of Internal Medicine, 1994To review DNA analysis of apolipoprotein E used to assess patients with hyperlipidemia.44 basic science studies of molecular analysis; 42 basic science studies of the biochemical, cellular biological, and molecular biological features of apolipoprotein E; and 29 clinical investigational studies, meta-analyses, and case series of patients with mutations
Robert A. Hegele, Cristina C. Walden
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Arteriosclerosis, Thrombosis and Vascular Biology, 1996
Nonrheumatic aortic stenosis of trileaflet aortic valves has been considered to be a "degenerative" process, but the early lesion of aortic stenosis contains the chronic inflammatory cells, macrophages and T lymphocytes. Because lipoprotein deposition is
K. O’Brien +5 more
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Nonrheumatic aortic stenosis of trileaflet aortic valves has been considered to be a "degenerative" process, but the early lesion of aortic stenosis contains the chronic inflammatory cells, macrophages and T lymphocytes. Because lipoprotein deposition is
K. O’Brien +5 more
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Apolipoprotein in E in Myasthenia Gravis
Annals of the New York Academy of Sciences, 1998It is believed that apo E may moderate T lymphocytes by activation of mitogens or antigens. In that way, it has an influence on immune processes and it is reasonable to study the relationship between apo E genotypes and myasthenia gravis phenotypes. We tried to find any feature connected to the development of a different intensity of myasthenia gravis.
Marija Šoštarko +5 more
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Genotyping of Apolipoprotein E
2003Apolipoprotein E (apo E) is a 299-amino acid plasma protein involved in cholesterol transport and is found in chylomicrons, very low density lipopro-tein, intermediate-density lipoprotein, and high-density lipoprotein (1,1).
I. Cetin Ozturk +2 more
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Current Opinion in Neurology, 1996
Apolipoprotein E became relevant for neurologists in 1993 when the association of the apolipoprotein E-epsilon 4 allele with familial and sporadic late-onset Alzheimer disease was reported. Since that time, more than 100 confirmations and many research papers have appeared.
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Apolipoprotein E became relevant for neurologists in 1993 when the association of the apolipoprotein E-epsilon 4 allele with familial and sporadic late-onset Alzheimer disease was reported. Since that time, more than 100 confirmations and many research papers have appeared.
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Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1987We have previously demonstrated that astrocytes synthesize and secrete apolipoprotein E in situ. In the present work, primary cultures of rat brain astrocytes were used to study apolipoprotein E synthesis, secretion, and metabolism in vitro. The astrocytes in culture contained immunoreactive apolipoprotein E in the area of the Golgi apparatus ...
Susan H. Lee +4 more
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[10] Quantitation of apolipoprotein E
1996Quantitation of apoE has proved to be extremely useful in studies of the regulation of apoE synthesis and metabolism. Measurement of serum apoE and/or its distribution among the lipoprotein classes may have clinical utility, although this remains to be established.
Elaine S. Krul, Thomas G. Cole
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Apolipoprotein E phylogeny and evolution
Cell Biochemistry and Function, 2007AbstractAmong apolipoproteins, apolipoprotein E (Apo E) plays a pivotal role in lipid transport and is proposed to be involved in neural repair. Because of a long divergence history of apolipoproteins, it is unclear how Apo E evolved in time. To investigate relationships among Apo E proteins, we used the information from molecular data and analysed the
Ergül, Emel +3 more
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Arteriosclerosis and Thrombosis A Journal of Vascular Biology, 1994
We determined the common polymorphism of apolipoprotein E (E2, E3, and E4), apolipoprotein B Xba I polymorphism, and apolipoprotein C-III Sst I polymorphism in almost all Finnish centenarians alive in 1991 (n = 179/185).
J. Louhija +5 more
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We determined the common polymorphism of apolipoprotein E (E2, E3, and E4), apolipoprotein B Xba I polymorphism, and apolipoprotein C-III Sst I polymorphism in almost all Finnish centenarians alive in 1991 (n = 179/185).
J. Louhija +5 more
semanticscholar +1 more source
Non-apolipoprotein E and apolipoprotein E genetics of sporadic Alzheimer's disease
Ageing Research Reviews, 2009The genetic epidemiology of sporadic Alzheimer's disease (SAD) remains a very active area of research,making it one of the most prolifically published areas in medicine and biology. Numerous putative candidate genes have been proposed. However, with the exception of apolipoprotein E (APOE), the only confirmed genetic risk factor for SAD, all the other ...
Grazia D'Onofrio +7 more
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