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Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1987We have previously demonstrated that astrocytes synthesize and secrete apolipoprotein E in situ. In the present work, primary cultures of rat brain astrocytes were used to study apolipoprotein E synthesis, secretion, and metabolism in vitro. The astrocytes in culture contained immunoreactive apolipoprotein E in the area of the Golgi apparatus ...
R E, Pitas +4 more
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Non-apolipoprotein E and apolipoprotein E genetics of sporadic Alzheimer's disease
Ageing Research Reviews, 2009The genetic epidemiology of sporadic Alzheimer's disease (SAD) remains a very active area of research,making it one of the most prolifically published areas in medicine and biology. Numerous putative candidate genes have been proposed. However, with the exception of apolipoprotein E (APOE), the only confirmed genetic risk factor for SAD, all the other ...
SERIPA D +6 more
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Apolipoprotein in E in Myasthenia Gravis
Annals of the New York Academy of Sciences, 1998It is believed that apo E may moderate T lymphocytes by activation of mitogens or antigens. In that way, it has an influence on immune processes and it is reasonable to study the relationship between apo E genotypes and myasthenia gravis phenotypes. We tried to find any feature connected to the development of a different intensity of myasthenia gravis.
Šoštarko, Marija +5 more
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Genotyping of Apolipoprotein E
2003Apolipoprotein E (apo E) is a 299-amino acid plasma protein involved in cholesterol transport and is found in chylomicrons, very low density lipopro-tein, intermediate-density lipoprotein, and high-density lipoprotein (1,1).
I C, Ozturk, N, Akel, A A, Killeen
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Current Opinion in Neurology, 1996
Apolipoprotein E became relevant for neurologists in 1993 when the association of the apolipoprotein E-epsilon 4 allele with familial and sporadic late-onset Alzheimer disease was reported. Since that time, more than 100 confirmations and many research papers have appeared.
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Apolipoprotein E became relevant for neurologists in 1993 when the association of the apolipoprotein E-epsilon 4 allele with familial and sporadic late-onset Alzheimer disease was reported. Since that time, more than 100 confirmations and many research papers have appeared.
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Nihon rinsho. Japanese journal of clinical medicine, 1995
Apolipoprotein E (apo E) is one of the apolipoprotein components in very low density lipoproteins (VLDL) and high density lipoproteins (HDL). Apo E binds to low density lipoprotein (LDL) receptors and apo E-specific remnant receptors, and regulates remnant lipoprotein metabolism through these receptors in the liver.
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Apolipoprotein E (apo E) is one of the apolipoprotein components in very low density lipoproteins (VLDL) and high density lipoproteins (HDL). Apo E binds to low density lipoprotein (LDL) receptors and apo E-specific remnant receptors, and regulates remnant lipoprotein metabolism through these receptors in the liver.
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Arteriosclerosis, Thrombosis and Vascular Biology, 1995
V. Clavey +4 more
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V. Clavey +4 more
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