Results 41 to 50 of about 18,538,974 (359)

Apolipoprotein E and Atherosclerosis: From Lipoprotein Metabolism to MicroRNA Control of Inflammation. [PDF]

open access: yes, 2018
Apolipoprotein (apo) E stands out among plasma apolipoproteins through its unprecedented ability to protect against atherosclerosis. Although best recognized for its ability to mediate plasma lipoprotein clearance in the liver and protect against ...
Hasty   +6 more
core   +2 more sources

Interplay between RNA‐protein interactions and RNA structures in gene regulation

open access: yesFEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko   +2 more
wiley   +1 more source

Clinical study of APOE gene polymorphism combined with atorvastation in the treatment of chronic subdural hematoma

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery
Objective To explore the effect of APOE gene polymorphism on the clinical efficacy combined with oral atorvastatin in the treatment of chronic subdural hematoma (CSDH).
TAN Bao-dong   +5 more
doaj   +1 more source

Interaction of unilamellar liposomes with serum lipoproteins and apolipoproteins

open access: yesJournal of Lipid Research, 1980
The effect of rat whole blood plasma, serum, serum lipoproteins, and apolipoproteins on the stability of unilamellar liposomes prepared with French pressure cell was evaluated by measuring the release of entrapped carboxyfluorescein and by electron ...
L S Guo   +4 more
doaj   +1 more source

Characterisation of Antigen B Protein Species Present in the Hydatid Cyst Fluid of Echinococcus canadensis G7 Genotype. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2017
The larva of cestodes belonging to the Echinococcus granulosus sensu lato (s.l.) complex causes cystic echinococcosis (CE). It is a globally distributed zoonosis with significant economic and public health impact.
Ana Maite Folle   +9 more
doaj   +1 more source

Brain-targeted drug delivery by manipulating protein corona functions

open access: yesNature Communications, 2019
Protein corona presents a major obstacle to bench-to-bedside translation of targeted drug delivery systems, severely affecting targeting yields and directing unfavorable biodistribution.
Zui Zhang   +10 more
semanticscholar   +1 more source

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Electroimmunoassay of rat apolipoproteins A-I, A-IV, and E. A procedure for sample treatment to increase the sensitivity in diluted fractions.

open access: yesJournal of Lipid Research, 1985
Methods for the quantitative determination of rat apolipoproteins A-I, A-IV, and E by electroimmunoassay are described. Apolipoproteins present in diluted samples of biological fluids (approx.
G M Dallinga-Thie, P H Groot, A van Tol
doaj   +1 more source

Lipid and Protein Transfer between Nanolipoprotein Particles and Supported Lipid Bilayers. [PDF]

open access: yes, 2019
A nanolipoprotein particle (NLP) is a lipid bilayer disc stabilized by two amphipathic "scaffold" apolipoproteins. It has been most notably utilized as a tool for solubilizing a variety of membrane proteins while preserving structural and functional ...
Coleman, Matthew A   +4 more
core  

TREM2-dependent effects on microglia in Alzheimer\u27s Disease [PDF]

open access: yes, 2018
Alzheimer’s disease (AD) is a late-onset dementia characterized by the deposition of amyloid plaques and formation of neurofibrillary tangles (NFTs) which lead to neuronal loss and cognitive deficits.
Colonna, Marco   +2 more
core   +3 more sources

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