Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang +21 more
wiley +1 more source
Can Effective Apology Emerge Through Litigation? [PDF]
Gerhardstein provides a number of examples in which the factors identified by Roger Conner and Patricia Jordan--ripeness, a window of opportunity, and a symbolic act or gesture--came together to facilitate apology by a public leader.
Gerhardstein, Alphonse A.
core +1 more source
Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley +1 more source
On Gender and Apology: Case of Algerian Arabic
The present study explores the impact of gender on the use of apology strategies by Algerian speakers. Specifically, the research aims to identify the apology strategies utilized by male and female Algerian participants and to examine the potential ...
N. Derki
doaj +1 more source
Stolen Generations. After the Apology [PDF]
In Febraury 2008 the Prime Minister, Kevin Rudd delivered the National Apology to the Stolen Generations. Frontline asked NTEU Indigenous women to relate their feelings of the day,and how they feel the nation has progressed since.
Fredericks, Bronwyn L.
core +1 more source
The power of restorative apologies (real and imagined) for victims and offenders [PDF]
Shame can be felt after causing harm and after being harmed by wrongdoing. Failure to address shame can increase the possibility of the victim-offender overlap, making victims more likely to offend and offenders more likely to be victimized.
Walker Lorenn +2 more
doaj +1 more source
Living in to its Name and Living up to its Legacy: The public practical theology of KAIROS [PDF]
KAIROS Canada looks hopefully towards the emerging challenges of continuing public practical theology in a pluralistic, post-apology time and ...
Henry, Jennifer
core +1 more source
The Intentional Use of Service Recovery Strategies to Influence Consumer Emotion, Cognition and Behaviour [PDF]
Service recovery strategies have been identified as a critical factor in the success of. service organizations. This study develops a conceptual frame work to investigate how specific service recovery strategies influence the emotional, cognitive and ...
A. Palmer, R. Beggs, C. Keown-McMullan +61 more
core +2 more sources
Apology isn't good enough: an apology suppresses an approach motivation but not the physiological and psychological anger. [PDF]
Although studies have emphasized the multiple components of anger, little is known about the physiological and psychological mechanisms of the approach motivational component and the negative emotional component of anger.
Kenta Kubo +2 more
doaj +1 more source

