Results 121 to 130 of about 1,427,266 (249)

P402: MUTATIONS IN BONA FIDE ONCOGENES KRAS AND DNMT3A ARE NOT RELATED TO DEPENDENCY IN ESTABLISHED TUMORS, IN PDX MODELS OF ACUTE LEUKEMIA IN VIVO

HemaSphere, 2022
Y. Gao, M. Ghalandary, M. Becker, D. Amend, M. Rothenberg-Thurley, K. Metzeler, I. Jeremias   +6 more
doaj   +1 more source

Reduced apoptosis of CD8+ T-Lymphocytes in the airways of smokers with mild/moderate COPD

, 2011
Liboria Siena, Mark Gjomarkaj, John Elliot, Elisabetta Pace, Andreina Bruno, Simonetta Baraldo, Marina Saetta, Maria R. Bonsignore, Anthony James   +8 more
openalex   +2 more sources

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Piper betle stem extract induces apoptosis through mitochondria inactivation, p38MAPK activation and ErB2/ErbB3 suppression on oral squamous cell carcinoma cells

, 2022
M.-Y. Lee, Chi‐I Chang, Jen‐Jie Lin, Yu‐Jen Wu   +3 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

RSV temporally reprograms apoptosis and pyroptosis to balance immune evasion and replication. [PDF]

Sci Adv
Liu C, Zhou H, Li J, Meng Y, Wang J, He M, Wang W, Li Z, Qin Y, Chen M.   +9 more
europepmc   +1 more source

Short and Long Term Effects of Pomegranate (Punica Granatum) Extracts on Apoptosis in Rat Kidney Induced by Diethylnitrosamine and Phenobarbital [PDF]

, 2016
Asmaa Fathi Hamouda, Nadia Z. Shaban
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Can Environmental Enrichment Mitigate Cell Apoptosis in the Central Nervous System Under Adverse Health Conditions? A Systematic Review. [PDF]

Clin Transl Sci
de Sousa Fernandes MS, Ferreira DJS, Yagin FH, Badicu G, Santos GCJ, Guedes MCS, Souto FO, Ardigò LP.   +7 more
europepmc   +1 more source

Pterostilbene Induces Apoptosis from Endoplasmic Reticulum Stress Synergistically with Anticancer Drugs That Deposit Iron in Mitochondria [PDF]

Yukiko Nishiguch, Rina Fujiwara‐Tani, Shota Nukaga, Ryoichi Nishida, Ayaka Ikemoto, Rika Sasaki, Shiori Mori, Ruiko Ogata, Shingo Kishi, Yudai Hojo, Hisashi Shinohara, Masayuki Sho, Hiroki Kuniyasu   +12 more
openalex   +1 more source