Results 131 to 140 of about 1,019,500 (194)

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Quercetin Induces Apoptosis Through Downregulating P4HA2 and Inhibiting the PI3K/Akt/mTOR Axis in Hepatocellular Carcinoma Cells: An In Vitro Study. [PDF]

Cancer Rep (Hoboken)
Zhang J, Guo J, Qian Y, Yu L, Ma J, Gu B, Tang W, Li Y, Li H, Wu W.   +9 more
europepmc   +1 more source

Flow‐Induced Vascular Remodeling on‐Chip: Implications for Anti‐VEGF Therapy

Advanced Functional Materials, EarlyView.
Flow‐induced vascular remodeling plays a critical role in network stabilization and function. Using a vasculature‐on‐chip system, this study reveals how physiological VEGF levels and flow affect vascular remodeling and provides insights into tumor vessel normalization.
Fatemeh Mirzapour‐Shafiyi, Elias Huber, Leonie Karr, Johnny Tong, Andreas Richard Bausch, Friedrich Christian Simmel, Karen Alim   +6 more
wiley   +1 more source

A Visible Light‐Responsive Hydrogel to Study the Effect of Dynamic Tissue Stiffness on Cellular Mechanosensing

Advanced Functional Materials, EarlyView.
A visible light‐responsive polyacrylamide‐azobenzene hydrogel enables safe, reversible stiffness control for studying cell mechanobiology without harmful UV exposure. This approach reveals stem cells respond rapidly to mechanical changes, showing altered shape and protein distribution within one hour.
Aafreen Ansari, Sanchyan Bhowmik, Kaiwen Zhang, Chayla L. Reeves, Danielle Vahala, Yu Suk Choi, Amy Gelmi, Alexander N. Combes, Rocky S. Tuan, Vinh X. Truong, John S. Forsythe, Jessica E. Frith   +11 more
wiley   +1 more source

ABT-263, a BCL-2 inhibitor, selectively eliminates latently HIV-1-infected cells without viral reactivation. [PDF]

PLoS One
Kang JE, Seo HW, Kim DE, Shin YH, Bae S, Yoon CH.   +5 more
europepmc   +1 more source

Biomimetic Nanomedicines Deliver Naringin for Enhanced Acute Liver Failure Therapy via Balanced Regulation of Hepatocyte Oxidative Stress and Kupffer Cell Inflammation

Advanced Functional Materials, EarlyView.
A biomimetic nanomedicine (RBLN) constructed by loading natural antioxidants to clinically used layered double hydroxide nanoparticles is surface coated with fresh or senescent red blood cell membrane for balanced drug delivery to hepatocytes and KCs, thereby simultaneously alleviating liver oxidant stress and inflammation for effective drug‐induced ...
Jiahui Shao, Maoze Wang, Jinling Huang, Yu Wang, Jing Zhao, Ran Wang, Zhi Ping Xu, Jianping Jiang, Lingxiao Zhang   +8 more
wiley   +1 more source

Egg exosome miR-145-5p decreases mitochondrial ROS to protect chicken embryo hepatocytes against apoptosis through targeting MAPK10. [PDF]

J Anim Sci Biotechnol
Zhang F, Han Y, Li F, Guo B, Chen J, Zhou W, Xiao P, Ma H, Jin Y, Feng J, Min Y.   +10 more
europepmc   +1 more source

Magnetically Guided Mechanoactive Mineralization Scaffolds for Enhanced Bone Regeneration

Advanced Functional Materials, EarlyView.
A 3D‐printed ‘rebar‐concrete’ inspired scaffold (PGS‐P@MGel) synergizes spontaneous biomineralization with magneto‐mechanical stimulation through PDA@Fe3O4‐embedded hydrogel. This dual biointerface activates Piezo1/β‐catenin/YAP mechanotransduction axis, enhancing BMSCs osteogenesis and angiogenesis simultaneously.
Xuran Guo, Zaijin Tao, Zhenzhen Dai, Yinghua Gao, Chengzhen Chu, Cunyi Fan, Shen Liu, Xin Ma, Fangchun Jin, Zhengwei You, Jia Jiang   +10 more
wiley   +1 more source

Adverse Effect of Polystyrene Nanoplastics in Impairing Glucose Metabolism in Liver Injury. [PDF]

Int J Mol Sci
Susilo RJK, Pramudya M, Dewi FRP, Seftiarini W, Hidayati D, Aunurohim A, Lim V, Herdiansyah MA, Hayati A.   +8 more
europepmc   +1 more source