Results 151 to 160 of about 1,427,266 (249)

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Structural mechanism of VWF D’D3 dimer formation

Cell Discovery, 2022
Zimei Shu, Jianwei Zeng, Li Xia, Haiyan Cai, Aiwu Zhou   +4 more
doaj   +1 more source

Screening the Active Phytochemicals From <i>Eclipta prostrata</i> and Unraveling Their Molecular Insight Into Human Malignancies. [PDF]

Cancer Innov
Hossain MS, Khatun S, Mia MM, Zohora F, Sarker MR, Tanjida Islam KM, Sayeed MA, Mou MA, Hamidu S, Hamidu F, Wasaf Hasan AM, Mumtaj S, Hossain MK, Sohel M.   +13 more
europepmc   +1 more source

TLR4 regulates insulin-resistant proteins to increase apoptosis in the mouse retina

, 2017
Li Liu, Youde Jiang, Elizabeth Curtiss, Ken‐ichiro Fukuchi, Jena J. Steinle   +4 more
openalex   +2 more sources

Sodium benzylideneascorbate induces apoptosis in HIV‐replicating U1 cells [PDF]

, 1994
Kazumasa Aokia, Hideki Nakashima, Toshihiro Hattori, Daisuke Shiokawa, Ei-ichi Ni-imi, Yutaka Tanimoto, Hideharu Maruta, Fumiaki Uchiumi, M Kochi, Naoki Yamamoto, Sei-ichi Tanuma   +10 more
openalex   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Inhibition of GALNT7 suppresses cell proliferation and invasiveness while elevating cell apoptosis via the inactivation of the AKT pathway in non-small cell lung cancer. [PDF]

BMJ Open Respir Res
Zhou Y, Shi Y, Zhou J, Zhu X, Wei Z, Zhang Y.   +5 more
europepmc   +1 more source

Induction of apoptosis and differentiation by Na/H exchanger 1 modulation in acute myeloid leukemia cells

, 2019
Shin Young Hyun, Eun Jung Na, Ji Eun Jang, Haerim Chung, Soo‐Jeong Kim, Jin Seok Kim, Jee Hyun Kong, Kwang Yong Shim, Jong In Lee, Yoo Hong Min, June‐Won Cheong   +10 more
openalex   +2 more sources

Induction of Apoptosis by Rewiring the Signal Transduction of Epstein-Barr Virus Oncoprotein LMP1 toward Caspase Activation [PDF]

, 2005
Eudoxia Hatzivassiliou, Theodore Tsichritzis, George Mosialos   +2 more
openalex   +1 more source

Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa, Iago Pinal‐Fernandez, Pritikanta Paul, Michael P. Skolka, Margherita Milone, Min Shi, Mithun V. Shah, Maria Casal‐Dominguez, Katherine Pak, Andrew L. Mammen, Teerin Liewluck   +10 more
wiley   +1 more source