Results 181 to 190 of about 3,080,890 (389)

Cloning, expression, purification, and structural modeling of the Chandipura virus matrix protein

FEBS Open Bio, EarlyView.
This research protocol offers a guide for the cloning, expression, and purification of the Chandipura virus matrix protein using E. coli. It also includes a step‐by‐step procedure for cloning, expressing, and conducting fluorescence imaging of GFP‐fused Chandipura virus matrix protein in mammalian cell lines.
Mariana Grieben
wiley   +1 more source

Bimodal Fluorescence-Magnetic Resonance Contrast Agent for Apoptosis Imaging

, 2019
Hao Li, Giacomo Parigi, Claudio Luchinat, Thomas J. Meade   +3 more
openalex   +2 more sources

Mitochondrial complex I activity is impaired during HIV-1-induced T-cell apoptosis [PDF]

, 2005
Jayashree Ladha, Manoj Kumar Tripathy, Debashis Mitra   +2 more
openalex   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Inhibition of glucocorticoid-induced apoptosis by targeting splice variants of \u3ci\u3eBIM\u3c/i\u3e mRNA with small interfering RNA and short hairpin RNA. [PDF]

, 2004
Glucocorticoids (GCs) induce apoptosis in lymphocytes and are effective agents for the treatment of leukemia. The activated glucocorticoid receptor (GR) initiates a transcriptional program leading to caspase activation and cell death, but the critical ...
Abrams, Marc T., Robertson, Noreen M., Wickstrom, Eric, Yoon, Kyonggeun   +3 more
core   +1 more source

TP53-inducible Glycolysis and Apoptosis Regulator (TIGAR) Metabolically Reprograms Carcinoma and Stromal Cells in Breast Cancer [PDF]

, 2016
Ying‐Hui Ko, Marina Domingo‐Vidal, Megan Roche, Zhao Lin, Diana Whitaker‐Menezes, Erin L. Seifert, Claudia Capparelli, Madalina Tuluc, Ruth Birbe, Patrick Tassone, Joseph Curry, Àurea Navarro‐Sabaté, Ànna Manzano, Ramón Bartrons, J. Jaime, Ubaldo Martinez‐Outschoorn   +15 more
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Dexmedetomidine attenuates lipopolysaccharide-induced acute lung injury by inhibiting oxidative stress, mitochondrial dysfunction and apoptosis in rats

, 2016
Chunlai Fu, Xingui Dai, Yang You, Meng-xiang Lin, Yeping Cai, Shaoxi Cai   +5 more
openalex   +2 more sources

Heparin Reduces Neuroinflammation and Transsynaptic Neuronal Apoptosis in a Model of Subarachnoid Hemorrhage [PDF]

, 2012
J. Marc Simard, Çiğdem Tosun, Svetlana Ivanova, David B. Kurland, Caron M. Hong, Leanne Radecki, Carter Gisriel, Rupal I. Mehta, David L. Schreibman, Volodymyr Gerzanich   +9 more
openalex   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source