Results 1 to 10 of about 492 (130)

8-, 9-, and 11-Aryloxy Dimeric Aporphines and Their Pharmacological Activities [PDF]

Molecules, 2021
Aporphines, a major group of aporphinoid alkaloids, exhibit interesting and diverse pharmacological activities. A set of dimeric aporphines with an aryloxy group at C8, C9, and C11 have been isolated from six genera and shown to elicit various biological
Ghada Ali, Gregory D. Cuny
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The Non-Anhydrous, Minimally Basic Synthesis of the Dopamine D₂ Agonist [¹⁸F]MCL-524 [PDF]

Chemistry, 2021
The dopamine D2 agonist MCL-524 is selective for the D2 receptor in the high-affinity state (D2high), and, therefore, the PET analogue, [18F]MCL-524, may facilitate the elucidation of the role of D2high in disorders such as schizophrenia.
James A. H. Inkster, Anna W. Sromek, Vamsidhar Akurathi, John L. Neumeyer, Alan B. Packard   +4 more
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Bioactive aporphines and flavonoids from a fermented beverage target metabolic inflammatory pathways in obesity and type 2 diabetes [PDF]

Scientific Reports
The global syndemic of obesity and type 2 diabetes (T2D) demands safe, multi-targeted dietary interventions. FH03FS, a sterilized fermented beverage blended from five medicinal food homologous (MFH) plants, represents a promising candidate.
Xiurong Wu, Yang Qiu, Rui Dai, Zixu Huang, Jinghan Wang, Xiantao Yan, Xiangzhen Nie, Ronghan Liu   +7 more
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Comparative metabolite analysis of Piper sarmentosum organs approached by LC–MS-based metabolic profiling [PDF]

Natural Products and Bioprospecting
Piper sarmentosum Roxb. (Piperaceae) is a traditional medicinal and food plant widely distributed in the tropical and subtropical regions of Asia, offering both health and culinary benefits.
Ismail Ware, Katrin Franke, Andrej Frolov, Kseniia Bureiko, Elana Kysil, Maizatulakmal Yahayu, Hesham Ali El Enshasy, Ludger A. Wessjohann   +7 more
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Hypecoum spp.—Chemistry and Biological Activity of Alkaloids

Diversity, 2023
Genus Hypecoum Tourn. ex L. belongs to the poppy family Papaveraceae and comprises about 19 species occurring in Europe, Northern Africa and Asia.
Nadezhda Kostova, Tsvetelina Doncheva
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Assessment of Insecticidal Activity of Benzylisoquinoline Alkaloids from Chilean Rhamnaceae Plants against Fruit-Fly Drosophila melanogaster and the Lepidopteran Crop Pest Cydia pomonella

Molecules, 2020
The Chilean plants Discaria chacaye, Talguenea quinquenervia (Rhamnaceae), Peumus boldus (Monimiaceae), and Cryptocarya alba (Lauraceae) were evaluated against Codling moth: Cydia pomonella L.
Soledad Quiroz-Carreño, Edgar Pastene-Navarrete, Cesar Espinoza-Pinochet, Evelyn Muñoz-Núñez, Luis Devotto-Moreno, Carlos L. Céspedes-Acuña, Julio Alarcón-Enos   +6 more
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Isolation and identification of the alkaloids from rhizomes of Stephania macrantha

Guangxi Zhiwu, 2023
To study the alkaloids in the rhizomes of Stephania macrantha. The total alkaloids of S. macrantha were extracted by acid extraction and alkali precipitation method. Eleven alkaloids have been isolated and purified by silica gel column chromatography and
Guofeng SUN, Fengzheng CHEN, Chong TIAN, Ying CHENG, Shuhua LI   +4 more
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Total Synthesis and Antimicrobial Activity of (±)-Laurelliptinhexadecan-1-one and (±)-Laurelliptinoctadecan-1-one

Molecules, 2008
The structures previously assigned to (+)-laurelliptinhexadecan-1-one (1a) and (+)-laurelliptinoctadecan-1-one (1b) from Cocculus orbiculatus (L.) DC. (Menispermaceae) have been confirmed by total synthesis of the racemic alkaloids.
Surachai Nimgirawath, Phansuang Udomputtimekakul, Samathi Pongphuttichai, Thongchai Taechowisan, Asawin Wanbanjob   +4 more
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Oxoisoaporphines and Aporphines: Versatile Molecules with Anticancer Effects

Molecules, 2019
Cancer is a disease that involves impaired genome stability with a high mortality index globally. Since its discovery, many have searched for effective treatment, assessing different molecules for their anticancer activity.
Esteban Rodríguez-Arce, Patricio Cancino, Manuel Arias-Calderón, Paul Silva-Matus, Marianela Saldías   +4 more
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Antioxidant and Anticancer Constituents from the Leaves of Liriodendron tulipifera

Molecules, 2014
Sixteen compounds were extracted and purified from the leaves of Liriodendron tulipifera. These compounds include aporphines, oxoaporphine, coumarin, sesquiterpene lactone, benzenoids, cyclitol and steroids.
Ya-Fei Kang, Chi-Ming Liu, Chiu-Li Kao, Chung-Yi Chen   +3 more
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