Results 21 to 30 of about 492 (130)

The Elevation of LC-ESI-Q-TOF-MS Response in the Analysis of Isoquinoline Alkaloids from Some Papaveraceae and Berberidaceae Representatives

Journal of Analytical Methods in Chemistry, 2017
Twenty-five methanol extracts obtained from various representatives of Papaveraceae and Berberidaceae botanical families (genera: Papaver, Argemone, Eschscholzia, Chelidonium, Glaucium, and Berberis) were screened for their alkaloid content in an ...
Wirginia Kukula-Koch
doaj   +1 more source

Liquid Chromatography Coupled with Linear Ion Trap Hybrid OrbitrapMass Spectrometry for Determination of Alkaloids in Sinomeniumacutum

Molecules, 2018
The characterization of alkaloids is challenging because of the diversity of structures and the complicated fragmentation of collision induced structural dissociation in mass spectrometry.
Jinjun Shan, Xia Zhao, Cunsi Shen, Jianjian Ji, Jianya Xu, Shouchuan Wang, Tong Xie, Wenjun Tong   +7 more
doaj   +1 more source

Synthesis and Structure-Activity Relationships of a Series of Aporphine Derivatives with Antiarrhythmic Activities and Acute Toxicity

Molecules, 2016
Some aporphine alkaloids, such as crebanine, were found to present arrhythmic activity and also higher toxicity. A series of derivatives were synthesized by using three kinds of aporphine alkaloids (crebanine, isocorydine, and stephanine) as lead ...
Hui Wang, Xin Cheng, Shujun Kong, Zixian Yang, Hongmei Wang, Qiuyan Huang, Jingyu Li, Cheng Chen, Yunshu Ma   +8 more
doaj   +1 more source

New Aporphine Alkaloids from Guatteria foliosa

Journal of Natural Products, 1994
Four new alkaloids were obtained from Guatteria foliosa, namely, the noraporphines (-)-3-methoxyputerine [1] and (+)-norguattevaline [2], the more highly oxidized (+)-3-methoxyguattescidine [3], and the oxoaporphine 3-methoxyoxoputerine [4].
Mahiou, V., Roblot, F., Hocquemiller, R., Cavé, A., Rojas de Arias, A., Inchausti, A., Yaluff, G., /Fournet, Alain, Angelo, A.   +8 more
openaire   +3 more sources

Chemical Constituents and Biological Activities of Oxandra (Annonaceae): A Review

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT Oxandra (Annonaceae) comprises 29 species distributed across South and Central America. Despite this diversity, the genus remains under‐investigated. This study presents the first comprehensive review of the chemical composition and biological activities of Oxandra species, utilizing databases such as SciFinder, ScienceDirect, PubMed, and ...
Rayssa Cota Lopes, Francisco Paiva Machado, Mateus de Freitas Brito, Thalisson Amorim de Souza, Lucas Silva Abreu   +4 more
wiley   +1 more source

Phenanthrene Alkaloids From Guatteria Olivacea as Topoisomerase II Inhibitors: Theoretical Insights and Cytotoxic Evaluation

ChemistrySelect, Volume 11, Issue 2, 15 January 2026.
Three phenanthrene alkaloids from Guatteria olivacea were studied by DFT, docking, MD, and cytotoxicity assays. All compounds showed stable binding to DNA–topoisomerase II and human serum albumin. Atherosperminine exhibited cytotoxic activity against four cancer cell lines, supporting its potential as a topoisomerase II inhibitor and anticancer ...
Renyer A. Costa, Victor L. Tananta, Ianni de O. Corrêa, Jamelah S. Al‐Otaibi, Y. Sheena Mary, Milena Botelho P. Soares, Daniel P. Bezzera, Morgana de S. Araújo, Emmanoel V. Costa   +8 more
wiley   +1 more source

Expanding the Reach of Membrane Protein–Ligand Interaction Studies Through the Integration of Mass Spectrometry and Membrane Mimetics

PROTEOMICS, Volume 25, Issue 21-22, Page 25-40, November 2025.
ABSTRACT Mass spectrometry (MS) offers robust, label‐free approaches for characterizing ligand–protein interactions through two main strategies: affinity‐based and stability‐based assays. However, their application to membrane proteins (MPs)—a major class of drug targets—has been limited by challenges such as structural complexity, low native ...
Jonathon C. Lambos, Ashim Bhattacharya, Mohammed Al‐Seragi, Franck Duong van Hoa   +3 more
wiley   +1 more source

White Light‐Induced Slow Kinetics Generation of Arynes

European Journal of Organic Chemistry, Volume 28, Issue 36, September 29, 2025.
2‐(3‐Acetyl‐3‐methyl‐1‐triazen‐1‐yl)benzoic acids are synthesized from anthranilic acids, enabling the generation of arynes under white light irradiation. These aryne photoprecursors participate in [3 + 2] and [4 + 2] cycloadditions, as well as in metal‐free CN couplings, with good functional group tolerance.
Vinícius V. Souza, Marcos Accioly Jr, Cristiano Raminelli   +2 more
wiley   +1 more source

Comprehensive Metabolomic Profiling and Biological Activity Analysis of Eschscholzia californica Extracts Using LC‐ESI‐QTOF‐MS

Food Science &Nutrition, Volume 13, Issue 9, September 2025.
The results indicate the potential pharmacological applications of Eschscholzia californica's aerial parts as a source for the development of novel phytopharmaceuticals targeting conditions such as insomnia, schizophrenia, and depression. ABSTRACT The current investigation was designed to explore the chemical composition, antioxidant capacity, enzyme ...
Alina Kalyniukova, Shakeel Ahmed, Gunes Ak, Enver Saka, Tugce Duran, Nurgul Abul, Ilhami Gulcin, Ismail Senkardes, Mehmet Veysi Cetiz, Gokhan Zengin   +9 more
wiley   +1 more source

LC‐DAD‐MSn and HR‐LC‐QTOF Analysis of Ziziphus budhensis Leaves and Evaluation of Their In Vitro and In Vivo Biological Activities

Chemistry &Biodiversity, Volume 22, Issue 8, August 2025.
ABSTRACT Ziziphus budhensis Bhattarai & M.L. Pathak is a specie described in 2015 in Nepal poorly studied for its phytochemical composition and possible bioactivities. In this study, six extracts were obtained from Z. budhensis leaves using ultrasound assisted extraction with solvents in increasing polarity namely hexane, dichloromethane, chloroform ...
Samjhana Bharati, Binita Maharjan, Timila Shrestha, Shyam Sharan Shrestha, Stefania Sut, Hari Prasad Devkota, Ram Lal Swagat Shrestha, Stefano Dall'Acqua   +7 more
wiley   +1 more source