Results 31 to 40 of about 492 (130)
Nonconventional Techniques in Plant Alkaloid Extraction: A Decade of Progress (2014–2023)
Chemistry &Biodiversity, Volume 22, Issue 8, August 2025.This figure seeks to represent the evolution of the different unconventional approaches that were adopted for the extraction of plant‐derived alkaloids during the decade from 2014 to 2023. ABSTRACT Plant metabolism encompasses primary and secondary pathways, with secondary metabolism yielding diverse natural products crucial for plant adaptation and ...
Victor Menezes Sipoloni +5 more
wiley +1 more source
Progress on the development of Class A GPCR‐biased ligands
British Journal of Pharmacology, Volume 182, Issue 14, Page 3249-3300, July 2025.Class A G protein‐coupled receptors (GPCRs) continue to garner interest for their essential roles in cell signalling and their importance as drug targets. Although numerous drugs in the clinic target these receptors, over 60% GPCRs remain unexploited. Moreover, the adverse effects triggered by the available unbiased GPCR modulators, limit their use and
Paula Morales +20 more
wiley +1 more source
Entomologia Experimentalis et Applicata, Volume 173, Issue 7, Page 696-707, July 2025.We studied the response of Battus polydamas (Papilionidae) larvae fed on Aristolochia ringens (containing several diterpenes) and Aristolochia gigantea (containing sesquiterpenes and acyclic monoterpenoids but no diterpenoids or aristolochic acids). We assessed larval performance on fitness components such as survival and differential gene expression ...
Karina L. Silva‐Brandão +3 more
wiley +1 more source
Mechanisms and Therapeutic Strategies of Macrophage Polarization in Intervertebral Disc Degeneration
JOR SPINE, Volume 8, Issue 2, June 2025.This article reviews the role of macrophage polarization in IVDD. It details how macrophage polarization influences various pathomechanisms of disc degeneration, including the inflammatory microenvironment, NPCs senescence, angiogenesis, fibrosis, and neural ingrowth and sensitization.
Kaiyuan Zheng +6 more
wiley +1 more source
Review of larval food plant associations of the Agaristinae (Lepidoptera: Noctuidae) in Australia
Austral Entomology, Volume 64, Issue 2, May 2025.Abstract The Australian Agaristinae comprises a small group of predominantly diurnal moths with aposematic larvae and adults that are assumed to be unpalatable to most predators. A critical review of the larval food plants of this subfamily based on published records in the literature, together with unpublished records, is presented.
Michael F. Braby
wiley +1 more source
The Plant Journal, Volume 121, Issue 5, March 2025.SUMMARY Plant specialized metabolites play key roles in diverse physiological processes and ecological interactions. Identifying structurally novel metabolites, as well as discovering known compounds in new species, is often crucial for answering broader biological questions.
Tito Damiani +8 more
wiley +1 more source
The Effect of a Novel Functional Solid Drink on Obesity Management and Its Underlying Mechanisms
eFood, Volume 6, Issue 1, February 2025.We have successfully developed a novel functional solid beverage for obesity management, named RLMCR, composed of lotus leaf, mulberry leaf, sweet tea, Cassia seed, and rose. The liquid chromatography‐tandem mass spectrometry (LC‐MS/MS) analysis revealed that RLMCR contains numerous active components, including flavonoids, polyphenols, and terpenoids ...
Ying Wen +13 more
wiley +1 more source
Food Frontiers, Volume 6, Issue 1, Page 65-85, January 2025.• Overviewed edible TCMs for their hypoglycemic and hypolipidemic potentials • Reviewed screening strategies for bioactive compounds in edible TCMs by UF/LC‐MS • Updated molecular mechanisms of hypoglycemic and hypolipidemic compounds in edible TCMs • Prospected future trends and challenges in more efficient multi‐target based UF/LC‐MS Abstract Edible ...
Xiaowen Hua +8 more
wiley +1 more source
Clastogenicity of Aporphine Alkaloids in Vitro.
Journal of Pharmacobio-Dynamics, 1992 The chromosomal aberration test using a Chinese hamster lung cell line (CHL) was carried out on 19 aporphine alkaloids including apomorphine with and without rat liver homogenates (S9) mix. Eighteen of 19 alkaloids tested induced chromosomal aberration in the presence or absence of S9 mix.
S, Tadaki +6 more
openaire +3 more sources
Traditional &Kampo Medicine, Volume 11, Issue 1, Page 83-85, April 2024.Abstract Four young researchers presented their studies in the field of traditional Japanese herbal medicine (Wakan‐yaku) at the Fourth Annual Young Researcher Forum held the day before the 2023 annual meeting of the Japan Society of Medical and Pharmaceutical Sciences for Traditional Medicine.
Tetsuhiro Yoshino +7 more
wiley +1 more source