Results 81 to 90 of about 492 (130)

Nuciferine reduces vascular leakage and improves cardiac function in acute myocardial infarction by regulating the PI3K/AKT pathway. [PDF]

Sci Rep
Xie W, Chen S, Wang W, Qin X, Kong C, Wang D.   +5 more
europepmc   +1 more source

Review: Dicranostigma leptopodum: A peculiar plant of Papaveraceae. [PDF]

Open Life Sci
Tian Y, Geng Y, Zhang Y, Zhao Z, Ruan L, Zhang C.   +5 more
europepmc   +1 more source

N-Arylsulfonylated C-Homoaporphines as a New Class of Antiplatelet and Antimicrobial Agents. [PDF]

ACS Med Chem Lett
Shyamlal BRK, Mahajan AT, Kumar V, Gupta A, Shrivastava Ronin R, Mathur M, Sen J, Chaudhary S.   +7 more
europepmc   +1 more source

Effects of organic salts of virucidal and antiviral compounds from Nelumbo nucifera and Kaempferia parviflora against SARS-CoV-2. [PDF]

Sci Rep
Yang DD, Chutiwitoonchai N, Wang F, Tian P, Sureram S, Lei X, Mahidol C, Ruchirawat S, Kittakoop P.   +8 more
europepmc   +1 more source

Synthetic aporphine alkaloids are potential therapeutics for Leigh syndrome. [PDF]

Sci Rep
Kobayashi M, Miyauchi A, Jimbo EF, Oishi N, Aoki S, Watanabe M, Yoshikawa Y, Akiyama Y, Yamagata T, Osaka H.   +9 more
europepmc   +1 more source

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Aporphines. 31. Synthesis and antitumor activity of aporphine nitrogen mustards

Journal of Medicinal Chemistry, 1980
A series of aporphine nitrogen mustards and their congeners (1b-g) has been prepared. N-[[Bis(2-chloroethyl)-amino]-2,11-dihyroxy-10-methoxynoraporphine (1b) and its mono- and diacetyl ester derivatives (1c-d) were prepared from N-(chloroacetyl)-2,11-diacetoxy-10-methoxynoraporphine (2).
J L, Neumeyer, F E, Granchelli, C N, Filer, A H, Soloway, S J, Law   +4 more
openaire   +2 more sources

New Analogues of Aporphine Alkaloids

Mini-Reviews in Medicinal Chemistry, 2018
Aporphine alkaloids, characterized by a heterocyclic aromatic basic skeleton, are known from different organisms and exhibit various biological activities: anti-tumor, anti-viral, anti-microbial, anti-inflammatory etc. The review gives information which provides an overview of the latest progress in the structural diversity and the biological activity ...
Yi-Chao, Ge, Kui-Wu, Wang
openaire   +2 more sources

New Cytotoxic Tetrahydroprotoberberine-Aporphine Dimeric and Aporphine Alkaloids fromCorydalis turtschaninovii

Planta Medica, 2010
Two new tetrahydroprotoberberine-aporphine dimeric alkaloids, corydaturtschines A (1) and B (2), and a new aporphine derivative, ethyl glausuccinate (3), together with 13 known protoberberine (4-16) and nine known aporphine alkaloids (17-25), were isolated from the tubers of Corydalis turtschaninovii.
Ki Hyun, Kim, Cheng Jie, Piao, Sang Un, Choi, Mi Won, Son, Kang Ro, Lee   +4 more
openaire   +2 more sources

Aporphines. 22. Electrochemical synthesis of aporphines via cathodic cyclization of iodobenzylisoquinolinium salts

Journal of the American Chemical Society, 1976
Elektrolyse der Isochino1inium- Salze (I) liefert die Cyclisierungsprodukte (II), aus denen durch katalytische Hydrierung die Aporphine (III) gewonnen werden [keine Isolierung von (IIb); keine Ausbeuteangabe fur (IIIb)].
R, Gottlieb, J L, Neumeyer
openaire   +2 more sources

Aporphines 15 action of aporphine alkaloids on dopaminergic mechanisms in rat brain

European Journal of Pharmacology, 1976
Of eleven aporphine analogues tested on striatal adenylate cyclase only (-)-apomorphine and (+/-)-N-n-propyl-norapomorphine (+/-(NPA)) were effective in stimulating the cyclase from rat brain. Inactive compounds included (+/-)-isoapomorphine, (-)-1,2-dihydroxyaporphine and (+/-)-10-hydroxy-N-n-propylnoraporphine.
R J, Miller, P H, Kelly, J L, Neumeyer
openaire   +2 more sources