Results 121 to 130 of about 532 (257)

Tackling toxicity in Arabic social media through advanced detection techniques. [PDF]

Sci Rep
Hatem L, Omar A, Ali AA, Farghaly HM.
europepmc   +1 more source

Structure-based rational design of an enhanced fluorogen-activating protein for fluorogens based on GFP chromophore. [PDF]

Commun Biol, 2022
Goncharuk MV, Baleeva NS, Nolde DE, Gavrikov AS, Mishin AV, Mishin AS, Sosorev AY, Arseniev AS, Goncharuk SA, Borshchevskiy VI, Efremov RG, Mineev KS, Baranov MS.   +12 more
europepmc   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

People do change their beliefs about conspiracy theories-but not often. [PDF]

Sci Rep
Williams MN, Ling M, Kerr JR, Hill SR, Marques MD, Mawson H, Clarke EJR.   +6 more
europepmc   +1 more source

The CRISPR-associated Cas4 protein from Leptospira interrogans demonstrate versatile nuclease activity. [PDF]

Curr Res Microb Sci, 2021
Dixit B, Anand V, Hussain MS, Kumar M.
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

The structure-function analysis of Obg-like GTPase proteins along the evolutionary tree from bacteria to humans. [PDF]

Genes Cells, 2022
Chakraborty A, Halder S, Kishore P, Saha D, Saha S, Sikder K, Basu A.   +6 more
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Investigating the causal effects of religiosity on childbearing among U.S. adolescents using a three-wave longitudinal design. [PDF]

Sci Rep
Chvaja R, Shaver JH, Bulbulia JA.
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source