Results 71 to 80 of about 1,807 (209)
Immunoglobulin binding protein (BiP) forms two types of dimers
Abstract Immunoglobulin binding protein (BiP) is a chaperone protein that plays crucial roles in protein folding and transport by binding unfolded proteins in the substrate binding domain (SBD), an interaction allosterically linked to the nucleotide occupancy of the nucleotide binding domain (NBD).
Karina New +6 more
wiley +1 more source
Notas sobre la autonomía de la voluntad de las personas vulnerable en el ámbito socio-sanitario
El presente artículo repasa las distintas herramientas que nuestro ordenamiento jurídico pone a disposición de las personas vulnerables con la finalidad de hacer valer la autonomía de la voluntad y su dignidad como sujetos de ...
Leticia Hernández Martínez
doaj
Cementum attachment protein‐derived peptides adsorb to specific crystallographic faces of brushite and calcium oxalate, blocking calcium deposition. This phosphorylation‐enhanced modulation alters crystal growth under conditions in vitro, leading to the formation of irregular brushite crystals and rosette‐like calcium oxalate morphologies.
Alberto Mimila‐Cortes +9 more
wiley +1 more source
ABSTRACT Titanium dioxide (TiO2), used as a food additive (labeled E171 in Europe), was withdrawn from the European market in 2022. The E171 toxicity mechanism involves its uptake, oxidative stress, DNA damage, and inflammation. It has been hypothesized that the TiO2 accumulation nanoparticles (NPs) or E171 triggers tissue damage, and some studies have
Carmen Ximena Martínez‐Escutia +3 more
wiley +1 more source
El siguiente trabajo tiene como objetivo presentar algunos de los resultados durante el desarrollo del proyecto titulado “Centro Cultural y Artístico Itinerante de Divulgación Científica, Tecnológica y Humanística con Poblaciones en Condiciones de ...
Ana Laura Castillo Hernández +1 more
doaj +1 more source
Descripción: Como beneficiario del programa de Incorporación de Investigadores al Sistema Nacional de Salud (FIS) que desarrolla su actividad profesional en un hospital universitario, y conocedor (y “sufridor”) de los problemas de la investigación biomédica en nuestro ámbito, veo con agrado la iniciativa aquí recogida de apoyo a la investigación en el ...
openaire +1 more source
Dendrimeric Antigens for Passive Mast Cell Activation in the Evaluation of Amoxicillin Allergy
DeAns with defined nanoscale structure reveal that conjugate size and determinant density govern IgE‐mediated effector‐cell activation in AX allergy. All DeAn generations bind to sIgE in inhibition immunoassay, but only larger DeAns trigger FcεRI‐dependent responses in mouse MC, huRBL‐2H3, and LUVA cells.
Amene Tesfaye Ayane +12 more
wiley +1 more source
Successful Application of the Mast Cell Activation Test in Immediate Hypersensitivity to Amoxicillin
This study included 28 amoxicillin‐allergic patients and 11 healthy exposed controls. Mast cells were differentiated from CD34+ progenitors over 8 weeks using cytokine cocktails. The mast cell activation test involved sensitization with patient or control sera and stimulation with free amoxicillin or G4/G5‐AXO dendrimers with successfully activated ...
Jose A. Céspedes +11 more
wiley +1 more source
[Attitudes of neighbors about the treatment and community life of people with severe mental health disorders in Argentina]. [PDF]
García E +5 more
europepmc +1 more source
Background and Purpose α‐Synucleinopathies are neurodegenerative disorders characterized by the aggregation and propagation of misfolded α‐synuclein. In Parkinson's disease (PD), the most common α‐synucleinopathy, the progression of motor and nonmotor deficits, and dopaminergic neuron loss, are closely linked to the spreading of misfolded α‐synuclein ...
Alberto Santiago‐Balmaseda +5 more
wiley +1 more source

