Results 81 to 90 of about 2,845,265 (325)

The Value of Diffusion-Weighted Magnetic Resonance Imaging in Predicting the Efficacy of Radiation and Chemotherapy in Cervical Cancer

Open Life Sciences, 2018
To analyze the application value of apparent diffusion coefficient (ADC) and exponent apparent diffusion coefficient (EADC) in evaluating the efficacy of radiation and chemotherapy in cervical cancer using pre- and posttreatment diffusion-weighted ...
Chen Jingjing, Hua Hui, Pang Jing, Shi Xianglong, Bi Weiqun, Li Yingduan, Xu Wenjian   +6 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Viscosity and mass diffusion coefficient of ammonia/ethylammonium nitrate mixtures

, 2021
Ethylammonium nitrate shows an enhanced ammonia solubility due to the formation of strong hydrogen bonds. This protic ionic liquid also shows negligible vapour pressure and shares many properties with water.
Salavera, Daniel, Coronas Salcedo, Alberto, Rives Sanz, Ronny   +2 more
core   +1 more source

Wet and dry cup test with hygroscopic materials: what do we really measure?

InterPore Journal
Wet and dry cup tests are widely used to characterize the vapor permeability (or the apparent vapor diffusion coefficient) of construction materials. From a theoretical approach, we examined the transport characteristics of such tests in detail.
Yuliang Zou, Elea Moss, Laurent Brochard, Philippe Coussot   +3 more
doaj   +1 more source

Diffusion weighted imaging in high-grade gliomas: A histogram-based analysis of apparent diffusion coefficient profile.

PLoS ONE, 2021
PurposeGlioblastoma and anaplastic astrocytoma represent the most commonly encountered high-grade-glioma (HGG) in adults. Although both neoplasms are very distinct entities in context of epidemiology, clinical course and prognosis, their appearance in ...
Georg Gihr, Diana Horvath-Rizea, Elena Hekeler, Oliver Ganslandt, Hans Henkes, Karl-Titus Hoffmann, Cordula Scherlach, Stefan Schob   +7 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Detection and modeling of non-Gaussian apparent diffusion coefficient profiles in human brain data [PDF]

, 2002
This work details the observation of non-Gaussian apparent diffusion coefficient (ADC) profiles in multi-direction, diffusion-weighted MR data acquired with easily achievable imaging parameters (b 1000 s/mm2).
BARKER, G. J.; id_orcid, Arridge, S.R., ALEXANDER, D. C., Alexander, D.C., ARRIDGE, S. R., Barker , G.J.   +5 more
core   +1 more source

Apparent diffusion coefficients in oligodendroglial tumors characterized by genotype [PDF]

Journal of Magnetic Resonance Imaging, 2007
AbstractPurposeTo investigate whether oligodendroglial tumors with or without 1p/19q loss differ in their diffusion‐weighted imaging characteristics. Oligodendroglial tumors with or without 1p/19q loss differ in their therapeutic responsiveness and prognosis, and recent reports also suggest that these tumors may differ in their magnetic resonance ...
Michael D, Jenkinson, Trevor S, Smith, Andrew R, Brodbelt, Kathy A, Joyce, Peter C, Warnke, Carol, Walker   +5 more
openaire   +2 more sources

Relationship between apparent diffusion coefficient and tumour cellularity in lung cancer. [PDF]

PLoS ONE, 2014
BACKGROUND AND OBJECTIVE: To prospectively investigate the relationship between the apparent diffusion coefficient (ADC) and cellularity in lung cancer.
Lihua Chen, Jiuquan Zhang, Yongfeng Chen, Wenwei Wang, Xiangdong Zhou, Xiaochu Yan, Jian Wang   +6 more
doaj   +1 more source